Summary
A new glycoprotein of 31,500 dalton, which has a high affinity for ouabain, and is independent of (Na+−K+)-ATPase, was solubilized from transverse tubule membrane and junctional sarcoplasmic reticulum complexes (TTM-JSR) of cat cardiac muscle. This protein could be extracted only in small amounts from sarcolemmaplasma membrane (SLM-PL) fragments, suggesting that it indeed originates from the TTM-JSR.
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References
Fujino, S., Tanaka, M., and Fujino, M., Nature223 (1969) 413.
Godfraind, T., and Ghysel-Burton, J., Nature265 (1977) 165.
Allen, D. G., and Blinks, J. R., Nature237 (1978) 509.
Fujino, S., Igarashi, T., and Fujino, M., Jap. J. Pharmac.29 (1979) 839.
Fujino, S., and Fujino, M., Can. J. Physiol. Pharmac.58 (1979) 712.
Fujino, S., and Fujino, M., Jap. J. Pharmac.30 (1980) 711.
Erdmann, E., Philipp, G., and Scholz, H., Biochem. Pharmac.29 (1980) 3219.
Adams, R. J., Schwarz, A., Grupp, G., Grupp, I., Lee, S. W., and Wallick, E. T., Nature296 (1982) 167.
Fujino, S., and Fujino, M., Can. J. Physiol. Pharmac.60 (1982) 542.
Lichtstein, D., and Samuelov, S., Proc. natl. Acad. Sci. USA79 (1982) 1453.
Kim, D., Barry, W. H., and Smith, T. W., J. Pharmac. exp. Ther.231 (1984) 326.
Hamlyn, J. M., Cohen, N., and Blaustein, M. P., Circulation68 (1983) III-63, No. 249.
Noel, F., and Godfraind, T., Biochem. Pharmac.33 (1984) 47.
Grupp, I., Im, W.-B., Lee, C. O., Lee, S.-W., Pecker, M. S., and Schwarz, A., J. Physiol., Lond.360, (1985) 149.
Allen, D. A., Eisner, D. A., and Wray, S. C., Nature316 (1985) 674.
Rasmussen, H. H., Ten Eick, R. E., Okita, G. T., Hartz, R. S., and Singer, D. H., J. Pharmac. exp. Ther.235 (1985) 629.
Ebashi, S., A. Rev. Physiol.38 (1976) 293.
Endo, M., Physiol. Rev.57 (1977) 71.
Fujino, S., Kawagishi, S., Eguchi, S., and Tanaka, M., Jap. J. Pharmac.21 (1971) 423.
Laemmli, U. K., Nature227 (1970) 680.
Forbush III, B., and Hoffman, J. F., Biochim. biophys. Acta555 (1979) 299.
Page, M., Can. J. Biochem.51 (1973) 1213.
Rohringer, R., and Holden, D. W., Analyt. Biochem.144 (1985) 118.
Fujino, S., Izumi, T., Kawagishi, S., and Tanaka, M., Jap. J. Pharmac.19 (1969) 170.
Shull, G. E., Schwarz, A., and Lingrel, J. B., Nature316 (1985) 691.
Rogers, T. B., and Lazdunski, M., Biochemistry18 (1979) 135.
Goeldner, M. P., Hirth, C. G., Rossi, B., Ponzio, G., and Lazdunski, M., Biochemistry22 (1983) 4685.
Fujino, M., Sato, Y., Arima, T., and Takai, J., J. Physiol. Soc. Japan46 (1984) 469.
Fujino, M., Arima, T., and Sato, Y., Proc. int. Union physiol. Sci.16 (1986) 270.
Fujino, S., Satoh, K., Kurokawa, T., Bandoh, T., and Takashima, K., Proc. int. Union physiol. Sci.16 (1986) 354.
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Fujino, S., Satoh, K., Bando, T. et al. Solubilization and characterization of a ouabain-sensitive protein from transverse tubule membranejunctional sarcoplasmic reticulum complexes (TTM-JSR) in cat cardiac muscle. Experientia 45, 466–469 (1989). https://doi.org/10.1007/BF01952032
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DOI: https://doi.org/10.1007/BF01952032