Summary
It is demonstrated that the acetylation of sulfanilamide and of p-amino-azobenzene, in the presence of pigeon liver extract and coenzyme A, is not only inhibited by α-phenyl fatty acids but also by a considerable number of other substances. The most effective inhibitors contain at least two benzene nuclei and one acidic group (phenolic hydroxyl or a carboxyl group).
References
J. Cottet undJ. Redel, C. r. Acad. Sci.236, 2553 (1953).
J. Cottet, A. Mathivat undJ. Redel, Pr. méd.62, 939 (1954).
C. A. Rossi undF. Sanguinetti, Giorn. Bioch.4, 240, 385 (1955); ref. in: Chem. Abstr.50, 7912i, 11842 f (1956).
G. Milhaud undJ. P. Aubert, Exper.12, 99 (1956).
S. Garratini et al. Boll. Soc. ital. Biol. sper.31, 1653 (1955).
G. Cavallini undE. Massarini, Farmaco, ed. sc.11, 167 (1956).
S. Garratini, C. Morpurgo undN. Passerini, Exper.12, 317 (1956).
G. Annoni, Farmaco, ed. sc.11, 244 (1956).
N. O. Kaplan undF. Lipmann, J. biol. Chem.174, 37 (1948).
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Wagner-Jauregg, T. Hemmung der Azetylierungsfunktion des Coenzyms A. Experientia 13, 277–279 (1957). https://doi.org/10.1007/BF02158414
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DOI: https://doi.org/10.1007/BF02158414