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Iproniazid interaction with the H3 norepinephrine uptake and retention, on isolated left atrium of guinea-pig

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Resumen

La incorporación de H3NE a la auricula aislada de cobayo reserpinizado, tratado con Iproniazida (IPN) y atmosfera de Nitrogeno, es superior a la de sus controles sin IPN. En auriculas no reserpinizadas, la IPN aparece como agente bloquenate de la incorporación. Se sugiere que este bloqueo ocurre a nivel de las vesiculas especificas de almacenamiento presentes en las terminaciones nerviosas adrenergicas.

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Literatur

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Authors and Affiliations

  1. Departamento de Farmacologia, Facultad de Medicina, Ciudad Universitaria, Madrid 3, Spain

    R. Martinez-Sierra, A. Velasco-Martin & P. D. Garcia de Jalon

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  1. R. Martinez-Sierra
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  2. A. Velasco-Martin
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  3. P. D. Garcia de Jalon
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Martinez-Sierra, R., Velasco-Martin, A. & Garcia de Jalon, P.D. Iproniazid interaction with the H3 norepinephrine uptake and retention, on isolated left atrium of guinea-pig. Experientia 29, 568–570 (1973). https://doi.org/10.1007/BF01926669

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