Summary
Atrial natriuretic factor (ANF) is released in response to many stimuli which increase right atrial pressure. Following hemorrhage pigs lowered their atrial pressures, developed a tachycardia and increased ANF levels. Electrical pacing increased heart rate and ANF levels. There is a stimulus to ANF release other than atrial stretch, probably heart rate.
Similar content being viewed by others
References
Lang, R. E. et al., Atrial natriuretic factor — a circulating hormone stimulated by volume loading. Nature314 (1985) 264.
Bates, E. R., Shenker, Y., and Grekin, R. J., The relationship between plasma levels of immunoreactive atrial natriuretic hormone and hemodynamic function in man. Pathophysiol. nat. Hist.73 (1986) 1155.
Burnett, J. C. et al., Atrial natriuretic peptide elevation in congestive heart failure in the human. Science231 (1986) 1145.
Manning, P. T., Schwartz, D., Katsube, N. C., Holmberg, S. W., and Needleman, P., Vasopressin-stimulated release of atriopeptin: endocrine antagonists in fluid homeostasis. Science229 (1985) 395.
Schiffrin, E. L., Gutkowska, J., Kuchel, O., Cantin, M., and Genest, J., Plasma concentration of atrial natriuretic factor in a patient with paroxysmal atrial tachycardia. New Engl. J. Med.229 (1985) 1196.
Yamaji T. et al., Possible role for atrial natriuretic peptide in polyuria associated with paroxysmal atrial arrhythmias. Lancet229 (1985) 1211.
Wood, P., Polyuria in paroxysmal tachycardia and paroxysmal atrial flutter and fibrillation. Br. Heart J.25 (1963) 273.
Gutkowska, J., Thibault, G., Januszewicz, P., Cantin, M., and Genest, J., Direct radioimmunoassay of atrial natriuretic factor. Biochem. biophys. Res. Commun.122 (1984) 593.
Napier, N. A., Vandlen, R. L., Albert-Schonberg, G. et al., Specific membrane receptors for atrial natriuretic factor in renal and vascular tissues. Proc. natl Acad. Sci. USA81 (1984) 5946.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ziegler, M.G., Shackford, S.R., Wilner, K.D. et al. Atrial natriuretic factor in hypovolemic tachycardia. Experientia 43, 1021–1022 (1987). https://doi.org/10.1007/BF01952226
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01952226