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On the constitution of reserpine fromRauwolfia serpentina benth

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Zusammenfassung

Bei der Permanganatoxydation und der Kalischmelze der Reserpinsäure wurden 4-Methoxy-oxalylanthranilsäure und 5-Oxyisophtalsäure isoliert. Als Arbeitshypothese wird deshalb für Reserpinsäure eine Yohimbanstruktur postuliert. Durch die obigen Abbauergebnisse ist die Stellung der einen Methoxylgruppe festgelegt, wogegen die Haftstellen der drei weiteren funktionellen Gruppen noch nicht gesichert sind.

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References

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Authors and Affiliations

  1. Research Laboratories of Ciba Pharmaceutical Products, Inc., Summit, New Jersey

    L. Dorfman, C. F. Huebner, H. B. MacPhillamy, E. Schlittler & A. F. St.André

Authors
  1. L. Dorfman
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  2. C. F. Huebner
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  3. H. B. MacPhillamy
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  4. E. Schlittler
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  5. A. F. St.André
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Additional information

Communication 7 onRauwolfia Alkaloids.

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Dorfman, L., Huebner, C.F., MacPhillamy, H.B. et al. On the constitution of reserpine fromRauwolfia serpentina benth. Experientia 9, 368–369 (1953). https://doi.org/10.1007/BF02167633

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