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Anthracycline Chemistry and Biology I

Biological Occurence and Biosynthesis, Synthesis and Chemistry

  • Book
  • © 2008

Overview

Editors:
  1. Karsten Krohn
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  • This series presents critical reviews of the present position and future trends in modern chemical research
  • Short and concise reports on chemistry, each written by the world renowned experts
  • Still valid and useful after 5 or 10 years
  • More information as well as the electronic version of the whole content available at: springerlink.com
  • Includes supplementary material: sn.pub/extras

Part of the book series: Topics in Current Chemistry (TOPCURRCHEM, volume 282)

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Table of contents (9 chapters)

  1. Front Matter

    Pages I-XIV
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  2. Biological Occurence and Biosynthesis

    1. Front Matter

      Pages 1-2
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    2. Naturally Occurring Anthracyclines

      • Hartmut Laatsch, Serge Fotso
      Pages 3-74

    3. Biosynthetic Anthracycline Variants

      • Jarmo Niemi, Mikko Metsä-Ketelä, Gunter Schneider, Pekka Mäntsälä
      Pages 75-99

    4. Anthracycline Biosynthesis: Genes, Enzymes and Mechanisms

      • Mikko Metsä-Ketelä, Jarmo Niemi, Pekka Mäntsälä, Gunter Schneider
      Pages 101-140

  3. Synthesis and Chemistry

    1. Front Matter

      Pages 141-142
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    2. Synthesis of Enantiomerically Pure Anthracyclinones

      • Osman Achmatowicz, Barbara Szechner
      Pages 143-186

    3. Combinatorial Synthesis of Linearly Condensed Polycyclic Compounds, Including Anthracyclinones, Through Tandem Diels–Alder Additions

      • Pierre Vogel
      Pages 187-214

    4. Fluorinated Anthracyclines

      • Giuseppe Giannini, Domenico Alloatti
      Pages 215-248

    5. Synthesis of the Sugar Moieties

      • Grzegorz Grynkiewicz, Wieslaw Szeja
      Pages 249-284

    6. Nonnatural Glycosyl Anthraquinones as DNA Binding and Photocleaving Agents

      • Kazunobu Toshima
      Pages 285-298

    7. Syntheses of Anthracyclines and Fredericamycin A via Strong Base-Induced Cycloaddition Reaction of Homophthalic Anhydrides

      • Yasuyuki Kita, Hiromichi Fujioka
      Pages 299-319

  4. Back Matter

    Pages 321-324
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Keywords

Reviews

From the reviews:

"This book … covers many different aspects of the origin, chemistry, and biosynthesis of one of the oldest but most important classes of anticancer agents. … In summary, the book is nicely produced, very well edited, and should serve as a valuable source of information … . This book will serve as an inspiration for scientists and students in the areas of chemistry, drug discovery, and biological evaluation. It should be an essential addition to institutional library collections … ." (Waldemar Priebe, Journal of the American Chemical Society, Vol. 131 (23), 2009)

Bibliographic Information

  • Book Title: Anthracycline Chemistry and Biology I

  • Book Subtitle: Biological Occurence and Biosynthesis, Synthesis and Chemistry

  • Editors: Karsten Krohn

  • Series Title: Topics in Current Chemistry

  • DOI: https://doi.org/10.1007/978-3-540-75815-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2008

  • Hardcover ISBN: 978-3-540-75814-3Published: 09 July 2008

  • Softcover ISBN: 978-3-642-09496-5Published: 19 November 2010

  • eBook ISBN: 978-3-540-75815-0Published: 29 October 2009

  • Series ISSN: 0340-1022

  • Series E-ISSN: 1436-5049

  • Edition Number: 1

  • Number of Pages: XIV, 324

  • Number of Illustrations: 135 b/w illustrations

  • Topics: Organic Chemistry, Medicinal Chemistry, Biochemistry, general

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