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Effect of thyroid hormone on somatomedin-C release from perfused rat liver

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Summary

The effect of thyroid hormone on plasma somatomedin-C (SmC) level and on SmC release from perfused rat liver was investigated. Plasma SmC levels and liver tissue SmC were significantly increased in thyroxine-treated rats. Physiological doses of triiodothyronine increased SmC release and SmC concentration in the perfused rat liver. These results indicate that thyroid hormone directly enhances the synthesis and release of SmC in the rat.

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References

  1. Baxter, R. C., Shane Brown, A., and Turtle, J. R., Clin. Chem.283 (1982) 488.

    Article  Google Scholar 

  2. Chernausek, S. D., Underwood, L. E., Utiger, R. D., and Van Wyk, J. J., Clin. Endocr.19 (1983) 334.

    Article  Google Scholar 

  3. Blows, J. A., Morrell, D. J., Taylor, A. M., and Holder, A. T., IRCS Med. Sci.12 (1984) 759.

    CAS  Google Scholar 

  4. Gaspard, T., Wondergen, R., Hamandzic, M., and Klitgaar, H. M., Endocrinology102 (1978) 606.

    Article  CAS  PubMed  Google Scholar 

  5. Binoux, M., Faivre-Bauman, A., Lassarre, C., and Tixier Vidal, A., Devl Brain. Res.21 (1985) 319.

    Article  CAS  Google Scholar 

  6. Phillips, L. S., and Unterman, T. G., Clin. Endocr. Metab.13 (1984) 145.

    Article  CAS  Google Scholar 

  7. Ikeda, T., Takeuchi, T., Ito, Y., Murakami, I., Mokuda, O., Tominaga, M., and Mashiba, H., Am. J. Physiol.251 (1986) E 660.

    CAS  Google Scholar 

  8. Sugano, T., Suda, K., Shimada, M., and Oshino, N., J. Biochem.83 (1978) 995.

    Article  CAS  PubMed  Google Scholar 

  9. Chopra, I. J., J. clin. Endocr. Metab.34 (1972) 938.

    Article  CAS  PubMed  Google Scholar 

  10. Chopra, I. J., Solomon, D. H., and Beal, G. N., J. clin. Invest.50 (1971) 2033.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. D'Ercole, A. J., Stiles, A. D., and Underwood, L. E., Proc. natl Acad. Sci. USA81 (1984) 935.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Zapf, J., Walter, H., and Froesch, E. R., J. clin. Invest.68 (1981) 1321.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Vassilopolou-Sellin, R., and Phillips, L. S., Endocrinology110 (1982) 582.

    Article  Google Scholar 

  14. Cavaliere, H., Knobel, M., and Medeiros-Neto, G., Hormone Res.25 (1987) 132.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. The First Department of Internal Medicine, Tottori University School of Medicine, Nishi-machi 36-1, 683, Yonago, Japan

    T. Ikeda, K. Fujiyama, T. Takeuchi, M. Honda, O. Mokuda, M. Tominaga & H. Mashiba

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  1. T. Ikeda
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  2. K. Fujiyama
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  3. T. Takeuchi
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  4. M. Honda
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  5. O. Mokuda
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  6. M. Tominaga
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  7. H. Mashiba
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Ikeda, T., Fujiyama, K., Takeuchi, T. et al. Effect of thyroid hormone on somatomedin-C release from perfused rat liver. Experientia 45, 170–171 (1989). https://doi.org/10.1007/BF01954863

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  • DOI: https://doi.org/10.1007/BF01954863

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