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Abstract
The molecular and crystal structure of Nα-benzyloxycarbonyl-l-proline amide (Z-l-Pro – NH2) (1) has been determined by X-ray diffraction. The compound possesses the following parameters: orthorhombic, space group P212121 (No. 19), a = 18.113(2) Å, b = 13.809(2) Å, c = 5.010(2) Å, and Z = 4. The crystal structure was solved by direct methods. The least-squares refinement led to R and Rw values of 0.045 and 0.046, respectively, for 1082 reflections with I [unk] 3σ(I). This Pro derivative adopts the collagen-type conformation. The Z-Pro tertiary urethane bond is found in the cis disposition.
Published Online: 2010-08-25
Published in Print: 1992
