Abstract
After two injections of urethane in a dose of 1 mg/g adenomas of the lungs developed in 2 of 10 nude mice and in 7 of 10 normal animals from the same litter. The mean number of adenomas per mouse was 0.2±0.13 and 1.2±0.36 respecitvely (p<0.05).
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Kaledin, V.I., Gruntenko, E.V. & Morozkova, T.S. Lower carcinogenicity of urethane for the lungs of athymic nude mice than for immunologically normal mice of the same litters. Bull Exp Biol Med 86, 1490–1492 (1978). https://doi.org/10.1007/BF00800294
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DOI: https://doi.org/10.1007/BF00800294