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Spectrofluorimetric determination of clioquinol in pharmaceutical preparations

  • Pharmaceutical And Clinical Samples
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Summary

The fluorescence of metal complexes of clioquinol (5-chloro-7-iodo-8-hydroxyquinoline) in micellar media is described. The relationship between fluorescence intensity and experimental variables was studied in order to develop a procedure for the fluorimetric determination of clioquinol with In(III) in CTAB medium. Linear calibrations were obtained in the ranges 5×10−5–2.5×10−6 mol/l and 2.5×10−6–5×10−8 mol/l. The method was successfully applied to the determination of clioquinol in pharmaceutical preparations.

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References

  1. U. S. Pharmacopoeia (1985) pp 227–229

  2. British Pharmacopoeia (1988) vol I, pp 144–145

  3. Bosch E, Guiteras J, Izquierdo A (1988) J Pharm Bio Anal 6:983–986

    Google Scholar 

  4. Fernández Gutierrez A, Muñoz de la Peña A (1985) In: Schulman SG (ed) Molecular luminescence spectroscopy: methods and applications, Part I. Wiley, New York, p 430

    Google Scholar 

  5. Kina K, Tamura K, Ishibashi N (1974) Bunseki Kagaku 23:1404–1406 (Chem Abs 82:164470)

    Google Scholar 

  6. Phillips DA, Soroka A, Vithanage RS, Dasgupta PK (1986) Mikrochim Acta 207–220

  7. Sanz Medel A, Fernández de la Campa R, García JI (1987) Analyst 112:493–497

    Google Scholar 

  8. Salinas F, Muñoz de la Peña A, Duran MS (1988) Anal Lett 21:1457–1468

    Google Scholar 

  9. Compañó R, Grima A, Izquierdo A, Prat MD (1989) Anal Chim Acta 227:219–226

    Google Scholar 

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Authors and Affiliations

  1. Department of Analytical Chemistry, University of Barcelona, Diagonal 647, E-08028, Barcelona, Spain

    J. Giménez-Izquierdo, J. Guiteras, A. Izquierdo & M. D. Prat

Authors
  1. J. Giménez-Izquierdo
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  2. J. Guiteras
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  3. A. Izquierdo
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  4. M. D. Prat
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Giménez-Izquierdo, J., Guiteras, J., Izquierdo, A. et al. Spectrofluorimetric determination of clioquinol in pharmaceutical preparations. Fresenius J Anal Chem 341, 638–640 (1991). https://doi.org/10.1007/BF00322278

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  • DOI: https://doi.org/10.1007/BF00322278

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