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Title:	Synthesis and Biological Evaluation of 3,3-Difluoropyridine-2,4(1H,3H)-dione and 3-Deaza-3-fluorouracil Base and Nucleoside Derivatives
Source:	Journal of Medicinal Chemistry [0022-2623] Robins, Morris yr:2009

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description	1.	Gupta, S. "Antimicrotubular drugs binding to vinca domain of tubulin." Molecular and cellular biochemistry 253.1 (2003): 41-7.
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description	4.	NAGANAWA, A. "Optimization of sulfonamide derivatives as highly selective EP1 receptor antagonists." Bioorganic & medicinal chemistry 14.23 (2006): 7774-7789.
description	5.	Venkatesan, H. "Total Synthesis of SR 121463 A, a Highly Potent and Selective Vasopressin V2 Receptor Antagonist." Journal of organic chemistry 66.11 (2001): 3653-3661.
description	6.	Abd-El-Aziz, Alaa S. "Aliphatic diols in the synthesis of bis(cyclopentadienyliron) arene complexes." Polyhedron 14.12 (1995): 1585-.
description	7.	Baker, Wilson n. "Chelation. V. Hydroxyacetylhydrindenes." Journal of the Chemical Society (1937): 476-.
description	8.	Seebacher, W. "Structural Requirements for the Antiprotozoal Activity of 4-Aminobicyclo[2.2.2]octan-2-ols." Monatshefte für Chemie 137.4 (2006): 471-482.
description	9.	Cassady, John M. "Recent developments in the maytansinoid antitumor agents." Chemical & pharmaceutical bulletin 52.1 (2004): 1-26.
description	10.	Gordaliza, M. "Podophyllotoxin: distribution, sources, applications and new cytotoxic derivatives." Toxicon 44.4 (2004): 441-459.
description	11.	Bai, R. "Direct Photoaffinity Labeling by Dolastatin 10 of the Amino-terminal Peptide of Î²-Tubulin Containing Cysteine 12." The Journal of biological chemistry 279.29 (2004): 30731-30740.
description	12.	Suh, Y. "The structure-activity relationships of mansonone F, a potent anti-MRSA sesquiterpenoid quinone: SAR studies on the C6 and C9 analogs." Bioorganic & medicinal chemistry letters 16.1 (2006): 142-5.
description	13.	Prevost, GP. "Inhibition of human tumor cell growth in vivo by an orally bioavailable inhibitor of human farnesyltransferase, BIM-46228." International journal of cancer 91.5 (2001): 718-722.
description	14.	Brezova, V. "Role of radicals and singlet oxygen in photoactivated DNA cleavage by the anticancer drug camptothecin: An electron paramagnetic resonance study." The journal of physical chemistry. B, Condensed matter, materials, surfaces, interfaces & biophysical 107.10 (2003): 2415-2425.
description	15.	Jordan, Leslie A. "Microtubules as a target for anticancer drugs." Nature reviews. Cancer 4.4 (2004): 253-265.
description	16.	Harrigan, George G. "Medicinal chemistry, metabolic profiling and drug target discovery: A role for metabolic profiling in reverse pharmacology and chemical genetics." Mini reviews in medicinal chemistry 5.1 (2005): 13-20.
description	17.	Gigant, B. "Structural basis for the regulation of tubulin by vinblastine." Nature 435.7041 (2005): 519-522.
description	18.	Soai, K. "Reduction of symmetric and mixed anhydrides of carboxylic acids by sodium borohydride with dropwise addition of methanol." Synthesis 1987.7 (1987): 647-648.
description	19.	Pellegrini, F. "Review: tubulin function, action of antitubulin drugs, and new drug development." Cancer investigation 23.3: 264-273.
description	20.	Johnson, Christopher N. "Palladium(0)-catalyzed arylations using pyrrole- and indole-2-boronic acids." Synlett 9 (1998): 1025-.