The 2023 MDPI Annual Report has
been released!
 
22 pages, 7448 KiB  
Article
End-to-End Framework for the Automatic Matching of Omnidirectional Street Images and Building Data and the Creation of 3D Building Models
by Yoshiki Ogawa, Ryoto Nakamura, Go Sato, Hiroya Maeda and Yoshihide Sekimoto
Remote Sens. 2024, 16(11), 1858; https://doi.org/10.3390/rs16111858 (registering DOI) - 23 May 2024
Abstract
For accurate urban planning, three-dimensional (3D) building models with a high level of detail (LOD) must be developed. However, most large-scale 3D building models are limited to a low LOD of 1–2, as the creation of higher LOD models requires the modeling of [...] Read more.
For accurate urban planning, three-dimensional (3D) building models with a high level of detail (LOD) must be developed. However, most large-scale 3D building models are limited to a low LOD of 1–2, as the creation of higher LOD models requires the modeling of detailed building elements such as walls, windows, doors, and roof shapes. This process is currently not automated and is performed manually. In this study, an end-to-end framework for the creation of 3D building models was proposed by integrating multi-source data such as omnidirectional images, building footprints, and aerial photographs. These different data sources were matched with the building ID considering their spatial location. The building element information related to the exterior of the building was extracted, and detailed LOD3 3D building models were created. Experiments were conducted using data from Kobe, Japan, yielding a high accuracy for the intermediate processes, such as an 86.9% accuracy in building matching, an 88.3% pixel-based accuracy in the building element extraction, and an 89.7% accuracy in the roof type classification. Eighty-one LOD3 3D building models were created in 8 h, demonstrating that our method can create 3D building models that adequately represent the exterior information of actual buildings. Full article
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16 pages, 8799 KiB  
Article
Extraction of His Bundle Pacing Lead: More Difficult than Coronary Sinus Lead Extraction: An Analysis of 3897 Lead Extraction Procedures Including 27 His and 253 Coronary Sinus Lead Removals
by Paweł Stefańczyk, Wojciech Jacheć, Andrzej Kutarski, Paweł Dąbrowski, Andrzej Głowniak and Dorota Nowosielecka
Biomedicines 2024, 12(6), 1154; https://doi.org/10.3390/biomedicines12061154 (registering DOI) - 23 May 2024
Abstract
Background: Experience with the transvenous extraction of leads used for His bundle pacing (HBP) is limited. Methods: Analysis of 3897 extractions including 27 HBP and 253 LVP (left ventricular pacing) leads. Results: The main reason for HBP lead extraction was lead failure (59.26%). [...] Read more.
Background: Experience with the transvenous extraction of leads used for His bundle pacing (HBP) is limited. Methods: Analysis of 3897 extractions including 27 HBP and 253 LVP (left ventricular pacing) leads. Results: The main reason for HBP lead extraction was lead failure (59.26%). The age of HBP and LVP leads (54.52 vs. 50.20 months) was comparable, whereas procedure difficulties were related to the LVP lead dwell time. The extraction of HBP leads > 40 months old was longer than the removal of younger leads (8.57 vs. 3.87 min), procedure difficulties occurred in 14.29%, and advanced tools were required in 28.57%. There were no major complications. The extraction time of dysfunctional or infected leads was similar in the HBP and LVP groups (log-rank p = 0.868) but shorter when compared to groups with other leads. Survival after the procedure did not differ between HBP and LVP groups but was shorter than in the remaining patients. Conclusions: 1. HBP is used in CRT-D systems for resynchronisation of the failing heart in 33.33%. 2. Extraction of HBP leads is most frequently performed for non-infectious indications (59.26%) and most often because of lead dysfunction (33.33%). 3. The extraction of “old” (>40 months) HBP leads is longer (8.57 vs. 3.87 min) and more difficult than the removal of “young” leads due to unexpected procedure difficulties (14.29%) and the use of second line/advanced tools (28.57%), but it does not entail the risk of major complications and procedure-related death and is comparable to those encountered in the extraction of LVP leads of a similar age. 4. Survival after lead extraction was comparable between HBP and LVP groups but shorter compared to patients who underwent the removal of other leads Full article
(This article belongs to the Section Molecular and Translational Medicine)
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12 pages, 1991 KiB  
Article
Soil and Urine Mercury Levels in Secocha: A Case Study of Artisanal and Small-Scale Gold Mining in Peru
by Rolando Quispe Aquino, Fredy Fortunato García Zúñiga and Aaron Malone
Mining 2024, 4(2), 389-400; https://doi.org/10.3390/mining4020022 (registering DOI) - 23 May 2024
Abstract
In recent decades, artisanal and small-scale gold mining (ASGM) has spurred population and economic growth in the small rural communities in which it is located, along with causing contamination of the soil, air, and water with grave effects on human health due to [...] Read more.
In recent decades, artisanal and small-scale gold mining (ASGM) has spurred population and economic growth in the small rural communities in which it is located, along with causing contamination of the soil, air, and water with grave effects on human health due to the uncontrolled use of mercury for gold processing activities. This study analyzes the levels of mercury in Secocha, an ASGM community in Arequipa, Peru. A total of 44 soil samples were taken from two ASGM commercial-extractive zones (n = 18) and non-processing urban zones (n = 26). Soil mercury analysis with atomic absorption spectrometry revealed average mercury levels of 86.11 mg/kg in commercial-extractive zone I, where ore processing has occurred for about 17 years, and mercury levels of 43.81 mg/kg in commercial-extractive zone II, where processing has occurred for about 7 years. In the urban zone, the average mercury level was 9.53 mg/kg. The average mercury concentrations for each zone exceed the relevant environmental quality standards established by the Peruvian Ministry of the Environment. In addition, urine samples were obtained from 15 miners and 15 people from the general urban population (non-miners). The average mercury level in the urine of miners was 7.04 µg/L, and in the urine of non-miners it was 0.49 µg/L. In both cases, the mercury urine level did not exceed the limits established by WHO and the Peruvian Ministry of Health, though miners’ elevated levels do raise concerns. Full article
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10 pages, 391 KiB  
Systematic Review
The Use of Barbed Sutures in Total Hip Arthroplasty: A Systematic Review on Clinical–Surgical Outcomes, Costs, and Complications
by Antonio Russo, Michele Centola, Alberto Nicodemo and Alessandro Massè
Healthcare 2024, 12(11), 1063; https://doi.org/10.3390/healthcare12111063 (registering DOI) - 23 May 2024
Abstract
Purpose: Total hip arthroplasty is among the most successful procedures in orthopaedic surgery. As the total number of total hip arthroplasties is constantly rising and it is expected to further increase, efforts oriented to optimise surgical pathways are investigated, aiming to reduce complications [...] Read more.
Purpose: Total hip arthroplasty is among the most successful procedures in orthopaedic surgery. As the total number of total hip arthroplasties is constantly rising and it is expected to further increase, efforts oriented to optimise surgical pathways are investigated, aiming to reduce complications and diminish costs. The wound suturing phase is one of the steps that may be addressed. Barbed sutures have proved to reduce surgical times and enhance suture stability, then reducing wound-related complications in many surgical fields. The evidence on the use of this technology in total hip arthroplasty is still sparse, and its effect on patient outcomes and costs must still be clarified. Methods: A systematic search of studies published from 1 January 2000 to 1 March 2023 was performed. Two authors independently reviewed the literature available in eight electronic databases to identify papers eligible for inclusion. Results: A total of nine studies investigating 6959 procedures on 6959 patients were included in the final analysis. Five studies were randomised controlled trials, and the overall quality of studies ranged from moderate to high. The mean age of patients ranged from 43.8 to 70 years. BMI ranged from 25 to 31.9 kg/m2. The mean follow-up of studies ranged from 3 to 6 months. Conclusions: Evidence included in the systematic review suggested that the use of barbed sutures is associated with lower suturing times, complication rates, and overall costs when compared to the use of traditional suturing techniques. Level of evidence: II, systematic review of level I and II studies. Full article
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29 pages, 571 KiB  
Article
Secrecy Analysis of a Mu-MIMO LIS-Aided Communication Systems under Nakagami-m Fading Channels
by Ricardo Coelho Ferreira, Gustavo Fraidenraich, Felipe A. P. de Figueiredo and Eduardo Rodrigues de Lima
Sensors 2024, 24(11), 3332; https://doi.org/10.3390/s24113332 (registering DOI) - 23 May 2024
Abstract
This study evaluates the performance of large intelligent surface (LIS) technology in the context of a multi-user MIMO mobile communication system (Mu-MIMO) proposed for the sixth generation (6G). LIS employs digitally controlled reflectors to enhance Signal-to-Interference plus Noise Ratio (SINR) and establish line [...] Read more.
This study evaluates the performance of large intelligent surface (LIS) technology in the context of a multi-user MIMO mobile communication system (Mu-MIMO) proposed for the sixth generation (6G). LIS employs digitally controlled reflectors to enhance Signal-to-Interference plus Noise Ratio (SINR) and establish line of sight (LoS) connectivity in non-LoS environments, improving transmission security. Analytical expressions are derived to assess LIS performance metrics, including distribution parameters, bit error probability, and secrecy outage probability, considering the presence of eavesdroppers and environmental fading. The study highlights the potential of LIS technology to enhance the confidentiality and reliability of digital communication systems in next-generation networks. Full article
(This article belongs to the Section Communications)
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15 pages, 8669 KiB  
Article
Investigating Genetic Diversity and Population Structure in Rice Breeding from Association Mapping of 116 Accessions Using 64 Polymorphic SSR Markers
by Alok Kumar Singh, Devendra Kumar, Donato Gemmati, Ranjith Kumar Ellur, Ashutosh Singh, Veronica Tisato, Devendra Kumar Dwivedi, Sanjay Kumar Singh, Kishor Kumar, Nawaz Ahmad Khan and Ajay Vikram Singh
Crops 2024, 4(2), 180-194; https://doi.org/10.3390/crops4020014 (registering DOI) - 23 May 2024
Abstract
Genetic variability in rice breeding programs plays a very crucial role. It provides an outstanding pool of superior alleles governing better agronomic and quality characters through association mapping. For a greater understanding of population structure, the genetic relationship among different rice lines is [...] Read more.
Genetic variability in rice breeding programs plays a very crucial role. It provides an outstanding pool of superior alleles governing better agronomic and quality characters through association mapping. For a greater understanding of population structure, the genetic relationship among different rice lines is indispensable prior to the setting of a correlation among dynamic alleles and traits. In the present investigation, the genetic diversity and population structure of 116 rice accessions were studied to understand genetic relatedness and diversity among them using 64 polymorphic SSR markers. A genotyping assessment based on SSR markers revealed a total of 225 alleles, with an average PIC value of 0.755. The germplasm lines were classified into three distinct subgroups through population structure analysis, utilizing both model- and distance-based approaches. AMOVA analysis showed that 11% of the total variation could be attributed to differences between groups, while the remaining 89% was likely due to differences within groups. This study suggested that population structure and genetic relatedness should be considered to establish marker–trait associations for association mapping when working with the core collection of germplasm lines. Full article
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18 pages, 4681 KiB  
Article
Genetic Diversity and Relationships among Indian Jujube (Ziziphus mauritiana Lamk.) Cultivars Using Morphometric Characteristics, matK Barcoding, and ISSR Markers
by Mahmoud Abdel-Sattar, Rashid S. Al-Obeed, Hail Z. Rihan and Ghada E. El-Badan
Diversity 2024, 16(6), 313; https://doi.org/10.3390/d16060313 (registering DOI) - 23 May 2024
Abstract
Indian jujube displays genetic diversity and does not prominently display minute morphometric variations, and this makes correct identification a difficult and long-term task. However, little work has been conducted to bring jujube cultivars into domestication. So, the present study aimed to evaluate eleven [...] Read more.
Indian jujube displays genetic diversity and does not prominently display minute morphometric variations, and this makes correct identification a difficult and long-term task. However, little work has been conducted to bring jujube cultivars into domestication. So, the present study aimed to evaluate eleven cultivars of Indian jujube in terms of the fruit’s morphometric characteristics, as well as molecular marker studies by plastidial megakaryocyte-associated tyrosine kinase (matK) barcoding and inter-simple sequence repeats (ISSR) markers for species differentiation, identification, and relationships among Indian jujube cultivars. The results of the morphometric characteristics showed that the mean geometric diameter, surface area, sphericity, sphericity ratio, shape index, fruit length, fruit diameter, fruit weight, and seed weight varied among cultivars. The results also showed that the color values of L*, a*, and b* for fruits differed in different cultivars. In addition, the results showed a discrepancy in the genetic diversity parameters related to the matK barcoding, ISSR markers, and relationships among Indian jujube cultivars. Substantially, hierarchical clustering by heatmap revealed that ‘Zytoni’ and ‘Um-Sulaem’ with spines seem to be mono-clades distinct from other cultivars, which related to variations in the expression levels of genes. Therefore, they should be relied upon together to distinguish and identify cultivars in order to maximize the effectiveness of local germplasm conservation and exploitation. Full article
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19 pages, 1752 KiB  
Article
Integration of Horse Manure Vermicompost Doses and Arbuscular Mycorrhizal Fungi to Improve Fruit Quality, and Soil Fertility in Tomato Field Facing Drought Stress
by Soufiane Lahbouki, Abeer Hashem, Ajay Kumar, Elsayed Fathi Abd_Allah and Abdelilah Meddich
Plants 2024, 13(11), 1449; https://doi.org/10.3390/plants13111449 (registering DOI) - 23 May 2024
Abstract
Climate change poses major challenges for agriculture in arid and semi-arid regions, with drought conditions severely affecting water-intensive crops such as tomatoes. This study evaluates the efficacy of organic amendments, derived from horse manure, and arbuscular mycorrhizal fungi (AMF) on enhancing tomato ( [...] Read more.
Climate change poses major challenges for agriculture in arid and semi-arid regions, with drought conditions severely affecting water-intensive crops such as tomatoes. This study evaluates the efficacy of organic amendments, derived from horse manure, and arbuscular mycorrhizal fungi (AMF) on enhancing tomato (Solanum lycopersicum L.) fruit quality and soil health under semi-arid field conditions. The experimental design included two irrigation regimes (well-watered and drought stress) and two levels of vermicompost application (C1 5 t ha−1 and C2 10 t ha−1), applied individually or in combination with AMF. The results indicate that drought stress reduced tomato fruit growth and yield, while osmoprotectant accumulation, antioxidant enzyme activity, and bioactive compound levels increased, and the 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity of tomato fruit also increased. Notably, the biostimulants application, especially (C1+AMF), counteracted the adverse effects of drought, compared to the control, by significantly enhancing fruit yields (60%), as well as increasing ascorbic acid levels (59%) and free amino acids content (90%). These treatments also improved the activity of bioactive compounds and nutrient uptake in the fruit. Furthermore, biostimulant application positively affected the physicochemical properties of soil. The results obtained confirm that the application of biostimulants can be suitable for improving crop sustainability and adaptability under conditions of water stress in semi-arid field regions. Full article
(This article belongs to the Special Issue Soil-Beneficial Microorganisms and Plant Growth)
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14 pages, 3575 KiB  
Article
Shape Dependence of Photoresponsive Molecular Crystals Composed of Naphthyl Acrylic Acid Stimulated by Solid-State [2 + 2] Photocycloaddition
by Tian-Yuan Li, Yu-Ze Du, Tian-Yi Xu, Tian-Le Zhang and Fei Tong
Crystals 2024, 14(6), 492; https://doi.org/10.3390/cryst14060492 (registering DOI) - 23 May 2024
Abstract
Photomechanical molecular crystals, actuated by solid-state photochemical reactions, manifest a spectrum of mechanical motions upon light exposure, underscoring their prospective integration into the next generation of intelligent materials and devices. Utilizing the solid-state photodimerization of naphthyl acrylic acid as a paradigm, this study [...] Read more.
Photomechanical molecular crystals, actuated by solid-state photochemical reactions, manifest a spectrum of mechanical motions upon light exposure, underscoring their prospective integration into the next generation of intelligent materials and devices. Utilizing the solid-state photodimerization of naphthyl acrylic acid as a paradigm, this study delved into the interplay between crystal morphology and reaction dynamics on the photomechanical responses of molecular crystals. Distinct crystal forms—bulk, microrods, and microplates—were cultivated through tailored crystallization conditions. While bulk crystals of naphthyl acrylic acid (NA) underwent shattering and splintering upon UV light exposure, the microplate counterparts displayed unique cracking patterns with fissures yet retained their overall structural integrity. In contrast, NA microrods underwent pronounced bending under identical irradiation conditions. These phenomena are attributed to the efficient lattice reconfiguration stemming from the [2 + 2] cycloaddition photochemical reaction within the crystals. An intermediate fluorescence enhancement was observed across all crystal types upon light exposure. Collectively, our results underscore the pivotal role of crystal shape in dictating photomechanical behavior, thereby heralding novel strategies for developing advanced photomechanical materials. Full article
(This article belongs to the Section Organic Crystalline Materials)
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18 pages, 5415 KiB  
Article
Distinct Gut Microbiota and Arachidonic Acid Metabolism in Obesity-Prone and Obesity-Resistant Mice with a High-Fat Diet
by Huixia Zhang, Shiqi Chen, Liu Yang, Shuai Zhang, Linqian Qin and Haiyang Jiang
Nutrients 2024, 16(11), 1579; https://doi.org/10.3390/nu16111579 (registering DOI) - 23 May 2024
Abstract
An imbalance of energy intake and expenditure is commonly considered as the fundamental cause of obesity. However, individual variations in susceptibility to obesity do indeed exist in both humans and animals, even among those with the same living environments and dietary intakes. To [...] Read more.
An imbalance of energy intake and expenditure is commonly considered as the fundamental cause of obesity. However, individual variations in susceptibility to obesity do indeed exist in both humans and animals, even among those with the same living environments and dietary intakes. To further explore the potential influencing factors of these individual variations, male C57BL/6J mice were used for the development of obesity-prone and obesity-resistant mice models and were fed high-fat diets for 16 weeks. Compared to the obesity-prone mice, the obesity-resistant group showed a lower body weight, liver weight, adipose accumulation and pro-inflammatory cytokine levels. 16S rRNA sequencing, which was conducted for fecal microbiota analysis, found that the fecal microbiome’s structural composition and biodiversity had changed in the two groups. The genera Allobaculumbiota, SMB53, Desulfovibrio and Clostridium increased in the obesity-prone mice, and the genera Streptococcus, Odoribacter and Leuconostoc were enriched in the obesity-resistant mice. Using widely targeted metabolomics analysis, 166 differential metabolites were found, especially those products involved in arachidonic acid (AA) metabolism, which were significantly reduced in the obesity-resistant mice. Moreover, KEGG pathway analysis exhibited that AA metabolism was the most enriched pathway. Significantly altered bacteria and obesity-related parameters, as well as AA metabolites, exhibited strong correlations. Overall, the phenotypes of the obesity-prone and obesity-resistant mice were linked to gut microbiota and AA metabolism, providing new insight for developing an in-depth understanding of the driving force of obesity resistance and a scientific reference for the targeted prevention and treatment of obesity. Full article
(This article belongs to the Section Prebiotics and Probiotics)
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27 pages, 3442 KiB  
Article
A Low-Cost Ecofriendly Oxidation Process to Manufacture High-Performance Polymeric Biosurfactants Derived from Municipal Biowaste
by Elio Padoan, Francesco Contillo, Matteo Marafante, Enzo Montoneri, Matteo Francavilla, Silvia Berto and Andrea Baglieri
Polymers 2024, 16(11), 1479; https://doi.org/10.3390/polym16111479 (registering DOI) - 23 May 2024
Abstract
Biosurfactants account for about 12% of the global value of the surfactant market, which is currently dominated by synthetic surfactants obtained from fossil sources. Yet, the production of biosurfactants from renewable feedstock is bound to increase, driven by the increasing pressure from both [...] Read more.
Biosurfactants account for about 12% of the global value of the surfactant market, which is currently dominated by synthetic surfactants obtained from fossil sources. Yet, the production of biosurfactants from renewable feedstock is bound to increase, driven by the increasing pressure from both society and governments for chemistry-based industries to become more ecofriendly and economically sustainable. A photo-chemical oxidation process is reported here, yielding new biosurfactants from urban biowaste in water that perform as a solvent and terminal oxidant reagent at room temperature without the addition of conventional oxidants and catalysts. Products with 200–500 kDa molecular weight are obtained. They lower the surface tension of water down to 34 mN/m at 0.5–2 g/L concentration. The estimated cost is rather low (0.1–1.5 EUR/kg), which is competitive with the cost of synthetic surfactants but much lower than the cost of the best-performing bacterial surfactants. For the implementation of the photo-chemical oxidation process at the industrial level, the results suggest that the new biosurfactants obtained in the present work may not reach the performance level of the best-performing bacterial surfactants capable of lowering the surface tension of water down to 28 mN/m. Yet, the biosurfactants produced by the photo-chemical process have a greater chance of being marketed on large scales. Full article
(This article belongs to the Special Issue Biorefinery: From Wastes to Biopolymers)
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27 pages, 2040 KiB  
Article
Machine Learning Decision System on the Empirical Analysis of the Actual Usage of Interactive Entertainment: A Perspective of Sustainable Innovative Technology
by Rex Revian A. Guste and Ardvin Kester S. Ong
Computers 2024, 13(6), 128; https://doi.org/10.3390/computers13060128 (registering DOI) - 23 May 2024
Abstract
This study focused on the impact of Netflix’s interactive entertainment on Filipino consumers, seamlessly combining vantage points from consumer behavior and employing data analytics. This underlines the revolutionary aspect of interactive entertainment in the quickly expanding digital media ecosystem, particularly as Netflix pioneers [...] Read more.
This study focused on the impact of Netflix’s interactive entertainment on Filipino consumers, seamlessly combining vantage points from consumer behavior and employing data analytics. This underlines the revolutionary aspect of interactive entertainment in the quickly expanding digital media ecosystem, particularly as Netflix pioneers fresh content distribution techniques. The main objective of this study was to find the factors impacting the real usage of Netflix’s interactive entertainment among Filipino viewers, filling a critical gap in the existing literature. The major goal of using advanced data analytics techniques in this study was to understand the subtle dynamics affecting customer behavior in this setting. Specifically, the random forest classifier with hard and soft classifiers was assessed. The random forest compared to LightGBM was also employed, alongside the different algorithms of the artificial neural network. Purposive sampling was used to obtain responses from 258 people who had experienced Netflix’s interactive entertainment, resulting in a comprehensive dataset. The findings emphasized the importance of hedonic motivation, underlining the requirement for highly engaging and rewarding interactive material. Customer service and device compatibility, for example, have a significant impact on user uptake. Furthermore, behavioral intention and habit emerged as key drivers, revealing interactive entertainment’s long-term influence on user engagement. Practically, the research recommends strategic platform suggestions that emphasize continuous innovation, user-friendly interfaces, and user-centric methods. This study was able to fill in the gap in the literature on interactive entertainment, which contributes to a better understanding of consumer consumption and lays the groundwork for future research in the dynamic field of digital media. Moreover, this study offers essential insights into the intricate interaction of consumer preferences, technology breakthroughs, and societal influences in the ever-expanding environment of digital entertainment. Lastly, the comparative approach to the use of machine learning algorithms provides insights for future works to adopt and employ among human factors and consumer behavior-related studies. Full article
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14 pages, 8343 KiB  
Article
Silver Nanowire-Based Flexible Strain Sensor for Human Motion Detection
by Abduweli Mijit, Shuo Li, Qiang Wang, Mingzhou Li and Yanlong Tai
Sensors 2024, 24(11), 3329; https://doi.org/10.3390/s24113329 (registering DOI) - 23 May 2024
Abstract
Accurately capturing human movements is a crucial element of health status monitoring and a necessary precondition for realizing future virtual reality/augmented reality applications. Flexible motion sensors with exceptional sensitivity are capable of detecting physical activities by converting them into resistance fluctuations. Silver nanowires [...] Read more.
Accurately capturing human movements is a crucial element of health status monitoring and a necessary precondition for realizing future virtual reality/augmented reality applications. Flexible motion sensors with exceptional sensitivity are capable of detecting physical activities by converting them into resistance fluctuations. Silver nanowires (AgNWs) have become a preferred choice for the development of various types of sensors due to their outstanding electrical conductivity, transparency, and flexibility within polymer composites. Herein, we present the design and fabrication of a flexible strain sensor based on silver nanowires. Suitable substrate materials were selected, and the sensor’s sensitivity and fatigue properties were characterized and tested, with the sensor maintaining reliability after 5000 deformation cycles. Different sensors were prepared by controlling the concentration of silver nanowires to achieve the collection of motion signals from various parts of the human body. Additionally, we explored potential applications of these sensors in fields such as health monitoring and virtual reality. In summary, this work integrated the acquisition of different human motion signals, demonstrating great potential for future multifunctional wearable electronic devices. Full article
(This article belongs to the Section Chemical Sensors)
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30 pages, 1261 KiB  
Review
Merits and Demerits of Machine Learning of Ferroelectric, Flexoelectric, and Electrolytic Properties of Ceramic Materials
by Kyuichi Yasui
Materials 2024, 17(11), 2512; https://doi.org/10.3390/ma17112512 (registering DOI) - 23 May 2024
Abstract
In the present review, the merits and demerits of machine learning (ML) in materials science are discussed, compared with first principles calculations (PDE (partial differential equations) model) and physical or phenomenological ODE (ordinary differential equations) model calculations. ML is basically a fitting procedure [...] Read more.
In the present review, the merits and demerits of machine learning (ML) in materials science are discussed, compared with first principles calculations (PDE (partial differential equations) model) and physical or phenomenological ODE (ordinary differential equations) model calculations. ML is basically a fitting procedure of pre-existing (experimental) data as a function of various factors called descriptors. If excellent descriptors can be selected and the training data contain negligible error, the predictive power of a ML model is relatively high. However, it is currently very difficult for a ML model to predict experimental results beyond the parameter space of the training experimental data. For example, it is pointed out that all-dislocation-ceramics, which could be a new type of solid electrolyte filled with appropriate dislocations for high ionic conductivity without dendrite formation, could not be predicted by ML. The merits and demerits of first principles calculations and physical or phenomenological ODE model calculations are also discussed with some examples of the flexoelectric effect, dielectric constant, and ionic conductivity in solid electrolytes. Full article
19 pages, 3934 KiB  
Article
The ArgR-Regulated ADI Pathway Facilitates the Survival of Vibrio fluvialis under Acidic Conditions
by Qian Cheng, Yu Han, Yue Xiao, Zhe Li, Aiping Qin, Saisen Ji, Biao Kan and Weili Liang
Int. J. Mol. Sci. 2024, 25(11), 5679; https://doi.org/10.3390/ijms25115679 (registering DOI) - 23 May 2024
Abstract
Vibrio fluvialis is an emerging foodborne pathogenic bacterium that can cause severe cholera-like diarrhea and various extraintestinal infections, posing challenges to public health and food safety worldwide. The arginine deiminase (ADI) pathway plays an important role in bacterial environmental adaptation and pathogenicity. However, [...] Read more.
Vibrio fluvialis is an emerging foodborne pathogenic bacterium that can cause severe cholera-like diarrhea and various extraintestinal infections, posing challenges to public health and food safety worldwide. The arginine deiminase (ADI) pathway plays an important role in bacterial environmental adaptation and pathogenicity. However, the biological functions and regulatory mechanisms of the pathway in V. fluvialis remain unclear. In this study, we demonstrate that L-arginine upregulates the expression of the ADI gene cluster and promotes the growth of V. fluvialis. The ADI gene cluster, which we proved to be comprised of two operons, arcD and arcACB, significantly enhances the survival of V. fluvialis in acidic environments both in vitro (in culture medium and in macrophage) and in vivo (in mice). The mRNA level and reporter gene fusion analyses revealed that ArgR, a transcriptional factor, is necessary for the activation of both arcD and arcACB transcriptions. Bioinformatic analysis predicted the existence of multiple potential ArgR binding sites at the arcD and arcACB promoter regions that were further confirmed by electrophoretic mobility shift assay, DNase I footprinting, or point mutation analyses. Together, our study provides insights into the important role of the ArgR-ADI pathway in the survival of V. fluvialis under acidic conditions and the detailed molecular mechanism. These findings will deepen our understanding of how environmental changes and gene expression interact to facilitate bacterial adaptations and virulence. Full article
(This article belongs to the Special Issue Current Insights into Nucleic Acids)
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10 pages, 734 KiB  
Article
Seasonal Grazing Does Not Significantly Alter the Particle Structure and Pore Characteristics of Grassland Soil
by Juejie Yang, Ruiqi Zhang, Rong Cao, Shikui Dong, Taogetao Baoyin and Tianqi Zhao
Land 2024, 13(6), 730; https://doi.org/10.3390/land13060730 (registering DOI) - 23 May 2024
Abstract
Seasonal grazing is a recognized and sustainable approach to livestock management, but there is still a lack of comprehensive research on its impact on soil structure. This study utilizes advanced scanning electron microscopy technology to quantitatively evaluate the long-term effects of seasonal grazing [...] Read more.
Seasonal grazing is a recognized and sustainable approach to livestock management, but there is still a lack of comprehensive research on its impact on soil structure. This study utilizes advanced scanning electron microscopy technology to quantitatively evaluate the long-term effects of seasonal grazing on grassland soil structure, focusing on soil pore distribution characteristics and particle size. The investigation offers a detailed visual representation of the arrangement of soil particles at a micro-level. In both grazed and ungrazed plots (NG), soil particles ranging from 0.005 to 0.05 mm and 0.075 to 0.25 mm in size were predominant, constituting 20% and 60%, respectively. In plots subjected to seasonal grazing (grazing in June and August, G68, and grazing in July and September, G79), micro-particles (0.002–0.005 mm) and particles sized 0.05–0.075 mm were significantly lower compared to NG. Scanning electron microscope (SEM) images demonstrate structural differences, with NG displaying a higher proportion of small to medium-sized particles, more small pores, and fewer large pores. Analysis of pore size and morphology reveals the prevalence of large pores in both grazed and ungrazed plots. Continuous grazing plots exhibit significantly higher proportions of large pores compared to NG, while seasonal grazing plots show no significant differences. Correlation analyses indicate associations between soil physicochemical properties, particle size, and pore structure. Total soil nitrogen (TN), total soil carbon (TC), and soil moisture positively correlate with 0.005–0.05 mm particle proportions, while EC is negatively correlated with 0.05–0.075 mm particles. This study enhances our understanding of the effects of grazing practices on soil structure and provides scientific evidence for sustainable land management. Full article
19 pages, 4027 KiB  
Article
A Deep Learning Model for Detecting Diabetic Retinopathy Stages with Discrete Wavelet Transform
by A. M. Mutawa, Khalid Al-Sabti, Seemant Raizada and Sai Sruthi
Appl. Sci. 2024, 14(11), 4428; https://doi.org/10.3390/app14114428 (registering DOI) - 23 May 2024
Abstract
Diabetic retinopathy (DR) is the primary factor leading to vision impairment and blindness in diabetics. Uncontrolled diabetes can damage the retinal blood vessels. Initial detection and prompt medical intervention are vital in preventing progressive vision impairment. Today’s growing medical field presents a more [...] Read more.
Diabetic retinopathy (DR) is the primary factor leading to vision impairment and blindness in diabetics. Uncontrolled diabetes can damage the retinal blood vessels. Initial detection and prompt medical intervention are vital in preventing progressive vision impairment. Today’s growing medical field presents a more significant workload and diagnostic demands on medical professionals. In the proposed study, a convolutional neural network (CNN) is employed to detect the stages of DR. This research is crucial for studying DR because of its innovative methodology incorporating two different public datasets. This strategy enhances the model’s capacity to generalize unseen DR images, as each dataset encompasses unique demographics and clinical circumstances. The network can learn and capture complicated hierarchical image features with asymmetric weights. Each image is preprocessed using contrast-limited adaptive histogram equalization and the discrete wavelet transform. The model is trained and validated using the combined datasets of Dataset for Diabetic Retinopathy and the Asia-Pacific Tele-Ophthalmology Society. The CNN model is tuned in with different learning rates and optimizers. An accuracy of 72% and an area under curve score of 0.90 was achieved by the CNN model with the Adam optimizer. The recommended study results may reduce diabetes-related vision impairment by early identification of DR severity. Full article
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16 pages, 3590 KiB  
Article
Mitigating Trunk Compensatory Movements in Post-Stroke Survivors through Visual Feedback during Robotic-Assisted Arm Reaching Exercises
by Seong-Hoon Lee and Won-Kyung Song
Sensors 2024, 24(11), 3331; https://doi.org/10.3390/s24113331 (registering DOI) - 23 May 2024
Abstract
Trunk compensatory movements frequently manifest during robotic-assisted arm reaching exercises for upper limb rehabilitation following a stroke, potentially impeding functional recovery. These aberrant movements are prevalent among stroke survivors and can hinder their progress in rehabilitation, making it crucial to address this issue. [...] Read more.
Trunk compensatory movements frequently manifest during robotic-assisted arm reaching exercises for upper limb rehabilitation following a stroke, potentially impeding functional recovery. These aberrant movements are prevalent among stroke survivors and can hinder their progress in rehabilitation, making it crucial to address this issue. This study evaluated the efficacy of visual feedback, facilitated by an RGB-D camera, in reducing trunk compensation. In total, 17 able-bodied individuals and 18 stroke survivors performed reaching tasks under unrestricted trunk conditions and visual feedback conditions. In the visual feedback modalities, the target position was synchronized with trunk movement at ratios where the target moved at the same speed, double, and triple the trunk’s motion speed, providing real-time feedback to the participants. Notably, trunk compensatory movements were significantly diminished when the target moved at the same speed and double the trunk’s motion speed. Furthermore, these conditions exhibited an increase in the task completion time and perceived exertion among stroke survivors. This outcome suggests that visual feedback effectively heightened the task difficulty, thereby discouraging unnecessary trunk motion. The findings underscore the pivotal role of customized visual feedback in correcting aberrant upper limb movements among stroke survivors, potentially contributing to the advancement of robotic-assisted rehabilitation strategies. These insights advocate for the integration of visual feedback into rehabilitation exercises, highlighting its potential to foster more effective recovery pathways for post-stroke individuals by minimizing undesired compensatory motions. Full article
(This article belongs to the Special Issue Intelligent Autonomous System)
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22 pages, 2019 KiB  
Review
Ball Milling Innovations Advance Mg-Based Hydrogen Storage Materials Towards Practical Applications
by Yaohui Xu, Yuting Li, Quanhui Hou, Yechen Hao and Zhao Ding
Materials 2024, 17(11), 2510; https://doi.org/10.3390/ma17112510 (registering DOI) - 23 May 2024
Abstract
Mg-based materials have been widely studied as potential hydrogen storage media due to their high theoretical hydrogen capacity, low cost, and abundant reserves. However, the sluggish hydrogen absorption/desorption kinetics and high thermodynamic stability of Mg-based hydrides have hindered their practical application. Ball milling [...] Read more.
Mg-based materials have been widely studied as potential hydrogen storage media due to their high theoretical hydrogen capacity, low cost, and abundant reserves. However, the sluggish hydrogen absorption/desorption kinetics and high thermodynamic stability of Mg-based hydrides have hindered their practical application. Ball milling has emerged as a versatile and effective technique to synthesize and modify nanostructured Mg-based hydrides with enhanced hydrogen storage properties. This review provides a comprehensive summary of the state-of-the-art progress in the ball milling of Mg-based hydrogen storage materials. The synthesis mechanisms, microstructural evolution, and hydrogen storage properties of nanocrystalline and amorphous Mg-based hydrides prepared via ball milling are systematically reviewed. The effects of various catalytic additives, including transition metals, metal oxides, carbon materials, and metal halides, on the kinetics and thermodynamics of Mg-based hydrides are discussed in detail. Furthermore, the strategies for synthesizing nanocomposite Mg-based hydrides via ball milling with other hydrides, MOFs, and carbon scaffolds are highlighted, with an emphasis on the importance of nanoconfinement and interfacial effects. Finally, the challenges and future perspectives of ball-milled Mg-based hydrides for practical on-board hydrogen storage applications are outlined. This review aims to provide valuable insights and guidance for the development of advanced Mg-based hydrogen storage materials with superior performance. Full article
(This article belongs to the Section Materials Chemistry)
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16 pages, 587 KiB  
Review
Can Daily Dietary Choices Have a Cardioprotective Effect? Food Compounds in the Prevention and Treatment of Cardiometabolic Diseases
by Elżbieta Szczepańska, Barbara Janota, Marika Wlazło and Magdalena Gacal
Metabolites 2024, 14(6), 296; https://doi.org/10.3390/metabo14060296 (registering DOI) - 23 May 2024
Abstract
Cardiovascular diseases accompanying metabolic syndrome comprise one of the leading causes of death worldwide. The medical community undertakes attempts to improve treatment options and minimize cardiovascular diseases’ numerous consequences and exacerbations. In parallel with pharmacotherapies provided by physicians, nutritionists are developing strategies for [...] Read more.
Cardiovascular diseases accompanying metabolic syndrome comprise one of the leading causes of death worldwide. The medical community undertakes attempts to improve treatment options and minimize cardiovascular diseases’ numerous consequences and exacerbations. In parallel with pharmacotherapies provided by physicians, nutritionists are developing strategies for diet therapy and prevention based on lifestyle changes, with high success rates. Consumption of specified food compounds included in various products with proven protective properties can be helpful in this regard. Due to the wide possibilities of diet in metabolic health promotion, it seems necessary to systematize information about the metabolically protective and cardioprotective properties of fiber, probiotic bacteria, plant sterols, folic acid, vitamins B12, C, and E, PUFAs, lycopene, polyphenols, arginine, CoQ10, and allicin. The aim of this review was to present the food compounds with potential use in cardiometabolic prevention and diet therapy based on the latest available literature. Full article
(This article belongs to the Special Issue Impact of Food and Bioactive Compounds on Metabolic Diseases)
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16 pages, 3066 KiB  
Article
Analysis of Traffic Injury Crash Proportions Using Geographically Weighted Beta Regression
by Alan Ricardo da Silva and Roberto de Souza Marques Buffone
Infrastructures 2024, 9(6), 89; https://doi.org/10.3390/infrastructures9060089 (registering DOI) - 23 May 2024
Abstract
The classical linear regression model allows for a continuous quantitative variable to be modeled simply from other variables. However, this model assumes independence between observations, which, if ignored, can lead to methodological issues. Additionally, not all data follow a normal distribution, prompting the [...] Read more.
The classical linear regression model allows for a continuous quantitative variable to be modeled simply from other variables. However, this model assumes independence between observations, which, if ignored, can lead to methodological issues. Additionally, not all data follow a normal distribution, prompting the need for alternative modeling methods. In this context, geographically weighted beta regression (GWBR) incorporates spatial dependence into the modeling process and analyzes rates or proportions using the beta distribution. In this study, GWBR was applied to the traffic injury (fatal and non-fatal) crash proportions in Fortaleza, Ceará, Brazil, from 2009 to 2011. The results demonstrated that the local approach using the beta distribution is a viable model for explaining the traffic injury crash proportions, due to its flexibility in handling both symmetric and skewed distributions. Therefore, when analyzing rates or proportions, the use of the GWBR model is recommended. Full article
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12 pages, 2951 KiB  
Article
Electrochemical Study and Mechanical Properties of Ti-Zr Alloy for Biomedical Applications
by Iosif Hulka, Ion-Dragoș Uțu, Santiago Brito-Garcia, Amparo Verdu-Vazquez and Julia C. Mirza-Rosca
Crystals 2024, 14(6), 493; https://doi.org/10.3390/cryst14060493 (registering DOI) - 23 May 2024
Abstract
In response to concerns of potential cytotoxicity and adverse tissue reactions caused by vanadium and aluminum in the currently used biomaterial Ti-6Al-4V, the Ti–20Zr alloy was evaluated in this study because it has been suggested as a candidate for human body implant material. [...] Read more.
In response to concerns of potential cytotoxicity and adverse tissue reactions caused by vanadium and aluminum in the currently used biomaterial Ti-6Al-4V, the Ti–20Zr alloy was evaluated in this study because it has been suggested as a candidate for human body implant material. The Ti-20Zr alloy was obtained by vacuum-melting, followed by heat treatment at 1000 °C for 1 h, and then air-cooled. Optical and scanning electron microscopy revealed that the sample had an α and β lamellar microstructure. Analysis showed that the mechanical properties, in terms of hardness measurements performed at low loads, were significantly different between the two phases. Thus, it was found out that the α phase is softer by about 30% compared to the β phase. The Electrochemical Impedance Spectroscopy technique (EIS) was employed to study the electrochemical behavior in simulated body fluid (SBF). The electrochemical behavior demonstrated that Ti-20Zr alloy exhibits excellent corrosion resistance due to the stable oxide layer formed on its surface. SEM and EDS investigations showed that the surface topography, after electrochemical studies, is characterized by a porous film with increased oxygen content, which might be suitable for the osteoinductive growth of bone. Full article
(This article belongs to the Special Issue Microstructure and Mechanical Behaviour of Structural Materials)
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22 pages, 2382 KiB  
Article
Unraveling the Potential of Attentive Bi-LSTM for Accurate Obesity Prognosis: Advancing Public Health towards Sustainable Cities
by Hina Ayub, Murad-Ali Khan, Syed Shehryar Ali Naqvi, Muhammad Faseeh, Jungsuk Kim, Asif Mehmood and Young-Jin Kim
Bioengineering 2024, 11(6), 533; https://doi.org/10.3390/bioengineering11060533 (registering DOI) - 23 May 2024
Abstract
The global prevalence of obesity presents a pressing challenge to public health and healthcare systems, necessitating accurate prediction and understanding for effective prevention and management strategies. This article addresses the need for improved obesity prediction models by conducting a comprehensive analysis of existing [...] Read more.
The global prevalence of obesity presents a pressing challenge to public health and healthcare systems, necessitating accurate prediction and understanding for effective prevention and management strategies. This article addresses the need for improved obesity prediction models by conducting a comprehensive analysis of existing machine learning (ML) and deep learning (DL) approaches. This study introduces a novel hybrid model, Attention-based Bi-LSTM (ABi-LSTM), which integrates attention mechanisms with bidirectional Long Short-Term Memory (Bi-LSTM) networks to enhance interpretability and performance in obesity prediction. Our study fills a crucial gap by bridging healthcare and urban planning domains, offering insights into data-driven approaches to promote healthier living within urban environments. The proposed ABi-LSTM model demonstrates exceptional performance, achieving a remarkable accuracy of 96.5% in predicting obesity levels. Comparative analysis showcases its superiority over conventional approaches, with superior precision, recall, and overall classification balance. This study highlights significant advancements in predictive accuracy and positions the ABi-LSTM model as a pioneering solution for accurate obesity prognosis. The implications extend beyond healthcare, offering a precise tool to address the global obesity epidemic and foster sustainable development in smart cities. Full article
(This article belongs to the Special Issue Intelligent IoMT Systems for Brain–Computer Interface)
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