Watching the emergence of hematopoietic stem cells

Latest research

1. 1. Ecology

   Polarised Moonlight Guides Nocturnal Bull Ants Home

   Cody A Freas, Ajay Narendra ... Ken Cheng
2. 1. Immunology and Inflammation

   The interferon-rich skin environment regulates Langerhans cell ADAM17 to promote photosensitivity in lupus

   Thomas Morgan Li, Victoria Zyulina ... Theresa T Lu
3. 1. Developmental Biology
   2. Neuroscience

   A unique multi-synaptic mechanism involving acetylcholine and GABA regulates dopamine release in the nucleus accumbens through early adolescence in male rats

   Melody C Iacino, Taylor A Stowe ... Mark J Ferris
4. 1. Neuroscience

   Nitric oxide modulates contrast suppression in a subset of mouse retinal ganglion cells

   Dominic Gonschorek, Matías A. Goldin ... Thomas Euler
5. 1. Stem Cells and Regenerative Medicine

   Dynamic Tracking of Native Polyclonal Hematopoiesis in Adult Mice

   Suying Liu, Sarah E. Adams ... Peter Kurre
6. 1. Neuroscience

   Stochastic characterization of navigation strategies in an automated variant of the Barnes maze

   Ju-Young Lee, Dahee Jung, Sébastien Royer
7. 1. Chromosomes and Gene Expression
   2. Neuroscience

   Molecular basis of neurodegeneration in a mouse model of Polr3-related disease

   Robyn D. Moir, Emilio Merheb ... Ian M. Willis
8. 1. Biochemistry and Chemical Biology
   2. Evolutionary Biology

   Fitness landscape of substrate-adaptive mutations in evolved APC transporters

   Foteini Karapanagioti, Úlfur Á. Atlason ... Sebastian Obermaier
9. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   Rapid, DNA-induced interface swapping by DNA gyrase

   Thomas RM Germe, Natassja G Bush ... Anthony Maxwell

   DNA gyrase, a regulator of bacterial genomes topology, is shown to undergo rearrangements while functioning on DNA in vitro, with important potential consequences for gyrase-targeted antibiotics activity and bacterial evolution.
10. 1. Neuroscience

    Cell-autonomous role of leucine-rich repeat kinase in the protection of dopaminergic neuron survival

    Jongkyun Kang, Guodong Huang ... Jie Shen

    LRRK plays an essential, cell-intrinsic role in the protection of dopaminergic neurons during aging, and new genetic findings suggest that LRRK2 mutations may impair its function, leading to dopaminergic neurodegeneration in PD.