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Effect of growth factors on hepatic drug metabolism in diabetic-hypophysectomized rats

  • Specialia
  • Endocrinologica
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Summary

In vivo administration to diabetic-hypophysectomized rats of either the growth factor produced by the plerocercoid larvae of the tapeworm, Spirometra mansonoides, or mammalian growth hormone caused inhibition of hepatic drug metabolism measured in vitro.

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References

  1. D. E. Cook and C. K. Phares, Biochem. Pharmac.24, 1919 (1975).

    Article  CAS  Google Scholar 

  2. E. Wei and J. T. Wilson, J. Pharmac. exp. Ther.177, 227 (1971).

    CAS  Google Scholar 

  3. R. L. Dixon, L. G. Hart and J. R. Fouts, J. Pharmac. exp. Ther.133, 7 (1961).

    CAS  Google Scholar 

  4. R. L. Dixon, L. G. Hart, L. A. Rogers and J. R. Fouts, J. Pharmac. exp. Ther.142, 312 (1963).

    CAS  Google Scholar 

  5. T. J. Merimee and D. Rabin, Metabolism22, 1235 (1973).

    Article  CAS  PubMed  Google Scholar 

  6. A. Hyrärinen and E. A. Nikkila, Clinica chem. Acta7, 140 (1963).

    Article  Google Scholar 

  7. J. F. Mueller, J. Parasit.55, 167 (1968).

    Article  Google Scholar 

  8. C. R. Morgan, and A. Lazarow, Diabetes14, 669 (1965).

    Article  CAS  PubMed  Google Scholar 

  9. R. O. Scow, Endocrinology61, 582 (1957).

    Article  CAS  PubMed  Google Scholar 

  10. W. R. Ruegamer and J. F. Mueller, J. Nutr.103, 1496 (1973).

    Article  CAS  PubMed  Google Scholar 

  11. D. R. Harlow, W. Mertz and J. F. Mueller, J. Parasit.53, 449 (1967).

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Biochemistry, University of Nebraska Medical Center, 68105, Omaha, Nebraska, USA

    D. E. Cook & C. K. Phares

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  1. D. E. Cook
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  2. C. K. Phares
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Cook, D.E., Phares, C.K. Effect of growth factors on hepatic drug metabolism in diabetic-hypophysectomized rats. Experientia 33, 1110–1111 (1977). https://doi.org/10.1007/BF01946000

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  • DOI: https://doi.org/10.1007/BF01946000

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