Overview
- In each volume an overview chapter introduces the newcomer to the topic covered
- Series covers hot topics of frontier research summarized by reputed scientists in the field
- Review series is topic related
- Online version available on SpringerLink: springerlink.com
Part of the book series: Topics in Medicinal Chemistry (TMC, volume 2)
Access this book
Tax calculation will be finalised at checkout
Other ways to access
Table of contents (6 chapters)
-
Front Matter
-
Back Matter
Keywords
About this book
Alzheimer’s disease (AD) is a neurodegenerative disease that robs the minds of our elderly population. Approximately one in every eight adults over the age of 65 and nearly half of those over 85 are afflicted with this disease. The aging population in developed societies will impose an ever increasing socioeconomic threat in the future. Current medicines for AD patients are mainly symptomatic treatments and a huge unmet medical need exists to slow the progression of this disease. A great deal of research has been dedicated to understanding the pathogenesis of AD from which comes many ideas for intervening with its progression. Some of these ideas have been fast-tracked to clinical trials due to the availability of medicines with proven clinical efficacies for other diseases (e.g. atorvastatin, simvastatin, rosiglitazone and clioquinol) while others represent novel chemical entities (e.g. glycogen synthase kinase-3 inhibitors).
This volume will first review existing cholinesterase inhibitors prescribed for AD patients followed by some target mechanisms with ongoing clinical trials. It offers a glimpse of what our future medicine cabinets may look like for AD patients. It also provides an interesting read on why and how current medicines for other indications could potentially be used to treat AD.
Bibliographic Information
Book Title: Alzheimer's Disease
Editors: Lit-Fui Lau, Michael A. Brodney
Series Title: Topics in Medicinal Chemistry
DOI: https://doi.org/10.1007/978-3-540-74229-6
Publisher: Springer Berlin, Heidelberg
eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2008
Hardcover ISBN: 978-3-540-74228-9Published: 22 January 2008
Softcover ISBN: 978-3-642-09354-8Published: 30 November 2010
eBook ISBN: 978-3-540-74229-6Published: 18 December 2007
Series ISSN: 1862-2461
Series E-ISSN: 1862-247X
Edition Number: 1
Number of Pages: XIII, 179
Topics: Medicinal Chemistry, Pharmacology/Toxicology, Organic Chemistry, Molecular Medicine