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Surface alkaline hydrolysis of 2-hydroxyethyl methacrylate gels

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Abstract

The surface modification of glycol methacrylate intraocular lenses by selective alkaline hydrolysis was studied in order to find the conditions for improvement in biocompatibility and simultaneous preservation of good optical properties of these gels. It was found that the thickness of the modified layer can be influenced by the reaction temperature, NaOH concentration and reaction time. Using at least 30% NaOH, short reaction times and temperatures of at least 90°C, lenses with good optical properties and with carboxylic groups in the surface layer were prepared. The method may be useful for obtaining hydrophilic medical materials with improved properties and increased biocompatibility.

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Authors and Affiliations

  1. Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, 16206, Prague 6, Czech Republic

    S. Ševčík, J. Vacík & D. Chmelíková

  2. Department of Anatomy, 1st Faculty of Medicine, Charles University, 12800, Prague 2, Czech Republic

    K. Smetana Jr

Authors
  1. S. Ševčík
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  2. J. Vacík
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  3. D. Chmelíková
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  4. K. Smetana Jr
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Ševčík, S., Vacík, J., Chmelíková, D. et al. Surface alkaline hydrolysis of 2-hydroxyethyl methacrylate gels. J Mater Sci: Mater Med 6, 505–509 (1995). https://doi.org/10.1007/BF00151030

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  • DOI: https://doi.org/10.1007/BF00151030

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