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DNA-hydrolyzing antibodies in lymphoproliferative diseases

  • Experimental Methods for Clinical Practice
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Natural catalytic antibodies are known to be autoantibodies and are found in patients with different autoimmune diseases. The production of catalytic autoantibodies against DNA is demonstrated for a number of lymphoproliferative diseases. The statistical analyses performed show that this production is related to the chronic proliferation of mature B lymphocytes and correlates with the corresponding autoimmune disorders.

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Authors and Affiliations

  1. Laboratory of the Chemical Bases of Biocatalysis, Institute of Molecular Biology, Russian Academy of Medical Sciences, Moscow

    A. V. Kozyr', A. V. Kolesnikov, E. I. Yakhnina, I. A. Astsaturov, E. Yu. Varlamova, E. V. Kirillov & A. G. Gabibov

  2. Department of Hematology and Intensive Care, All-Russian Hematological Research Center, Russian Academy of Medical Sciences, Moscow

    A. V. Kozyr', A. V. Kolesnikov, E. I. Yakhnina, I. A. Astsaturov, E. Yu. Varlamova, E. V. Kirillov & A. G. Gabibov

Authors
  1. A. V. Kozyr'
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  2. A. V. Kolesnikov
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  3. E. I. Yakhnina
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  4. I. A. Astsaturov
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  5. E. Yu. Varlamova
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  6. E. V. Kirillov
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  7. A. G. Gabibov
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Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, No 2, pp. 204–206, February, 1996

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Kozyr', A.V., Kolesnikov, A.V., Yakhnina, E.I. et al. DNA-hydrolyzing antibodies in lymphoproliferative diseases. Bull Exp Biol Med 121, 189–191 (1996). https://doi.org/10.1007/BF02446633

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  • DOI: https://doi.org/10.1007/BF02446633

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