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Zur kompensatorischen Nierenregeneration. Autoradiographische Untersuchungen nach3H-Thymidin-Dauerinfusion

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  • Pharmacologica
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Summary

By continuous infusion of3H-thymidine, autoradiographic studies were performed to compare cellular proliferation in the compensatory regenerating kidney of rats after contralateral nephrectomy or contralateral temporal (1 h) ischaemia with physiological cell renewal in controls. Under each experimental condition, the highest labelling index is observed within the stratum labyrinthicum and then a gradual decrease occurs from there to the stratum subcorticale, zona intermedia and basalis. As to the topic of DNA synthesizing cells in the different zones of the kidney, there are only quantitative differences between physiological cell renewal of the controls and compensatory regeneration following contralateral nephrectomy and contralateral ischaemia.

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References

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Authors and Affiliations

  1. Pathologisches Institut der Universität, 87 Würzburg, Deutschland

    E. Stöcker, E. Neumann-Redlin & W. -D. Heine

Authors
  1. E. Stöcker
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  2. E. Neumann-Redlin
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  3. W. -D. Heine
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Mit Unterstützung der Deutschen Forschungsgemeinschaft.

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Stöcker, E., Neumann-Redlin, E. & Heine, W.D. Zur kompensatorischen Nierenregeneration. Autoradiographische Untersuchungen nach3H-Thymidin-Dauerinfusion. Experientia 24, 463–464 (1968). https://doi.org/10.1007/BF02144393

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  • DOI: https://doi.org/10.1007/BF02144393

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