Abstract
Biologically active nitrogen heterocycles (1–7) containing ferrocene and quinuclidine fragments were synthesized. 3-Methylene-2-ferrocenylmethylenequinuiclidine forms adducts withN-phenylimides of azodicarboxylic (the structure was established by X-ray structural analysis) and malefic acids. 3-Methylene-2-fer-rocenylmethylenequinticlidine also undergoes [4+2]-cyclodimerization when heated and adds salts of the 3-methyl-2-ferrocenylmethyleneI-azoniabicyclo[2.2.2]oct-3-yl cation at the terminal methylene group to form a linear addition product.
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Instituto de Quimica, Universidad Nacional Autonoma de Mexico (UNAM), Circuito Exterior, Ciudad Universitaria, Coyoacan.
Translated fromIzvestiya Akademii Nauk, Seriya Khimicheskaya, No. 11, pp 2743–2750, November, 1996.
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Klimova, E.I., Ruiz Ramirez, L., Martinez Garcia, M. et al. Synthesis of biologically active compounds based on 2-ferrocenylmethylene-3-quinuclidone. Russ Chem Bull 45, 2602–2609 (1996). https://doi.org/10.1007/BF01431126
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DOI: https://doi.org/10.1007/BF01431126