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Hypoxic inactivation of cold-induced brown fat thermogenesis

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Résumé

Chez des rats adaptés au froid, non anesthésiés, placés brièvement dans une atmosphère de 12% d'oxygène, on observer un arrêt immédiat de la thermogénèse de la graisse brune. Cet effet semble s'expliquer par l'absence d'activation par le système sympathique. L'absence d'une réaction de thermogénèse en réponse à une injection de noradrénaline chez des rats soumins au froid et dans des conditions hypoxiques plaide en faveur de cette explication.

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Literatur

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Authors and Affiliations

  1. Department of Physiological Sciences, University of California, 95616, Davis, (California), (USA)

    D. D. Schnakenberg & R. A. Hoffman

Authors
  1. D. D. Schnakenberg
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  2. R. A. Hoffman
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Additional information

Supported by research grant NASA No. NGR-05-004-035. The counsel and assistance given by Dr.R. Em. Smith, Dr.J. M. Horowitz and Dr.B. A. Horwitz is gratefully acknowledged.

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Schnakenberg, D.D., Hoffman, R.A. Hypoxic inactivation of cold-induced brown fat thermogenesis. Experientia 28, 1172–1173 (1972). https://doi.org/10.1007/BF01946150

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  • DOI: https://doi.org/10.1007/BF01946150

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