SFX by Ex Libris Inc.

Title:	Discovery of Aminothiazole Inhibitors of Cyclin-Dependent Kinase 2: Synthesis, X-ray Crystallographic Analysis, and Biological Activities
Source:	Journal of Medicinal Chemistry [0022-2623] Kim, Kyoung yr:2002

Basic

Full text

Full text available via American Chemical Society Journals

Year:

Volume:

Issue:

Start Page:

Document delivery

Request document via Library/Bibliothek

Users interested in this article also expressed an interest in the following:
description	1.	Stieber, F. "Traceless solid-phase synthesis of 2-aminothiazoles: receptor tyrosine kinase inhibitors with dual selectivity for Tie-2 and VEGFR-2." Angewandte Chemie (International ed.) 41.24 (2002): 4757-61.
description	2.	Ritter, T. "Heterocyclic ring scaffolds as small-molecule cholesterol absorption inhibitors." Organic & biomolecular chemistry 3.19 (2005): 3514-3523.
description	3.	Mavunkel, Babu J. "Indole-based heterocyclic inhibitors of p38 alpha MAP kinase: Designing a conformationally restricted analogue." Bioorganic & medicinal chemistry letters 13.18 (2003): 3087-3090.
description	4.	Kvaerno, L. "An in vitro assay for evaluation of small-molecule inhibitors of cholesterol absorption." Angewandte Chemie (International ed.) 43.35 (2004): 4653-4656.
description	5.	Mazitschek, R. "IBX-mediated oxidation of primary alcohols and aldehydes to form carboxylic acids." Angewandte Chemie (International ed.) 41.21 (2002): 4059-4061.
description	6.	Ritter, T. "Mild cleavage of aryl mesylates. Methanesulfonate as potent protecting group for phenols." Organic letters 6.9 (2004): 1513-1514.
description	7.	Russu, A. "Thiazolidinedione anti-cancer activity: Is inhibition of microtubule assembly implicated?" Medical Hypotheses 68.2 (2007): 343-346.
description	8.	Ritter, T. "Rate acceleration in olefin metathesis through a fluorine-ruthenium interaction." Journal of the American Chemical Society 128.36 (2006): 11768-11769.
description	9.	Mallakpour, S. "Novel and efficient synthesis of 4-substituted-1,2,4-triazolidine-3,5-diones from anilines." Synthetic communications 37.11 (2007): 1927-1934.
description	10.	HELAL, Christopher J. "Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer's disease." Bioorganic & medicinal chemistry letters 14.22 (2004): 5521-5525.
description	11.	Jones, P. "Synthesis and Structure-Activity Relationships of 2-Pyrazinylcarboxamidobenzoates and Î²-Ionylideneacetamidobenzoates with Retinoidal Activity." Journal of medicinal chemistry 41.16 (1998): 3062-5662.
description	12.	Sudibya, H. "Interfacing glycosylated carbon-nanotube-network devices with living cells to detect dynamic secretion of biomolecules." Angewandte Chemie (International ed. in English) 48.15 (2009): 2723-2726.
description	13.	Das, Saibal r. "Total synthesis of phenylpropanoid glycosides, grayanoside A and syringalide B, through a common intermediate." Carbohydrate Research 342.15 (2007): 2309-2315.
description	14.	Ritter, Tobias s. "1,2,4-Oxadiazolidinones as configurationally stable chiral building blocks." Angewandte Chemie (International ed.) 44.6 (2005): 936-8.
description	15.	Waltman, Andrew W. "Rearrangement of N-Heterocylic Carbenes Involving Heterocycle Cleavage." Organometallics 25.18 (2006): 4238-4239.
description	16.	Azoulay, M. "p-Nitrophenyl Î²-D-glucopyranosiduronic analogs as potential substrates for Î²-glucuronidase." Bioorganic & medicinal chemistry letters 7.10 (1997): 1307-.
description	17.	Ritter, T. "Diastereoselective Phenol para-Alkylation: Access to a Cross-Conjugated Cyclohexadienone en Route to Resiniferatoxin." Organic letters 6.23 (2004): 4371-4374.
description	18.	Pansare, Sunil V. "Enantioselective synthesis of Î±-hydroxy-Î³-butyrolactones from an ephedrine-derived morpholine-dione." Tetrahedron 58.44 (2002): 8985-1607.
description	19.	Mallakpour, S. "A novel one-pot synthesis of 4-substituted 1,2,4-triazolidine-3,5-diones." Synlett 8 (2007): 1255-1256.
description	20.	Ritter, T. "A standard system of characterization for olefin metathesis catalysts." Organometallics 25.24 (2006): 5740-5745.