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Microbiological oxidation of the branched C5-dicarboxylic acids

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Summary

The oxidation of branched C5-dicarboxylates has been studied with microorganisms obtained from enrichement cultures with each of these acids. Bacteria grown on itaconate, mesaconate or methylsuccinate oxidize most of these compounds rapidly; (+) citramalate is oxidized 2–4 times as rapidly as (-) citramalate; and citraconate only feebly. Citraconate-grown cells do not oxidize itaconate and oxidize feebly mesaconate and methylsuccinate; they oxidize (-) citramalate 3–4 times faster than (+) citramalate. Cell-free extracts of various strains grown on different C5-dicarboxylates contain pronounced mesaconase activity, varying amounts of citraconase and hardly any itaconase activity.

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Authors and Affiliations

  1. Division of Biochemistry, National Chemical Laboratory, Poona-8, India

    V. S. Krishnamachar, S. S. Subramanian & M. R. Raghavendra Rao

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  1. V. S. Krishnamachar
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  2. S. S. Subramanian
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  3. M. R. Raghavendra Rao
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Communication number 633 from National Chemical Laboratory.

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Krishnamachar, V.S., Subramanian, S.S. & Raghavendra Rao, M.R. Microbiological oxidation of the branched C5-dicarboxylic acids. Archiv. Mikrobiol. 47, 338–343 (1964). https://doi.org/10.1007/BF00406358

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  • DOI: https://doi.org/10.1007/BF00406358

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