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Azione dell'«Epidermal Growth Factor» sulla sintesi di acidi nucleici e proteine dell'epitelio cutaneo

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Summary

The biological effect has been investigated of a specific protein with a growth-stimulating activity on epidermal cells.

Injection of minute amounts of this factor (EGF) into newborn rats produces hyperplasia of the epidermis with a marked increase in the protein and nucleic acid content per unit of skin area. The activity of a number of epidermal enzymes per unit area is also increased by the epidermal growth factor.

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References

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Authors and Affiliations

  1. Istituto Superiore di Sanità, Laboratori di Chimica Biologica e Facoltà di Medicina e Chirurgia, Università Cattolica S. Cuore, Roma, Italia

    P. U. Angeletti, M. L. Salvi, R. L. Chesanow & S. Cohen

Authors
  1. P. U. Angeletti
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  2. M. L. Salvi
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  3. R. L. Chesanow
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  4. S. Cohen
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Additional information

Il presente lavoro è stato realizzato con fondi del NIH e della Merck Sharp-Dohme Co.

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Angeletti, P.U., Salvi, M.L., Chesanow, R.L. et al. Azione dell'«Epidermal Growth Factor» sulla sintesi di acidi nucleici e proteine dell'epitelio cutaneo. Experientia 20, 146–148 (1964). https://doi.org/10.1007/BF02150704

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  • DOI: https://doi.org/10.1007/BF02150704

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