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Guanylcobamide and hypoxanthylcobamide-Corrinoids formed by Desulfovibrio vulgaris

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Abstract

The corrinoids synthesized by the sulfate-reducing bacterium Desulfovibrio vulgaris were analyzed. The compounds found were guanylcobamide and hypoxanthylcobamide; structures were determined by mass spectrometry, 1H-NMR, and ultraviolet/visible spectroscopy. D. vulgaris used externally added guanine to form guanylcobamide, as demonstrated with 8-14C-guanine. Addition of adenine did not lead to the formation of adenylcobamide (pseudovitamin B12), whereas 5,6-dimethylbenzimidazole was transformed into vitamin B12.

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Guimarães, D.H., Weber, A., Klaiber, I. et al. Guanylcobamide and hypoxanthylcobamide-Corrinoids formed by Desulfovibrio vulgaris . Arch. Microbiol. 162, 272–276 (1994). https://doi.org/10.1007/BF00301850

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  • DOI: https://doi.org/10.1007/BF00301850

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