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Granulocyte adhesion to nephritic glomeruli through recognition of activated C4 and C3 in immune deposits

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Summary

Sections of rat kidney with bovine serum albumin nephritis were incubated either with a single component of complement or with several components in sequence and then reacted with granulocytes. The average number of granulocytes bound to a nephritic glomerulus was elevated in sections incubated with C4 or C3 and increases were most significant when C14, C142 or C1423 were incubated.

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Authors and Affiliations

  1. Dept of Immunology (IMMS), Scripps Clinic and Research Foundation, 10666 North Torrey Pines Road, 92037, La Jolla, CA, USA

    T. Yamamoto & I. Kihara

  2. Department of Pathology, Institute of Nephrology, Niigata University School of Medicine, Asahimachidori 1, 951, Niigata, Japan

    T. Yamamoto, S. Miyazaki, K. Kawasaki & E. Yaoita

Authors
  1. T. Yamamoto
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  2. S. Miyazaki
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  3. K. Kawasaki
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  4. E. Yaoita
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  5. I. Kihara
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Yamamoto, T., Miyazaki, S., Kawasaki, K. et al. Granulocyte adhesion to nephritic glomeruli through recognition of activated C4 and C3 in immune deposits. Experientia 41, 1456–1457 (1985). https://doi.org/10.1007/BF01950033

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  • DOI: https://doi.org/10.1007/BF01950033

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