Summary
The depressor effects of natural and synthetic ACTH peptides were demonstrated in the rat. This is an extra-adrenal action of ACTH and is not related to the adrenal-stimulating or melanocyte-stimulating activity of the peptide.
Similar content being viewed by others
References
M. Ueda, S. Matsuda, M. Kawakami andH. Takeda, Jap. J. Pharmac.20, 585 (1970).
R. D. Bunag andE. Riley, J. appl. Physiol.36, 621 (1974).
Aib: α-aminoisobutyric acid.
M. Nakamura, A. Tanaka, M. Hirata andS. Inoue, Endocr. jap.19, 383 (1972).
M. Nakamura andA. Tanaka, Endocr. jap.19, 395 (1972).
A. Tanaka, Endocr. jap.18, 155 (1971).
M. Nakamura, J. Biochem.71, 1029 (1972).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Nakamura, M., Matsuda, S., Ueda, M. et al. Depressor effect of synthetic peptides related to ACTH on blood pressure in rats. Experientia 32, 368–369 (1976). https://doi.org/10.1007/BF01940843
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01940843