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Über eine selektive Mitosehemmung und -schädigung bei jungen Ratten durch Synthalin A

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Summary

A single subcutaneous injection of synthalin-A does not affect the cytoplasma ofA-cells in pancreatic islets of the rat during the 1st–5th day of life, in contrast to adult animals. Selective action was found on mitoticA-cells: reduction of mitotic frequency to 25% of the normal rate, and pathological mitoses in the sense of the so-called primary effect. The mitoses ofB-cells, exocrine pancreatic cells and intestinal epithelia seemed to be unchanged, although the mitotic rate was higher than inA-cells.

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Authors and Affiliations

  1. Aus dem Anatomischen Institut der Universität Hamburg und der Universitäts-Frauenklinik Hamburg-Eppendorf, Germany

    W. Runge & H. Heinrich

Authors
  1. W. Runge
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  2. H. Heinrich
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Runge, W., Heinrich, H. Über eine selektive Mitosehemmung und -schädigung bei jungen Ratten durch Synthalin A. Experientia 11, 489–491 (1955). https://doi.org/10.1007/BF02166834

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  • DOI: https://doi.org/10.1007/BF02166834

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