Summary
Metabolic studies in which3H-sitosterol,3H-stigmasterol, and14C-desmosterol were administered by feeding and injection to the khapra beetle,Trogoderma granarium Everts, provided strong evidence that this insect is unable to dealkylate phytosterols and convert them to cholesterol.
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References
J.A. Svoboda, A.M.G. Nair, Nita Agarwal, H.C. Agarwal and W.E. Robbins, Experientia35, 1454 (1979).
J.A. Svoboda, M.J. Thompson, W.E. Robbins, and T.C. Elden, Lipids10, 524 (1975).
J.A. Svoboda, S.R. Dutky, W.E. Robbins and J.N. Kaplanis, Lipids12, 318 (1977).
The [2,4-3H]-sitosterol and [2,4-3H]-stigmasterol were prepared according to: M.J. Thompson, O.W. Berngruber and P.D. Klein, Lipids6, 233 (1971); [26-14C]-desmosterol was purchased from New England Nuclear, Boston, MA.
H.C. Agarwal, J. Insect Physiol.16, 2023 (1970).
Mention of a company name or proprietary product does not necessarily imply endorsement by the U.S. Department of Agriculture.
J.A. Svoboda, M.J. Thompson, T.C. Elden and W.E. Robbins, Lipids9, 752 (1974).
J.A. Svoboda, W.E. Robbins, C.F. Cohen and T.J. Shortino, in: Insect and Mite Nutrition, p. 505. Ed. J.G. Rodriguez. North Holland, Amsterdam 1972.
J.A. Svoboda, M.J. Thompson and W.E. Robbins, Life Sci.6, 395 (1967).
J.A. Svoboda, R.F.N. Hutchins, M.J. Thompson and W.E. Robbins, Steroids14, 469 (1969).
A.J. Clark and K. Bloch, J. biol. Chem.234, 2583 (1959).
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Svoboda, J.A., Nair, A.M.G., Agarwal, N. et al. Lack of conversion of C29-phytosterols to cholesterol in the khapra beetle,Trogoderma granarium Everts. Experientia 36, 1029–1030 (1980). https://doi.org/10.1007/BF01965949
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DOI: https://doi.org/10.1007/BF01965949