Summary
The oxidation of formaldehyde to carbon dioxide in cell-free extracts of methanol-grown Candida boidinii has been investigated. A specific NAD-dependent formaldehyde dehydrogenase requiring reduced glutathione has been partially purified. Furthermore, a NAD-linked formate dehydrogenase was found in cell-free extracts. The synthesis of these two enzymes is induced by methanol and repressed by glucose. The possible significance of these enzymes in the energy-generating system is discussed.
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Sahm, H., Wagner, F. Mikrobielle Verwertung von Methanol. Archiv. Mikrobiol. 90, 263–268 (1973). https://doi.org/10.1007/BF00424978
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DOI: https://doi.org/10.1007/BF00424978