The 2023 MDPI Annual Report has
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16 pages, 3002 KiB  
Article
Anthropometric Profile, Overweight/Obesity Prevalence, and Socioeconomic Impact in Moroccan Children Aged 6–12 Years Old with Autism Spectrum Disorder
by Rachid Touali, Maxime Allisse, Jamal Zerouaoui, El Mahjoub Chakir, Dominic Gagnon, Hung Tien Bui and Mario Leone
Int. J. Environ. Res. Public Health 2024, 21(6), 672; https://doi.org/10.3390/ijerph21060672 (registering DOI) - 24 May 2024
Abstract
Background: In addition to the inherent challenges of their condition, children with autism spectrum disorder (ASD) are also susceptible to the global obesity epidemic. However, concerning the prevalence of obesity within the Moroccan ASD pediatric population, data remain scarce. Methods: A total of [...] Read more.
Background: In addition to the inherent challenges of their condition, children with autism spectrum disorder (ASD) are also susceptible to the global obesity epidemic. However, concerning the prevalence of obesity within the Moroccan ASD pediatric population, data remain scarce. Methods: A total of 258 children (boys = 195) aged 6 to 12 years old (mean = 9.4 ± 1.4) diagnosed with ASD participated in this study. Besides the body mass and height, four significant anthropometric markers for assessing obesity were examined: body mass index (BMI), body surface area (BSA), waist circumference (WC), and waist-to-height ratio (WHtR). Each anthropometric marker was categorized into one of three cardiometabolic risk levels based on the Z-scores and their corresponding percentiles. The distribution was as follows: low risk (≤84th percentile), high risk (85th–94th percentile), and very high risk (≥95th percentile). Subsequently, a multiple regression analysis was employed to develop an algorithm that generates a composite risk score. This score incorporates all the anthropometric variables simultaneously, while also weighting their individual contributions to the cardiometabolic risk. Results: Children with ASD exhibit an anthropometric profile that markedly increases their susceptibility to cardiometabolic issues. While roughly 11% of the general Moroccan child population is overweight or obese, this figure soars to nearly 60% among children with ASD when considering the central adiposity markers. Furthermore, children from middle-class socioeconomic backgrounds display a more than threefold greater risk of developing overweight or obesity compared to their counterparts from lower socioeconomic backgrounds. Conclusions: This study has, for the first time, provided an up-to-date overview of the cardiometabolic risk in Moroccan children with ASD using traditional anthropometric measurements. The primary risk factor is clearly linked to central (abdominal) adiposity, which is recognized as the most deleterious. This study highlights the need to include general and central obesity markers. This study underscores the importance of incorporating both general and central adiposity markers for a more comprehensive assessment, and it emphasizes the need for closer monitoring within this high-risk population. Full article
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9 pages, 277 KiB  
Article
Emotional Eating and Uncontrolled Eating as Risk Predictors for Disordered Eating Attitudes in Candidates for Bariatric Surgery Treated at a Public Hospital in the Amazon
by Jeane Lorena Dias Kikuchi, Manuela Maria de Lima Carvalhal, Millena Borges Inete, Yasmym Dannielle do Espírito Santo Souza, Tainá Martins Moraes, Rafaela Lorena Viana Costa, Rafaelle Dias Gabbay, Carla Cristina Paiva Paracampo and Daniela Lopes Gomes
Nutrients 2024, 16(11), 1600; https://doi.org/10.3390/nu16111600 (registering DOI) - 24 May 2024
Abstract
This study analyzes the eating behavior and factors associated with the presence of disordered eating attitudes in patients undergoing bariatric surgery. It is a cross-sectional, descriptive, and analytical study conducted at a hospital in the Amazon region of Brazil. The Disordered Eating Attitude [...] Read more.
This study analyzes the eating behavior and factors associated with the presence of disordered eating attitudes in patients undergoing bariatric surgery. It is a cross-sectional, descriptive, and analytical study conducted at a hospital in the Amazon region of Brazil. The Disordered Eating Attitude Scale reduced version (DEAS-s) was used to assess the risk of eating disorders and the Three-Factor Eating Questionnaire (TFEQ-R21) was used to characterize eating behavior. A total of 205 patients participated, with a mean age of 37.5 ± 8.6 years. The majority of participants were female (93.7%; p < 0.001), and the mean BMI was 45.3 ± 6.7 kg/m2. It was found that cognitive restraint had the highest mean (52.6 ± 19.9; p < 0.001). As for the DEAS-s, the question with the highest mean response was “spending one or more days without eating or consuming only liquids to lose weight” (2.80 ± 1.99). Female participants had a higher score for emotional eating (p = 0.016). Disordered eating attitudes showed a correlation with emotional eating and uncontrolled eating. These results suggest that candidates for bariatric surgery may have susceptibility to eating disorders. The importance of a multidisciplinary team conducting monitoring during the preoperative period is highlighted. Full article
(This article belongs to the Special Issue Disordered Eating and Lifestyle Studies−2nd Edition)
16 pages, 2816 KiB  
Article
A New Building Information Modelling-Based Approach to Automate Recyclability Rate Calculations for Buildings
by Alireza Fereydooni Eftekhari, Ania Khodabakhshian, Ornella Iuorio, Fulvio Re Cecconi and Bruno Daniotti
Buildings 2024, 14(6), 1521; https://doi.org/10.3390/buildings14061521 (registering DOI) - 24 May 2024
Abstract
To address environmental challenges, the Architecture, Engineering, Construction, and Operations (AECO) industry, which is known for its high resource consumption and waste production, needs to switch to a circular economy (CE). This approach focuses on reducing, recycling, and reusing materials to narrow, slow, [...] Read more.
To address environmental challenges, the Architecture, Engineering, Construction, and Operations (AECO) industry, which is known for its high resource consumption and waste production, needs to switch to a circular economy (CE). This approach focuses on reducing, recycling, and reusing materials to narrow, slow, and close material loops. However, one of the main problems which the AECO industry is still facing is the lack of common, standardized, and automated procedures to consider the recyclability and presence of hazardous materials. To address this problem, this study focuses on extending the recyclability rate from the material to building scale, considering the presence of hazardous materials based on the European Waste Catalogue (EWC), hence defining a new KPI. It adopts Building Information Modelling (BIM) and Industry Foundation Classes (IFCs) and integrates them with bespoke programming in Python to develop a standardized and automated procedure that complies with Italian regulations. The new KPI will help clients and designers to rate the overall recyclability of a building and to choose the best combination of materials and components. The procedure includes data acquisition, transmission, and data/model integration, resulting in practical and trackable measures that could be globally scalable. Scenario analyses are also developed to consider the impact of maintenance attitude on waste production. Full article
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15 pages, 5795 KiB  
Article
Numerical Simulation Study Considering Discontinuous Longitudinal Joints in Soft Soil under Symmetric Loading
by Xianwei He, Xiangyang Xu and Hao Yang
Symmetry 2024, 16(6), 650; https://doi.org/10.3390/sym16060650 (registering DOI) - 24 May 2024
Abstract
In shield tunneling, the joint is one of the most vulnerable parts of the segmental lining. Opening of the joint reduces the overall stiffness of the ring, leading to structural damage and issues such as water leakage. Currently, the Winkler method is commonly [...] Read more.
In shield tunneling, the joint is one of the most vulnerable parts of the segmental lining. Opening of the joint reduces the overall stiffness of the ring, leading to structural damage and issues such as water leakage. Currently, the Winkler method is commonly used to calculate structural deformation, simplifying the interaction between segments and soil as radial and tangential Winkler springs. However, when introducing connection springs or reduction factors to simulate the joint stiffness of segments, the challenge lies in determining the reduction coefficient and the stiffness of the springs. Currently, the hyperstatic reflection method cannot simulate the discontinuity effect at the connection of the tunnel segments, while the state space method overlooks the nonlinear interaction between the tunnel and the soil. Therefore, this paper proposes a numerical simulation method considering the interaction between the tunnel and the soil, which is subjected to compression rather than tension, and the discontinuity of the joints between the segments. The model structure and external load are symmetrical, resulting in symmetrical calculation results. This method is based on the soft soil layers and shield tunnel structures of the Shanghai Metro, and the applicability of the model is verified through deformation calculations using three-dimensional laser scanning point clouds of sections from the Shanghai Metro Line 5. When the subgrade reaction coefficient is 5000 kN/m3, the model can effectively simulate the deformation of operational tunnels. By adjusting the bending stiffness of individual connection springs, we investigate the influence of bending stiffness reduction on the bending moment, radial displacement, and rotational displacement of the ring. The results indicate that a decrease in joint bending stiffness significantly affects the mechanical response of the ring, and the extent and degree of this influence are correlated with the joint position and the magnitude of joint bending stiffness. Full article
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14 pages, 2993 KiB  
Article
Tunable Near-Infrared Transparent Bands Based on Cascaded Fabry–Perot Cavities Containing Phase Change Materials
by Yuchun She, Kaichan Zhong, Manni Tu, Shuyuan Xiao, Zhanxu Chen, Yuehua An, Dejun Liu and Feng Wu
Photonics 2024, 11(6), 497; https://doi.org/10.3390/photonics11060497 (registering DOI) - 24 May 2024
Abstract
In this paper, we construct a near-infrared Fabry–Perot cavity composed of two sodium (Na) layers and an antimony trisulfide (Sb2S3) layer. By cascading two Fabry–Perot cavities, the transmittance peak splits into two transmittance peaks due to the coupling between [...] Read more.
In this paper, we construct a near-infrared Fabry–Perot cavity composed of two sodium (Na) layers and an antimony trisulfide (Sb2S3) layer. By cascading two Fabry–Perot cavities, the transmittance peak splits into two transmittance peaks due to the coupling between two Fabry–Perot modes. We utilize a coupled oscillator model to describe the mode coupling and obtain a Rabi splitting of 60.0 meV. By cascading four Fabry–Perot cavities, the transmittance peak splits into four transmittance peaks, leading to a near-infrared transparent band. The near-infrared transparent band can be flexibly tuned by the crystalline fraction of the Sb2S3 layers. In addition, the effects of the layer thickness and incident angle on the near-infrared transparent band and the mode coupling are investigated. As the thickness of the Na layer increases, the coupling strength between the Fabry–Perot modes becomes weaker, leading to a narrower transparent band. As the thickness of the Sb2S3 layer increases, the round-trip propagating of the Sb2S3 layer increases, leading to the redshift of the transparent band. As the incident angle increases, the round-trip propagating of the Sb2S3 layer decreases, leading to the blueshift of the transparent band. This work not only provides a viable route to achieving tunable near-infrared transparent bands, but also possesses potential applications in high-performance display, filtering, and sensing. Full article
(This article belongs to the Special Issue Photonic Crystals: Physics and Devices)
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18 pages, 2521 KiB  
Article
Investigating Endemic Species Conservation Hotspots Based on Species Distribution Models in Swat Region, Hindu Kush Pakistan
by Shawkat Ali, Haidar Ali, Omid Ghadirian Baharanchi, Hassan Sher and Rasoul Yousefpour
Land 2024, 13(6), 737; https://doi.org/10.3390/land13060737 (registering DOI) - 24 May 2024
Abstract
For the effective conservation of plant species, it is imperative to manage habitat loss and fragmentation by establishing a protected area network that comprehensively encompasses their habitat. In this study, we identified the suitable habitats for some endemic plant species in the Swat [...] Read more.
For the effective conservation of plant species, it is imperative to manage habitat loss and fragmentation by establishing a protected area network that comprehensively encompasses their habitat. In this study, we identified the suitable habitats for some endemic plant species in the Swat District, Pakistan, to conduct a thorough analysis of proposed protected areas (hotspot areas). Utilizing data from a recent botanical survey, environmental parameters from World-Clim, and various other sources, we determined the habitat of each species using the MaxEnt species distribution model. The modeled habitat suitability for each species were combined to generate maps illustrating endemic richness (hotspots), as well as to prioritize areas based on conservation value and habitat suitability. Future climate projections spanning from 2000 to 2050 were acquired from the WorldClim database Nineteen bioclimatic variables were assessed, incorporating data from three global climate models: CCSM4, HadGEM2-AO, and MPI-ESM-LR. We modeled seven endemic species from the Swat District and, by combining their maps, found three hotspot areas which show more environmental suitability under future climatic conditions. The future model forecasts a significant decrease in population density by the year 2050. Currently, these species exhibit their highest density along the eastern and southern borders of the valley, particularly in the Karakar, Elum border, Mankial Kalam, and Gabral Kalam areas. The anticipated alterations in density and distribution could have a considerable impact not only on the tree species but also on the associated sub flora. Full article
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11 pages, 657 KiB  
Article
A Comprehensive Approach to PROMs in Elective Orthopedic Surgery: Comparing Effect Sizes across Patient Subgroups
by Ville Äärimaa, Karita Kohtala, Ida Rantalaiho, Elina Ekman, Keijo Mäkelä, Hanna-Stiina Taskinen, Anssi Ryösä, Joel Kostensalo, Saara Meronen and Inari Laaksonen
J. Clin. Med. 2024, 13(11), 3073; https://doi.org/10.3390/jcm13113073 (registering DOI) - 24 May 2024
Abstract
Background: There is limited knowledge regarding the comparative patient-reported outcomes (PROMs) and effect sizes (ESs) across orthopedic elective surgery. Methods: All patient data between January 2020 and December 2022 were collected, and treatment outcomes assessed as a PROM difference between baseline [...] Read more.
Background: There is limited knowledge regarding the comparative patient-reported outcomes (PROMs) and effect sizes (ESs) across orthopedic elective surgery. Methods: All patient data between January 2020 and December 2022 were collected, and treatment outcomes assessed as a PROM difference between baseline and one-year follow-up. The cohort was divided into subgroups (hand, elbow, shoulder, spine, hip, knee, and foot/ankle). The PROM ESs were calculated for each patient separately, and patients with ES > 0.5 were considered responders. Results: In total, 7695 patients were operated on. The mean ES across all patient groups was 1.81 (SD 1.41), and the largest ES was observed in shoulder patients and the smallest in hand patients. Overall, shoulder, hip, and knee patients had a larger ES compared to hand, spine, and foot/ankle patients (p < 0.0001). The proportion of positive responders ranged between 91–94% in the knee, shoulder, and hip, and 69–70% in the hand, spine, and foot/ankle subgroups. Conclusions: The ESs are generally high throughout elective orthopedic surgery. However, based on our institutional observations, shoulder, hip, and knee patients experience larger treatment effects compared to hand, spine, and foot/ankle patients, among whom there are also more non-responders. The expected treatment outcomes should be clearly communicated to patients when considering elective surgery. Because of the study limitations, the results should be approached with some caution. Full article
(This article belongs to the Section Orthopedics)
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16 pages, 3222 KiB  
Article
Effects of Delaying the Storage of ‘Hass’ Avocados under a Controlled Atmosphere on Skin Color, Bioactive Compounds and Antioxidant Capacity
by Daniela Olivares, Pablo A. Ulloa, Cristina Vergara, Ignacia Hernández, Miguel Ángel García-Rojas, Reinaldo Campos-Vargas, Romina Pedreschi and Bruno G. Defilippi
Plants 2024, 13(11), 1455; https://doi.org/10.3390/plants13111455 (registering DOI) - 24 May 2024
Abstract
During ripening, ‘Hass’ avocado skin changes from green to purple/black. Low-temperature storage with a controlled atmosphere (CA) is the most widely used method for avocado storage; however, few studies have simulated this technology and considered the days of regular air (RA) storage prior [...] Read more.
During ripening, ‘Hass’ avocado skin changes from green to purple/black. Low-temperature storage with a controlled atmosphere (CA) is the most widely used method for avocado storage; however, few studies have simulated this technology and considered the days of regular air (RA) storage prior to CA storage. Herein, the effect of delaying the storage of ‘Hass’ avocado (>30% dry matter) in a CA was examined. Long-term storage conditions (5 °C for 50 days) corresponded to (i) regular air storage (RA), (ii) CA (4 kPa O2 and 6 kPa CO2) and (iii) 10 days in RA + 40 days in a CA and (iv) 20 days in RA + 30 days in a CA. Evaluations were performed during storage and at the ready-to-eat (RTE) stage. Skin color remained unchanged during storage, but at the RTE stage, more color development was observed for fruits stored under CA conditions, as these fruits were purple/black (>50%). At the RTE stage, the anthocyanin content increased, and compared to fruit under RA, fruit under a CA contained a five-fold greater content. A 20-day delay between harvest and CA storage increased the fruit softening rate and skin color development after cold storage, reducing the effectiveness of CA as a postharvest technology for extending storage life. Full article
(This article belongs to the Special Issue Postharvest Quality and Physiology of Fruits)
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14 pages, 2820 KiB  
Article
From Ethnobotany to Biotechnology: Wound Healing and Anti-Inflammatory Properties of Sedum telephium L. In Vitro Cultures
by Vanessa Dalla Costa, Anna Piovan, Raffaella Filippini and Paola Brun
Molecules 2024, 29(11), 2472; https://doi.org/10.3390/molecules29112472 (registering DOI) - 24 May 2024
Abstract
Sedum telephium is a succulent plant used in traditional medicine, particularly in Italy, for its efficacy in treating localized inflammation such as burns, warts, and wounds. Fresh leaves or freshly obtained derivatives are directly applied to the injuries for these purposes. However, challenges [...] Read more.
Sedum telephium is a succulent plant used in traditional medicine, particularly in Italy, for its efficacy in treating localized inflammation such as burns, warts, and wounds. Fresh leaves or freshly obtained derivatives are directly applied to the injuries for these purposes. However, challenges such as the lack of microbiologically controlled materials and product standardization prompted the exploration of more controlled biotechnological alternatives, utilizing in vitro plant cell cultures of S. telephium. In the present study, we used HPLC-DAD analysis to reveal a characteristic flavonol profile in juices from in vivo leaves and in vitro materials mainly characterized by several kaempferol and quercetin derivatives. The leaf juice exhibited the highest content in total flavonol and kaempferol derivatives, whereas juice from callus grown in medium with hormones and callus suspensions showed elevated levels of quercetin derivatives. The in vitro anti-inflammatory and wound-healing assays evidenced the great potential of callus and suspension cultures in dampening inflammation and fostering wound closure, suggesting quercetin may have a pivotal role in biological activities. Full article
(This article belongs to the Special Issue Bioactivity of Natural Compounds: From Plants to Humans)
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20 pages, 1524 KiB  
Systematic Review
High Serum Phosphate Is Associated with Cardiovascular Mortality and Subclinical Coronary Atherosclerosis: Systematic Review and Meta-Analysis
by Carolina Torrijo-Belanche, Belén Moreno-Franco, Ainara Muñoz-Cabrejas, Naiara Calvo-Galiano, José Antonio Casasnovas, Carmen Sayón-Orea and Pilar Guallar-Castillón
Nutrients 2024, 16(11), 1599; https://doi.org/10.3390/nu16111599 (registering DOI) - 24 May 2024
Abstract
(1) Background: Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide. The aim of the study was to examine the existing published results of the association between elevated serum phosphate concentrations and cardiovascular mortality, along with the CVD incidence and subclinical coronary [...] Read more.
(1) Background: Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide. The aim of the study was to examine the existing published results of the association between elevated serum phosphate concentrations and cardiovascular mortality, along with the CVD incidence and subclinical coronary atherosclerosis, in primary prevention among non-selected samples of the general population. (2) Methods: A systematic review and meta-analysis were carried out using literature obtained from PubMed, SCOPUS, and the Web Of Science until March 2024 and following the PRISMA guidelines. Relevant information was extracted and presented. Random and fixed effects models were used to estimate the pooled odds ratio (OR) and hazard ratio (HR) with their 95% coefficient interval (CI), and I2 was used to assess heterogeneity. (3) Results: Twenty-five studies met our inclusion criteria and were included in the meta-analysis (11 cross-sectional and 14 cohort studies). For cardiovascular mortality, which included 7 cohort studies and 41,764 adults, the pooled HR was 1.44 (95% CIs 1.28, 1.61; I2 0%) when the highest versus the reference level of serum phosphate concentrations were compared. For CVDs, which included 8 cohort studies and 61,723 adults, the pooled HR was 1.12 (95% CIs 0.99, 1.27; I2 51%). For subclinical coronary atherosclerosis, which included 11 cross-sectional studies and 24,820 adults, the pooled OR was 1.44 (95% CIs 1.15, 1.79; I2 88%). (4) Conclusions: The highest serum phosphate concentrations were positively associated with a 44% increased risk of cardiovascular mortality and subclinical coronary atherosclerosis. Full article
(This article belongs to the Special Issue The Role of Diet and Cardiometabolic Risk Factors in Chronic Diseases)
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13 pages, 2768 KiB  
Article
Soil Organic Carbon Dynamics in the Long-Term Field Experiments with Contrasting Crop Rotations
by Tomáš Šimon, Mikuláš Madaras, Markéta Mayerová and Eva Kunzová
Agriculture 2024, 14(6), 818; https://doi.org/10.3390/agriculture14060818 (registering DOI) - 24 May 2024
Abstract
Trends in soil organic carbon (SOC) were analyzed in the soils from the oldest Czech long-term field experiment, the Prague-Ruzyně Long-Term Fertilizer Experiment, conducted on Haplic Luvisol since 1955. The aim of the work was to compare the long-term dynamics of SOC in [...] Read more.
Trends in soil organic carbon (SOC) were analyzed in the soils from the oldest Czech long-term field experiment, the Prague-Ruzyně Long-Term Fertilizer Experiment, conducted on Haplic Luvisol since 1955. The aim of the work was to compare the long-term dynamics of SOC in contrasting crop rotations and different fertilization regimes. The trial design includes two crop rotations (CR): simple CR with two-year rotation of sugar beet and spring wheat, and multi-crop rotation (MCR) with nine crops. Four fertilization treatments were chosen for SOC analysis: unfertilized control, only mineral fertilization (NPK), farmyard manure application (FYM), as well as FYM and NPK application. SOC content was significantly affected by both fertilization and crop rotation practices. In the simple CR, both the unfertilized control and the NPK treatment exhibited a consistent decline in SOC content over the study period, with percentages decreasing from an initial 1.33% in 1955 to 1.15% and 1.14%, respectively. Although the FYM and FYM + NPK treatments showed an increase in SOC content in the 1990s, a gradual decline was recorded in the last two decades. This decrease was not observed in MCR: positive C balances were recorded in all treatments within MCR, with the largest increase in SOC stock occurring when NPK was combined with FYM. In contrast, over the last decade, C balances have decreased in simple CR for all treatments except FYM. This trend coincides with changes in the local climate, particularly rising temperatures. The results indicate that diversified crop rotations and FYM fertilization are effective in mitigating the negative impacts of changing environmental conditions on SOC stocks. Full article
(This article belongs to the Special Issue Soil Management for Sustainable Agriculture)
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18 pages, 5042 KiB  
Article
Isolation and Characterization of a Low-Temperature, Cellulose-Degrading Microbial Consortium from Northeastern China
by Jiaoyang Ji, Maia Escobar, Shijia Cui, Wei Zhang, Changjie Bao, Xuhan Su, Gang Wang, Sitong Zhang, Huan Chen and Guang Chen
Microorganisms 2024, 12(6), 1059; https://doi.org/10.3390/microorganisms12061059 (registering DOI) - 24 May 2024
Abstract
The lack of efficient ways to dispose of lignocellulosic agricultural residues is a serious environmental issue. Low temperatures greatly impact the ability of organisms to degrade these wastes and convert them into nutrients. Here, we report the isolation and genomic characterization of a [...] Read more.
The lack of efficient ways to dispose of lignocellulosic agricultural residues is a serious environmental issue. Low temperatures greatly impact the ability of organisms to degrade these wastes and convert them into nutrients. Here, we report the isolation and genomic characterization of a microbial consortium capable of degrading corn straw at low temperatures. The microorganisms isolated showed fast cellulose-degrading capabilities, as confirmed by scanning electron microscopy and the weight loss in corn straw. Bacteria in the consortium behaved as three diverse and functionally distinct populations, while fungi behaved as a single population in both diversity and functions overtime. The bacterial genus Pseudomonas and the fungal genus Thermoascus had prominent roles in the microbial consortium, showing significant lignocellulose waste-degrading functions. Bacteria and fungi present in the consortium contained high relative abundance of genes for membrane components, with amino acid breakdown and carbohydrate degradation being the most important metabolic pathways for bacteria, while fungi contained more genes involved in energy use, carbohydrate degradation, lipid and fatty acid decomposition, and biosynthesis. Full article
(This article belongs to the Section Environmental Microbiology)
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17 pages, 5862 KiB  
Article
HemN2 Regulates the Virulence of Pseudomonas donghuensis HYS through 7-Hydroxytropolone Synthesis and Oxidative Stress
by Yaqian Xiao, Wang Xiang, Xuerui Ma, Donghao Gao, Hasan Bayram, George H. Lorimer, Reza A. Ghiladi, Zhixiong Xie and Jun Wang
Biology 2024, 13(6), 373; https://doi.org/10.3390/biology13060373 (registering DOI) - 24 May 2024
Abstract
Compared to pathogens Pseudomonas aeruginosa and P. putida, P. donghuensis HYS has stronger virulence towards Caenorhabditis elegans. However, the underlying mechanisms haven’t been fully understood. The heme synthesis system is essential for Pseudomonas virulence, and former studies of HemN have focused [...] Read more.
Compared to pathogens Pseudomonas aeruginosa and P. putida, P. donghuensis HYS has stronger virulence towards Caenorhabditis elegans. However, the underlying mechanisms haven’t been fully understood. The heme synthesis system is essential for Pseudomonas virulence, and former studies of HemN have focused on the synthesis of heme, while the relationship between HemN and Pseudomonas virulence were barely pursued. In this study, we hypothesized that hemN2 deficiency affected 7-hydroxytropolone (7-HT) biosynthesis and redox levels, thereby reducing bacterial virulence. There are four hemN genes in P. donghuensis HYS, and we reported for the first time that deletion of hemN2 significantly reduced the virulence of HYS towards C. elegans, whereas the reduction in virulence by the other three genes was not significant. Interestingly, hemN2 deletion significantly reduced colonization of P. donghuensis HYS in the gut of C. elegans. Further studies showed that HemN2 was regulated by GacS and participated in the virulence of P. donghuensis HYS towards C. elegans by mediating the synthesis of the virulence factor 7-HT. In addition, HemN2 and GacS regulated the virulence of P. donghuensis HYS by affecting antioxidant capacity and nitrative stress. In short, the findings that HemN2 was regulated by the Gac system and that it was involved in bacterial virulence via regulating 7-HT synthesis and redox levels were reported for the first time. These insights may enlighten further understanding of HemN-based virulence in the genus Pseudomonas. Full article
(This article belongs to the Section Microbiology)
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20 pages, 3583 KiB  
Article
FSN-YOLO: Nearshore Vessel Detection via Fusing Receptive-Field Attention and Lightweight Network
by Na Du, Qing Feng, Qichuang Liu, Hui Li and Shikai Guo
J. Mar. Sci. Eng. 2024, 12(6), 871; https://doi.org/10.3390/jmse12060871 (registering DOI) - 24 May 2024
Abstract
Vessel detection is critical for ensuring maritime transportation and navigational safety, creating a pressing need for detection methodologies that are more efficient, precise, and intelligent in the maritime domain. Nonetheless, accurately detecting vessels across multiple scales remains challenging due to the diversity in [...] Read more.
Vessel detection is critical for ensuring maritime transportation and navigational safety, creating a pressing need for detection methodologies that are more efficient, precise, and intelligent in the maritime domain. Nonetheless, accurately detecting vessels across multiple scales remains challenging due to the diversity in vessel types and locations, similarities in ship hull shapes, and disturbances from complex environmental conditions. To address these issues, we introduce an innovative FSN-YOLO framework that utilizes enhanced YOLOv8 with multi-layer attention feature fusion. Specifically, FSN-YOLO employs the backbone structure of FasterNet, enriching feature representations through super-resolution processing with a lightweight Convolutional Neural Network (CNN), thereby achieving a balance between processing speed and model size without compromising accuracy. Furthermore, FSN-YOLO uses the Receptive-Field Attention (RFA) mechanism to adaptively fine-tune the feature responses between channels, significantly boosting the network’s capacity to capture critical information and, in turn, improve the model’s overall performance and enrich the discriminative feature representation of ships. Experimental validation on the Seaship7000 dataset showed that, compared to the baseline YOLOv8l approach, FSN-YOLO considerably increased accuracy, recall rates, and [email protected]:0.95 by absolute margins of 0.82%, 1.54%, and 1.56%, respectively, positioning it at the forefront of current state-of-the-art models. Full article
(This article belongs to the Special Issue Unmanned Marine Vehicles: Navigation, Control and Sensing)
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14 pages, 3333 KiB  
Article
Spectrally Tunable Lead-Free Perovskite Rb2ZrCl6:Te for Information Encryption and X-ray Imaging
by Guoxue Pan, Mingqing Li, Xiaotong Yu, Yuanhao Zhou, Minghui Xu, Xinxin Yang, Zhan Xu, Qianli Li and He Feng
Materials 2024, 17(11), 2530; https://doi.org/10.3390/ma17112530 (registering DOI) - 24 May 2024
Abstract
A series of lead-free Rb2ZrCl6:xTe4+ (x = 0%, 0.1%, 0.5%, 1.0%, 2.0%, 3.0%, 5.0%, 10.0%) perovskite materials were synthesized through a hydrothermal method in this work. The substitution of Te4+ for Zr in Rb [...] Read more.
A series of lead-free Rb2ZrCl6:xTe4+ (x = 0%, 0.1%, 0.5%, 1.0%, 2.0%, 3.0%, 5.0%, 10.0%) perovskite materials were synthesized through a hydrothermal method in this work. The substitution of Te4+ for Zr in Rb2ZrCl6 was investigated to examine the effect of Te4+ doping on the spectral properties of Rb2ZrCl6 and its potential applications. The incorporation of Te4+ induced yellow emission of triplet self-trapped emission (STE). Different luminescence wavelengths were regulated by Te4+ concentration and excitation wavelength, and under a low concentration of Te4+ doping (x ≤ 0.1%), different types of host STE emission and Te4+ triplet state emission could be achieved through various excitation energies. These luminescent properties made it suitable for applications in information encryption. When Te4+ was doped at high concentrations (x ≥ 1%), yellow triplet state emission of Te4+ predominated, resulting in intense yellow emission, which stemmed from strong exciton binding energy and intense electron-phonon coupling. In addition, a Rb2ZrCl6:2%Te4+@RTV scintillating film was fabricated and a spatial resolution of 3.7 lp/mm was achieved, demonstrating the potential applications of Rb2ZrCl6:xTe4+ in nondestructive detection and bioimaging. Full article
(This article belongs to the Special Issue Computed Tomography and X-ray Imaging in Material Science)
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16 pages, 35630 KiB  
Article
Modeling and Simulation of a Gas-Exhaust Design for Battery Thermal Runaway Propagation in a LiFePO4 Module
by Songtong Zhang, Xiayu Zhu, Jingyi Qiu, Chengshan Xu, Yan Wang and Xuning Feng
Batteries 2024, 10(6), 176; https://doi.org/10.3390/batteries10060176 (registering DOI) - 24 May 2024
Abstract
The release of flammable gases during battery thermal runaway poses a risk of combustion and explosion, endangering personnel safety. The convective and diffusive properties of the gas make it challenging to accurately measure gas state, complicating the assessment of the battery pack exhaust [...] Read more.
The release of flammable gases during battery thermal runaway poses a risk of combustion and explosion, endangering personnel safety. The convective and diffusive properties of the gas make it challenging to accurately measure gas state, complicating the assessment of the battery pack exhaust design. In this paper, a thermal resistance network model is established, which is used to calculate the battery thermal runaway propagation. Gas accumulation after thermal runaway venting of a LiFeO4 module is studied using ANSYS Fluent under different venting schemes. The results show that the scheme of battery inversion and simultaneous exhaust from the side and bottom of the module is optimal. The methods and results presented can guide the design of LiFeO4 cell pack runners. Full article
(This article belongs to the Section Battery Performance, Ageing, Reliability and Safety)
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18 pages, 10039 KiB  
Article
Engineering the Integration of Titanium and Nickel into Zinc Oxide Nanocomposites through Nanolayered Structures and Nanohybrids to Design Effective Photocatalysts for Purifying Water from Industrial Pollutants
by Osama Saber, Aya Osama, Nagih M. Shaalan and Mostafa Osama
Catalysts 2024, 14(6), 340; https://doi.org/10.3390/catal14060340 (registering DOI) - 24 May 2024
Abstract
Water pollution is one of the main challenges currently facing scientists around the world because of the rapid growth in industrial activities. On this basis, 2D nanolayered and nanohybrid structures, which are based on a ternary system of nickel–titanium–zinc, are considered favorable sources [...] Read more.
Water pollution is one of the main challenges currently facing scientists around the world because of the rapid growth in industrial activities. On this basis, 2D nanolayered and nanohybrid structures, which are based on a ternary system of nickel–titanium–zinc, are considered favorable sources for designing effective nanocomposites for the photocatalytic degradation of industrial pollutants in a short period of time. These nanocomposites were designed by modifying two-dimensional nanolayers to produce a three-dimensional porous structure of multi-doped Ni/Ti-ZnO nanocomposites. Additionally, another additive was produced by constructing nanohybrids of nickel–titanium–zinc combined with a series of hydrocarbons (n-capric acid, myristic acid, stearic acid, suberic acid, and sebacic acid). Energy-dispersive X-ray spectrometry, X-ray diffraction, scanning electron microscopy, infrared spectroscopy, and thermal analyses confirmed the growth of the nanolayered and nanohybrid materials in addition to the production of nanocomposites. The positive role of the dopants (nickel and titanium) in producing an effective photocatalyst was observed through a significant narrowing of the band gap of zinc oxide to 3.05–3.10 eV. Additionally, the high photocatalytic activity of this nanocomposite enabled the complete removal of colored dye from water after 25 min of UV radiation. In conclusion, this study proposes an unconventional approach for designing new optical nanocomposites for purifying water. Additionally, it suggests a novel supporting method for designing new kinds of nanohybrids based on multi-metals and organic acids. Full article
(This article belongs to the Special Issue Design and Synthesis of Nanostructured Catalysts, 2nd Edition)
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13 pages, 4329 KiB  
Article
Hydraulic Connectiveness Metric for the Analysis of Criticality in Water Distribution Networks
by Malvin S. Marlim and Doosun Kang
Water 2024, 16(11), 1498; https://doi.org/10.3390/w16111498 (registering DOI) - 24 May 2024
Abstract
Capturing the criticality of a water distribution network (WDN) is difficult because of its many constituent factors. In terms of operation, the arrangement of demand nodes and how they connect have a significant influence. This study aims to integrate hydraulic and topologic aspects [...] Read more.
Capturing the criticality of a water distribution network (WDN) is difficult because of its many constituent factors. In terms of operation, the arrangement of demand nodes and how they connect have a significant influence. This study aims to integrate hydraulic and topologic aspects into a single criticality measure by adapting the structural hole influence matrix concept. This method applies the nodal demand to the corresponding pipes to construct a weighted network. The matrix stores each node’s local and global connection information, and the criticality value is then assigned based on the adjacency information. The criticality value can reveal the locations in terms of nodes or pipes that are vital for maintaining a network’s level of service. By analyzing pipe-failure scenarios, the criticality value can be related to the loss of performance. Assessing the nodal criticality change behavior under an increased stress scenario can help uncover the impacted areas. The metric for district metered area (DMA) creation demonstrates its potential as a weighting to be considered. This unified criticality metric enables the evaluation of nodes and pipes in a WDN, thereby enabling resilient and sustainable development planning. Full article
(This article belongs to the Special Issue Sustainable Management of Water Distribution Systems)
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10 pages, 2881 KiB  
Case Report
Diffusion-Weighted Magnetic Resonance Imaging (dMRI) and Cochlear Implant Outcomes in Axonal Auditory Neuropathy: A Case Report
by Gary Rance, Raoul Wills, Andrew Kornberg and Julien Zanin
J. Clin. Med. 2024, 13(11), 3072; https://doi.org/10.3390/jcm13113072 (registering DOI) - 24 May 2024
Abstract
Background: Progressive auditory dysfunction is common in patients with generalized neurodegenerative conditions, but clinicians currently lack the diagnostic tools to determine the location/degree of the pathology and, hence, to provide appropriate intervention. In this study, we present the white-matter microstructure measurements derived from [...] Read more.
Background: Progressive auditory dysfunction is common in patients with generalized neurodegenerative conditions, but clinicians currently lack the diagnostic tools to determine the location/degree of the pathology and, hence, to provide appropriate intervention. In this study, we present the white-matter microstructure measurements derived from a novel diffusion-weighted magnetic resonance imaging (dMRI) technique in a patient with axonal auditory neuropathy and consider the findings in relation to the auditory intervention outcomes. Methods: We tracked the hearing changes in an adolescent with Riboflavin Transporter Deficiency (Type 2), evaluating the sound detection/discrimination, auditory evoked potentials, and both structural- and diffusion-weighted MRI findings over a 3-year period. In addition, we explored the effect of bilateral cochlear implantation in this individual. Results: Between the ages of 15 years and 18 years, the patient showed a complete loss of functional hearing ability. The auditory brainstem response testing indicated an auditory neuropathy with evidence of normal cochlear function but disrupted auditory neural activity. While three structural MRI assessments across this period showed a clinically normal cochleovestibular anatomy, the dMRI evaluation revealed a significant loss of fiber density consistent with axonopathy. The subsequent cochlear implant function was affected with the high levels of current required to elicit auditory sensations and concomitant vestibular and facial nerve stimulation issues. Conclusions: The case study demonstrates the ability of dMRI technologies to identify the subtle white-matter microstructure changes in the auditory pathway, which may disrupt the neural function in patients with auditory axonopathy. Full article
(This article belongs to the Special Issue The Journey of Hearing and Hearing-Related Disorders over Time)
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11 pages, 417 KiB  
Article
Home Anxiety Assessment and Influencing Factors among Adolescent Athletes in Yantai City
by Yuxi Chen, Chunming Ye, Yang Lin, Yongjie Ma, Xingyu Zhang and Jiu Wang
Children 2024, 11(6), 628; https://doi.org/10.3390/children11060628 (registering DOI) - 24 May 2024
Abstract
Objective: To understand the prevalence of home-related anxiety among adolescent athletes during the novel coronavirus pandemic and to ascertain the factors influencing this anxiety. Methods: We employed cluster sampling to select 1150 adolescent athletes (aged 8–18 years) from six sports training schools in [...] Read more.
Objective: To understand the prevalence of home-related anxiety among adolescent athletes during the novel coronavirus pandemic and to ascertain the factors influencing this anxiety. Methods: We employed cluster sampling to select 1150 adolescent athletes (aged 8–18 years) from six sports training schools in Yantai City, Shandong Province. Mental health status was assessed and recorded. Chi-square tests and multivariable logistic regression were used to analyze the factors contributing to athletes’ anxiety. Results: The survey revealed a COVID-19 infection rate of 38.23% (437 individuals) with an anxiety score of 40.98 ± 8.20 and an anxiety detection rate of 11.29% (129 individuals) during the COVID-19 epidemic. Female athletes exhibited a higher anxiety rate of 14.40% compared to 8.40% in male athletes. Multivariate analysis identified female gender as a risk factor for anxiety (OR = 1.64), while participation in aquatics emerged as a protective factor (OR = 0.24, 95% CI: 1.08–2.48). Professional training duration exceeding three years increased anxiety risk (OR = 3.05, 95% CI: 1.67–5.58), as did not seeking help during difficulties (OR = 2.59, 95% CI: 1.33–5.01). Interestingly, parental care was linked to increased anxiety risk (OR = 2.44, 95% CI 1.34–4.44), while care from friends was protective (OR = 0.60, 95% CI: 0.36–1.01), which was possibly due to the pressure associated with parental expectations. Conclusions: Adolescent athletes, particularly females and those with extended training durations, exhibit a heightened susceptibility to anxiety. This study also highlights that athletes who proactively seek assistance during challenging situations tend to experience lower anxiety levels. Additionally, a lack of COVID-19 infection and the involvement of concerned parents contribute to reduced anxiety among these young athletes. Full article
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14 pages, 3781 KiB  
Article
Enhancing Spatial Ability: A New Integrated Hybrid Training Approach for Engineering and Architecture Students
by Ronen Porat and Ciprian Ceobanu
Educ. Sci. 2024, 14(6), 563; https://doi.org/10.3390/educsci14060563 (registering DOI) - 24 May 2024
Abstract
Spatial ability (SA) is the mental ability to create, maintain, and manipulate abstract visual representations. Studies have shown that SA is a strong predictor of success in the fields of science, technology, engineering, and mathematics (STEM). More recently, attention has extended to the [...] Read more.
Spatial ability (SA) is the mental ability to create, maintain, and manipulate abstract visual representations. Studies have shown that SA is a strong predictor of success in the fields of science, technology, engineering, and mathematics (STEM). More recently, attention has extended to the field of architecture, a discipline where spatial thinking skills are fundamental, yet students in this field have not been extensively examined in terms of their spatial abilities. Therefore, SA skills are essential for students in engineering and architecture during their initial academic phases. This research was conducted within an interdisciplinary academic college and describes in detail a new integrated and hybrid training program that is part of a recent mixed-methods study. This program was built to effectively enhance the SA of first-year undergraduate students in a cost-effective manner, using a multi-method teaching strategy. The training program spanned more than 20 h across four sessions. This article focuses on the training methodology, encompassing four key phases, and serves as a complementary article to the one that was just published separately, describing the effectiveness of this intervention program as measured using SA standard tests. Notably, in certain scenarios, these phases were combined rather than being standalone independent modules. The traditional teaching method (TTM) lays the foundation for SA knowledge via lectures and collaborative interactions. Subsequently, computer-based learning (CBL), using tools such as SketchUp and GeoGebra, facilitates in-depth virtual geometric exploration. Augmented reality (AR) training offers an immersive learning experience, allowing students to interact with 3D objects in real-world environments. Finally, the building real model (BRM) phase transforms 2D designs into tangible 3D structures. This study highlights the comprehensive training approach, emphasizing the robust learning environment facilitated by integrating these phases as part of the full mixed-methods research. The suggested integrated training program was qualitatively explored through post-intervention evaluations to understand participants’ experiences and perceptions. Full article
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16 pages, 4495 KiB  
Systematic Review
Clinical Outcomes in Scleral Fixation Secondary Intraocular Lens with Yamane versus Suture Techniques: A Systematic Review and Meta-Analysis
by Charles Zhang, Charles Palka, Daniel Zhu, Daniel Lai, Jules Winokur, Treefa Shwani, Margaret M. DeAngelis and Andrew L. Reynolds
J. Clin. Med. 2024, 13(11), 3071; https://doi.org/10.3390/jcm13113071 (registering DOI) - 24 May 2024
Abstract
Background: The purpose of the study is to compare the visual outcomes and complications of sutured scleral fixation (SSF), a traditional and conservative surgical approach, and the newer and faster Yamane technique for secondary intraocular lens placement. Methods: A literature search was performed [...] Read more.
Background: The purpose of the study is to compare the visual outcomes and complications of sutured scleral fixation (SSF), a traditional and conservative surgical approach, and the newer and faster Yamane technique for secondary intraocular lens placement. Methods: A literature search was performed on PubMed, Embase, and Scopus on studies published between 1 July 2017 to 29 September 2023. Outcomes analyzed included the final best corrected visual acuity (BCVA) between 3 and 12 months to assess the effectiveness of the procedure, post-operative month (POM) 1 BCVA to assess the speed of visual recovery, endothelial cell count (ECC), absolute refractive error, surgical duration, and complication rates. Additional subgroup analyses were performed based on surgeon experience with the technique. Single-surgeon studies had an average of 26 procedures performed, whereas multiple-surgeon studies averaged only 9 procedures performed; these were then used to delineate surgeon experience. A sample-size weighted mean difference (MD) meta-analysis was performed across all variables using RevMan 5.4.1; p < 0.05 was considered statistically significant. Results: Thirteen studies with 737 eyes were included: 406 eyes were included in the SSF group, and 331 eyes were included in the Yamane group. There was no significant difference in the final BCVA between groups in both the single-surgeon versus multiple-surgeon studies (MD = −0.01, 95% CI: [−0.06, 0.04], p = 0.73). In the single-surgeon studies, the BCVA at POM1 was significantly improved in the Yamane group compared to SSF (MD = −0.10, 95% CI: [−0.16, −0.04], p = 0.002). In the multiple-surgeon studies, there was no significant difference in BCVA at POM1 (MD = −0.06, 95% CI: [−0.16, 0.04], p = 0.23). The Yamane group had a shorter surgical duration than SSF in both single-surgeon and multiple-surgeon studies (MD = −24.68, 95% CI: [−35.90, −13.46], p < 0.0001). The ECC, refractive error, and complication rates did not significantly differ amongst all groups. Conclusions: The Yamane technique demonstrated similar long-term visual outcomes and complication rates to the traditional SSF. Visual recovery was significantly faster in the Yamane group in the single-surgeon studies. The operative times were shorter across all Yamane groups. Based on these findings, it is advisable to consider the Yamane technique as a viable, and perhaps preferable, option for patients requiring secondary IOL placement, alongside traditional SSF methods. Full article
(This article belongs to the Section Ophthalmology)
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16 pages, 2666 KiB  
Article
Simultaneous Determination of Four Catechins in Black Tea via NIR Spectroscopy and Feature Wavelength Selection: A Novel Approach
by Yabing Liu, Ke Pan, Zhongyin Liu, Yuqiao Dai, Xueyi Duan, Min Wang and Qiang Shen
Sensors 2024, 24(11), 3362; https://doi.org/10.3390/s24113362 (registering DOI) - 24 May 2024
Abstract
As a non-destructive, fast, and cost-effective technique, near-infrared (NIR) spectroscopy has been widely used to determine the content of bioactive components in tea. However, due to the similar chemical structures of various catechins in black tea, the NIR spectra of black tea severely [...] Read more.
As a non-destructive, fast, and cost-effective technique, near-infrared (NIR) spectroscopy has been widely used to determine the content of bioactive components in tea. However, due to the similar chemical structures of various catechins in black tea, the NIR spectra of black tea severely overlap in certain bands, causing nonlinear relationships and reducing analytical accuracy. In addition, the number of NIR spectral wavelengths is much larger than that of the modeled samples, and the small-sample learning problem is rather typical. These issues make the use of NIRS to simultaneously determine black tea catechins challenging. To address the above problems, this study innovatively proposed a wavelength selection algorithm based on feature interval combination sensitivity segmentation (FIC-SS). This algorithm extracts wavelengths at both coarse-grained and fine-grained levels, achieving higher accuracy and stability in feature wavelength extraction. On this basis, the study built four simultaneous prediction models for catechins based on extreme learning machines (ELMs), utilizing their powerful nonlinear learning ability and simple model structure to achieve simultaneous and accurate prediction of catechins. The experimental results showed that for the full spectrum, the ELM model has better prediction performance than the partial least squares model for epicatechin (EC), epicatechin gallate (ECG), epigallocatechin (EGC), and epigallocatechin gallate (EGCG). For the feature wavelengths, our proposed FIC-SS-ELM model enjoys higher prediction performance than ELM models based on other wavelength selection algorithms; it can simultaneously and accurately predict the content of EC (Rp2 = 0.91, RMSEP = 0.019), ECG (Rp2 = 0.96, RMSEP = 0.11), EGC (Rp2 = 0.97, RMSEP = 0.15), and EGCG (Rp2 = 0.97, RMSEP = 0.35) in black tea. The results of this study provide a new method for the quantitative determination of the bioactive components of black tea. Full article
(This article belongs to the Special Issue Optical Spectroscopy for Sensing, Monitoring and Analysis)
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