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Biomedicine

Current Issue

  • Open Access
  • Case Report

Spontaneous bruising in an elderly female

 

 Celia Soni Saldanha1, Ravina Surve2, Shrutakirthi Shenoi2, Rama Prakash S.3, Meghashree G.2 

2024, 44(1), 164-166, 10.51248/.v44i1.4037, May 1, 2024

 

 Bruising in the elderly can be relatively common due to changes in the skin and blood vessels that occur with aging. Several factors such as skin changes, medications, comorbidities contribute to an increased susceptibility to bruising in older individuals. While mild brui…

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  • Open Access
  • Case Series

Diagnostic spectrum of cysts of head and neck: Case series and review of literature

 

 Rukma Bhandary, Deepalakshmi Tanthry, Poojitha S., Basavaprakash Sheelavanth, Meghana Udaya Acharya 

 

2024, 44(1), 159-163, 10.51248/.v44i1.4035, May 1, 2024

 

One of the foremost problems that brings patients to Otorhinolaryngology clinics are cystic swellings in the head and neck region. We aimed to study the presentation, configuration of cystic swellings of head and neck for diagnosis and management. A retrospective study of 30 pat…

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  • Open Access
  • Original Article

Prevalence of anxiety among patients with a total knee replacement

 

 Bhavya Sharma, Vignesh Srinivasan, Prathap Suganthirababu, Kumaresan A., Jagadeesan Alagesan 

2024, 44(1), 154-158, 10.51248/.v44i1.4150, May 1, 2024

 

Introduction and Aim: Knee pain mainly attributed to osteoarthritis in the elderly, significantly impacts daily life. Non-surgical options include analgesics and physical therapy, but Total Knee Replacement (TKR) is most effective for severe cases. While complic…

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  • Open Access
  • Original Article

A comparative study of simple reaction time in PCOS and non-PCOS patients and its relation with BMI

 

 Preeti K.1, Priya S.A.1, Arun Gopi2, Kancherla Narasimha Abhinav Kaushal

2024, 44(1), 151-153, 10.51248/.v44i1.4052, May 1, 2024

 

Introduction and Aim: Polycystic ovarian syndrome (PCOS) is a hormonal disorder of the female reproductive system causing infertility, an irregular menstrual cycle, and hormonal imbalance characterized by hyperandrogenism. Reaction to any stimulus is a voluntary…

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  • Open Access
  • Original Article

Systemic and ocular pressure changes following sympathetic activation in yoga practitioners - A comparative study

Sudha B. Sreenivas1, Vinitha K. R.1,5, Ramya C. M.1, Arun Gopi2, Sreenivas M. R.3, Jishamol K. R.

2024, 44(1), 146-150, 10.51248/.v44i1.3440, Nov. 10, 2023

 

Introduction and Aim: Blood Pressure (BP), Intraocular Pressure (IOP) and Ocular Perfusion Pressure (OPP) are precursor parameters that lead to development of glaucoma. Under conditions of stress, either physical or psychological origin, there is disturbance of …

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  • Open Access
  • Original Article

Cytopathological study of pleural effusion in SARS-CoV2 RTPCR positive subjects during pandemic at tertiary care hospital

 

Sonali T. Advani1, Anita P. Javalgi, Vishwanath G. Shettar 

2024, 44(1), 140-145, 10.51248/.v44i1.3511, May 1, 2024

 

 Introduction and Aim: Respiratory system is the most common system affected by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).Review of literature reveals that pleural effusion were seen in one third of cases with Middle East Respiratory Syndr…

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  • Open Access
  • Original Article

A cross sectional study to assess the elevation in glucose regulated protein 78 levels in severe acute respiratory syndrome Coronavirus 2 infected patients and its correlation with metabolic conditions, severity, complications

 

Deepthi D’Souza1, Roopa Bhandary2, Reshma Kiran3, Pavithra K.2, Sushith3 

2024, 44(1), 136-139, 10.51248/.v44i1.4122, May 1, 2024

Introduction and Aim: COVID-19 pandemic has posed an exceptional challenge worldwide. Research encompassing newer diagnostic tests, targeted therapy has become the need of the hour. The objective of this work is to evaluate the levels of Glucose regulated protein 78 (GRP78) an E…

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  • Open Access
  • Original Article

Idiopathic sudden sensorineural hearing loss: A trial of modified Stennert’s infusion therapy

 

 Rukma Bhandary1, Mahesh S. G.1, Sapna M.1, Abhishek Sharma

2024, 44(1), 131-135, 10.51248/.v44i1.4038, May 1, 2024

 

 Introduction and Aim: Sudden sensorineural hearing loss presents as rapid onset hearing deterioration of more than 30dB within 72 hours at the minimum of three adjacent frequencies. The aim of this research was to determine the effect of Modified Stennert&…

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  • Open Access
  • Original Article

Variation of ABO phenotypes, Rhesus factor and salivary secretor status in chronic periodontitis patients with and without type II diabetes mellitus: A cross sectional study

Samjotha Dharma1, Sahana Purushotham1, Sreeraj Surendran

2024, 44(1), 125-130, 10.51248/.v44i1.3893, May 1, 2024

 

Introduction and Aim: While numerous studies have explored the connection between ABO blood groups and disease incidence in various medical contexts, there has been a scarcity of research dedicated to examining the relationship between ABO blood groups and the o…

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  • Open Access
  • Original Article

Impact of overburden due COVID-19 pandemic on psychological health and work efficacy of doctors in Mangalore city, Dakshina Kannada district -A cross-sectional study

 Carol Furtado1, Nitin Joseph2, Sushantha Perduru3, Maria Nelliyanil3, Manjula Anil4, Shreenidhi Shetty

2024, 44(1), 120-124, 10.51248/.v44i1.4153, May 1, 2024

 

Introduction and Aim: One of the greatest pandemics faced by the world was COVID-19 which has added increased strain and psychological impacts on healthcare workers. This study was conducted to find out the impact of overburden due to COVID-19 on the psychologic…

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  • Open Access
  • Original Article

An insight into immunohistochemical profile of triple negative breast carcinoma in a tertiary care center

M. Lauvanya1, G. Bhuvana2, K. Swaminathan3, M. Subarathi4
 

2024, 44(1), 114-119, 10.51248/.v44i1.4156, May 1, 2024

Introduction: Triple Negative Breast Cancer (TNBC) is a type of breast cancer that fails to express Estrogen Receptor (ER), Progesterone Receptor (PR) and Human Epidermal Growth Factor Receptor 2 (HER2) in Immunohistochemical analysis. TNBC has a unique molecular profile, aggres…

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  • Open Access
  • Original Article

The effect of ginger extract on expression of Gli1 and Patched-1 genes involved in breast cancer signaling pathway under in vitro condition

Seyedeh Mahsa Torabi1, Mahdi Rahaie2, Asa Ebrahimi1

2024, 44(1), 107-113, 10.51248/.v44i1.4152, May 1, 2024

Introduction and Aim: Breast cancer ranks among the leading causes of death in women worldwide. Ginger has shown potential efficacy against certain cancer types, surpassing conventional therapies such as chemotherapy and radiation. However, its molecular mechanisms remain less u…

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  • Open Access
  • Original Article

Relation of catecholamines with oxidative stress in patients undergoing cardiac surgery before and after endotracheal intubation

Sah R.K.1, More K.M.1, Sathe V.2

2024, 44(1), 101-106, 10.51248/.v44i1.2145, May 1, 2024

Introduction and Aim: Endotracheal intubation is used to maintain the airway open so that oxygen, medicine, or anesthesia can be administered. Anesthesia and surgery boost the release of cross-regulating hormones through physiological responses and psychological stress. There is…

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  • Open Access
  • Original Article

Exploring the association between PLGF and pregnancy outcomes

Nidhita M.N.1, Geetha Bhaktha2, Prashanth S.1

2024, 44(1), 98-100, 10.51248/.v44i1.4113, May 1, 2024

Introduction and Aim: Pregnancy demands vigilant fetal monitoring, yet traditional methods have limitations, leading to research on biomarkers like placental growth factor (PLGF) to enhance predictive accuracy for adverse outcomes. This investigation focuses on assessing the rel…

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  • Open Access
  • Original Article

A study on the prevalence and risk factors of coronary artery disease in patients with metabolic syndrome infected and not infected with COVID 19 from El- Oued (Algeria) region

Maroua Hammadi1, 2, Samir Derouiche1,2

 

2024, 44(1), 89-95, 10.51248/.v44i1.4123, May 1, 2024

Introduction and Aim: Coronary artery disease (CAD) is a pathological process described by atherosclerosis plaque in the epicardial arteries. CAD is a chronic process that begins during adolescence and slowly progresses through life. Several traditional risk factors genetics and…

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  • Open Access
  • Original Article

Alteration in the gastric microbiota of Erosive Reflux Disease and Non-erosive Reflux Disease patients: An indicator for disease progression

Aditya Vikram Singh1, Prateek Sharma 1, Kunal Das 2, Yogendra Bhaskar3, Isha Goel4, Harpreet Singh3, Rajashree Das1


 

2024, 44(1), 79-88, 10.51248/.v44i1.4154, May 1, 2024

Introduction and Aim: Erosive reflux disease (ERD) and Non-erosive reflux disease (NERD) are common gastrointestinal (GI) diseases in primary healthcare facilities that might result in alterations in gastric microflora. The aim was to characterize the altered composition of the …

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  • Open Access
  • Original Article

Molecular docking and dynamic studies of Indian blackberry in contrast to X-ray structure of human PPAR gamma

Aghil Soorya Aravindakshan1, Suraj Katole2, Sameer Sharma2, Susha Dinesh2, Manjula Shantaram3, Raghavendra L. S. Hallur4

 

2024, 44(1), 71-78, 10.51248/.v44i1.4116, May 1, 2024

Introduction and Aim: This study aims to elucidate the phytopharmacological and pharmacokinetic characteristics of Indian blackberries about human PPAR gamma receptors through in silico analyses. The protein receptor known as human PPAR gamma was retrieved, along with phytochemi…

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  • Open Access
  • Original Article

Evaluation of Uttroside B, a potent bioactive from Solanum nigrum Linn, as a candidate drug molecule against non-alcoholic fatty liver disease

Tennyson P. Rayginia1,2, Chenicheri K. Keerthana1,2, Sadiq C. Shifana1,3, Sreekumar U. Aiswarya1,4, Retnakumari Archana P1, Maria Joy P1, Ravi S. Lankalapalli4, Kuzhuvelil B. Harikumar1, Ruby John Anto1,3

 

2024, 44(1), 65-70, 10.51248/.v44i1.4066, May 1, 2024

Introduction and Aim: The incidence of non-alcoholic fatty liver disease is increasing steadily across the global population. NAFLD may progress to the more serious non-alcoholic steatohepatitis (NASH), a condition that can subsequently advance to fibrosis, cirrhosis, and in man…

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  • Open Access
  • Original Article

Bioproduction and characterization of melanin pigment produced by the fungal strain Gliocephalotrichum sp. DSGB2

Gowthami Anjaneya1, Santhosha B. Chandrappa1, Muthuraj Rudrappa2, Santosh Kumar M.1

2024, 44(1), 59-64, 10.51248/.v44i1.4117, May 1, 2024

Introduction and Aim: The biosynthetic method of naturally occurring pigment melanin production has become a predominant technique in recent years owing to its cost-effectiveness, low chemical usage, and reduced purification procedure. This study aimed to investigate the signifi…

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  • Open Access
  • Original Article

Evaluation of in vitro antidiabetic, antioxidant, and antibacterial activities of phytochemicals from Memecylon malabaricum Cogn.

Prathap H.M., Vadlapudi Kumar, Manjunatha T., Ruksana F., Vishala E., Savitharani M.

2024, 44(1), 46-51, 10.51248/.v44i1.4119, May 1, 2024

Introduction and Aim: Plant secondary metabolites have been found to have antidiabetic, antioxidant, and antimicrobial properties. Memecylon malabaricum Cogn., is one of endemic plant species belonging to the melastomataceae family which can be found in western ghats, sacred gro…

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  • Open Access
  • Review Article

Tissue-free non-invasive diagnostic methodology for brain tumour: Present scenario and future direction

 

Anirban Ghosh1, Shubhamitra Chaudhuri2 

2024, 44(1), 39-45, 10.51248/.v44i1.4045, April 24, 2024

Intracranial neoplasia is characterized by their various forms and functions including gliomas which are hard to detect properly, monitor and treat in any therapeutic regime. Present day MRI based techniques act efficiently to detect and acquire the spatial information but fall apart to gather s…

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  • Open Access
  • Review Article

Plant based meat products: A sustainable, promising alternative to conventional red meat


Shashi Bala Singh1,2, Ravishankar Patil1,2, Viraj Kiran Jadhav1 

2024, 44(1), 33-38, 10.51248/.v44i1.4136, April 24, 2024

 

 

The demand of the red meat is continuously increasing leading to biodiversity damage and pollution. To overcome this, plant-based meat offers a promising option due to its organoleptic qualities that resembles closely to those of an animal-based meat product. Th…

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  • Open Access
  • Review Article

Awareness, perception, and utilization of the benefits of recently introduced health schemes among the general population of India: A narrative review

 

 Nitin Joseph1, Sourav Valliyodan2, Nitish Shettigar2, Hrithik Shetty2, Vijayalakshmi Rao2, Saloni Ravishankar Kukian

2024, 44(1), 26-32, 10.51248/.v44i1.4121, April 24, 2024

 

Several health schemes have been introduced by the Government of India in recent years. It becomes essential to know the usefulness of these schemes. This narrative review was done to discuss the awareness, perception, and utilisation of the benefits of recent health schemes. Fo…

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  • Open Access
  • Systematic Review

A narrative review on scientific evidence of mechanisms of naturopathy and yoga interventions for rheumatoid arthritis

 Geetha B. Shetty1, Prashanth Shetty2, Balakrishna Shetty3, Abitone V. R.2 

2024, 44(1), 21-25, 10.51248/.v44i1.4120, April 24, 2024

 Rheumatoid arthritis (RA) is a chronic autoimmune systemic inflammatory disease, which has serious physical, psychological, and social consequences. Many RA patients continue to experience intolerable side effects from their treatments or an inadequate response, which leads to the disease …

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  • Open Access
  • Review Article

Thymoquinone: A novel treatment option for triple negative breast cancer

Vani Mamillapalli1, Vinuthna Rallapalli1, Zyba Mohammed1, Dharani Motukuru 1, SRG Sowgandhika Kosuri3, Padmalatha Kantamaneni

2024, 44(1), 13-20, 10.51248/.v44i1.4155, April 24, 2024

The most common treatment modes of cancer include chemotherapies along with other modes of treatment. But often resistance is developed and gruels towards the discovery of new modes of treatment for cancer. Natural products are used for ages in the treatment. One such component is thymoquinone (…

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  • Open Access
  • Review Article

Unravelling the cardiovascular symphony: Decoding the intricate influence of green tea polyphenols from leaf to heart

 Priya K. S.1, Martin Lucas A.2, Dinesh Sosalagere Manjegowda3 

2024, 44(1), 01-12, 10.51248/.v44i1.4115, April 24, 2024

The extensive exploration of green tea's therapeutic potential in relation to cardiovascular ailments has sparked considerable global interest. The green tea polyphenols notably EGCG, ECG, EGC, EC, and various catechins, exhibit considerable promise as agents with cardioprotective attributes…

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