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Comparison between radioimmunoanalysis and Mancini methods for a case of ascorbic acid radioprotection on rats contaminated with tritiated water

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Abstract

The recovery of humoral immune response has been comparatively studied by a radioimmunoanalysis (RIA) method and by Mancini single immunoradial diffusion method in an experiment consisting in chronic contamination with low doses of tritiated water (HTO) and oral administration of high doses of ascorbic acid on rats as radioprotector. The radioprotective effect of ascorbic acid was found to be dependent both on the radiation dose and the amount of ascorbic acid administered.

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Bejan, A., Maican, A. & Turcu, G. Comparison between radioimmunoanalysis and Mancini methods for a case of ascorbic acid radioprotection on rats contaminated with tritiated water. Journal of Radioanalytical and Nuclear Chemistry Letters 201, 199–204 (1995). https://doi.org/10.1007/BF02164827

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  • DOI: https://doi.org/10.1007/BF02164827

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