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Is the abnormal reaction of lymphocytes of patients with atopic bronchial asthma to adenosine a component of pathogenesis or a compensatory reaction?

  • Experimental Methods for Clinical Practice
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

After a 30-min incubation in the presence of adenosine, the suppressor activity of peripheral blood lymphocytes from healthy subjects decreases as well as the count of CD4+ cells, while the count of CD8+ cells increases. The suppressor activity of peripheral blood lymphocytes from patients with atopic bronchial asthma and the count of CD8+ cells increase after a 16-h incubation with adenosine, while a 30-min incubation enhances the expression of CD4 antigen.

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References

  1. A. Yu. Baryshnikov,Gematol. Transfuziol., No. 8, 4–7 (1990).

    Google Scholar 

  2. Yu. B. Belousov, P. V. Sergeev, V. V. Omel'yanovskii,et al., Ter. Arkh.,64, No. 3, 58–60 (1992).

    PubMed  Google Scholar 

  3. K. G. Gvelesiani,Vopr. Okhr. Mat.,18, No. 5, 84–85 (1973).

    Google Scholar 

  4. L. L. Ioshpa,Ibid.,,13, No. 2, 41–45 (1968).

    CAS  Google Scholar 

  5. G. V. Poryadin, Zh. M. Salmasi, E. A. Busarova, and N. E. Zhuravleva,Pat. Fiziol., No. 4, 33–36 (1993).

    Google Scholar 

  6. G. V. Poryadin, Zh. M. Salmasi, and L. V. Koval'chuk,Immunologiya, No. 5, 64–67 (1980).

    Google Scholar 

  7. A. V. Kharitonova and T. L. Kvashina,Pediatriya, No. 10, 29–31 (1976).

    Google Scholar 

  8. J. Alberola-Ila, F. Lozano, L. Places,et al., Immunologia,8, No. 3, 95–101 (1989).

    Google Scholar 

  9. W. E. Biddison and S. Shaw,Immunol. Rev.,109, 5–15 (1989).

    Article  PubMed  CAS  Google Scholar 

  10. A. Boyum,Scand. J. Clin. Lab. Invest. Suppl.,21, 9–109 (1968).

    Article  CAS  Google Scholar 

  11. M. K. Church and S. T. Holgate,Trends Pharmacol. Sci.,7, No. 2, 49–50 (1986).

    Article  Google Scholar 

  12. J. P. Di-Santo, J. S. Klein, and N. Flomenberg,Immunogenetics,30, No. 6, 494–501 (1989).

    Article  CAS  Google Scholar 

  13. G. M. Kammer, J. Smith, and R. Mitchell,J. Immunol.,130, No. 1, 38–44 (1983).

    PubMed  CAS  Google Scholar 

  14. F. A. Mateos, P. F. Gomez, I. G. Puig,et al., Adv. Exp. Med. Biol.,253A, 333–338 (1989).

    PubMed  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Russian State Medical University, Moscow

    G. V. Poryadin, A. I. Makarkov, E. V. Gavrilova & Zh. M. Salmasi

Authors
  1. G. V. Poryadin
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  2. A. I. Makarkov
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  3. E. V. Gavrilova
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  4. Zh. M. Salmasi
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 122, No. 10, pp. 474–477, October, 1996

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Poryadin, G.V., Makarkov, A.I., Gavrilova, E.V. et al. Is the abnormal reaction of lymphocytes of patients with atopic bronchial asthma to adenosine a component of pathogenesis or a compensatory reaction?. Bull Exp Biol Med 122, 1062–1065 (1996). https://doi.org/10.1007/BF02447038

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  • DOI: https://doi.org/10.1007/BF02447038

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