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A site of action of light on14C-acetate incorporation into human skin sterols

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Zusammenfassung

Die Synthese von Sterolen in menschlicher Haut, welche im langwelligen Spektralbereich bestrahlt worden war, wurde mit radioaktiv markiertem Acetyl-Co A, Acetat and Pyruvat geprüft. Von Acetyl-Co A konnte nur geringe Hemmung nachgewiesen werden, während Licht eine merkbare Hemmung von Acetat und Pyruvatinkorporation verursachte. Die Resultate lassen vermuten dass die Acetataktivierung die von Licht beeinflussbare Stufe in der Biosynthese von Sterolen ist.

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Authors and Affiliations

  1. Veterans Administrations Hospital and Departments of Dermatology and Biochemistry, Baylor College of Medicine, 77031, Houston, Texas, USA

    H. S. Black, J. D. Smith, B. J. Cumbus & W. B. Lo

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  1. H. S. Black
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  2. J. D. Smith
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  3. B. J. Cumbus
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  4. W. B. Lo
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Black, H.S., Smith, J.D., Cumbus, B.J. et al. A site of action of light on14C-acetate incorporation into human skin sterols. Experientia 28, 1023–1025 (1972). https://doi.org/10.1007/BF01918648

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  • DOI: https://doi.org/10.1007/BF01918648

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