Abstract
The activity of chitin synthase extracted from whole cells of Saccharomyces cerevisiae shows reproducible changes during the course of batch cultivation. During exponential growth 5–10% of the enzyme occurs in the active form, whereas in the stationary phase no active enzyme can be detected. Of three yeast proteinases, A, B and C, only B is able to activate pre-chitin synthase and inactivate chitin synthase. A new model of the regulation is presented which accounts for the specific location as well as for termination of chitin synthesis during the budding cycle.
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These results were reported at the 4th International Symposium on Yeasts in Vienna, July 1974, and are part of doctoral thesis by A.H., University Freiburg (1974).
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Hasilik, A. Inactivation of chitin synthase in Saccharomyces cerevisiae . Arch. Microbiol. 101, 295–301 (1974). https://doi.org/10.1007/BF00455946
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DOI: https://doi.org/10.1007/BF00455946