Hostname: page-component-848d4c4894-x5gtn Total loading time: 0 Render date: 2024-06-03T12:42:44.996Z Has data issue: false hasContentIssue false

Oscillatory flow and mass transport in a flexible tube

Published online by Cambridge University Press:  26 April 2006

Carolyn A. Dragon
Affiliation:
Biomedical Engineering Department. Robert R. McCormick School of Engineering and Applied Science, Northwestern University, Evanston, IL 60208, USA and Department of Anesthesia. Northwestern University Medical School, Chicago, IL 60611, USA
James B. Grotberg
Affiliation:
Biomedical Engineering Department. Robert R. McCormick School of Engineering and Applied Science, Northwestern University, Evanston, IL 60208, USA and Department of Anesthesia. Northwestern University Medical School, Chicago, IL 60611, USA

Abstract

The mass transport of a diffusible substance during volume-cycled oscillatory flow in a thin-walled viscoelastic tube is studied. A small-amplitude, long-wavelength travelling wave is generated by the oscillatory pressure gradient. Lubrication theory is employed for slow axial variations to derive regular perturbation solutions to the Navier–Stokes equations. The convection–diffusion equation is solved in a similar manner, assuming uniform steady end concentrations and no wall flux. From the velocity and concentration fields, the time-average rate of axial mass transport is calculated, and its dependence on oscillation frequency, tube stiffness, and stroke amplitude is investigated. The general result is that transport is enhanced less for softer tubes than for stiffer ones and that mass flow rate as a function of frequency reaches a local maximal value. The results are related to gas transport in pulmonary airways during high-frequency ventilation.

Type
Research Article
Copyright
© 1991 Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Atabek, H. B. & Lew, H. S. 1966 Wave propagation through a viscous incompressible fluid contained in an initially stressed elastic tube. Biophys. J. 6, 481503.Google Scholar
Bohn, D. J., Mlyasaka, K., Marchak, E. B., Thompson, W. K., Froese, A. B. & Bryan, A. C. 1980 Ventilation by high-frequency oscillation. J. Appl. Physiol. 48, 710716.Google Scholar
Chatwin, P. C. 1975 On the longitudinal dispersion of passive contaminant in oscillatory flows in tubes. J. Fluid Mech. 71, 513527.Google Scholar
Croteau, J. R. & Cook, C. D. 1961 Volume-pressure and length-tension measurements in human tracheal and bronchial segments. J. Appl. Physiol. 16, 170172.Google Scholar
Eckman, D. M. & Grotberg, J. B. 1988 Oscillatory flow and mass transport, in a curved tube. J. Fluid Mech. 188, 509527.Google Scholar
Gaver, D. P. & Grotberg, J. B. 1986 An experimental investigation of oscillating flow in a tapered channel. J. Fluid Mech. 172, 4761.Google Scholar
Gavriely, N., Shee, T. R., Cugell, D. W. & Grotberg, J. B. 1989 Flutter in flow-limited collapsible tubes: a mechanism for generation of wheezes. J. Appl. Physiol. 66, 22512261.Google Scholar
Gavriely, N., Solway, J., Drazen, J. M., Slutsky, A. S., Brown, R., Loring, S. H. & Ingram, R. H. 1985 Radiographic visualization of airway wall movement during oscillatory flow in dogs. J. Appl. Physiol. 58, 645652.Google Scholar
Godleski, D. A. & Grotberg, J. B. 1988 Convection-diffusion interaction for oscillatory flow in a tapered tube. J. Biomech. Engng 110, 283291.Google Scholar
Ghotberg, J. B. 1984 Volume-cycled oscillatory flow in a tapered channel. J. Fluid Mech. 141, 249264.Google Scholar
Harris, H. G. & Goren, S. L. 1967 Axial diffusion in a cylinder with pulsed flow. Chem. Engng Sci. 22, 15711576.Google Scholar
Joshi, C. H., Kamm, R. D., Brazen, J- M. & Slutsky, A. S. 1983 An experimental study of gas exchange in laminar oscillatory flow. J. Fluid Mech. 133, 245254.Google Scholar
Martin, H. B. & Proctor, D. F. 1958 Pressure-volume measurements on dog bronchi. J. Appl. Physiol. 13, 337343.Google Scholar
Mitzner, W., Permutt, S. & Wienmann, G. 1983 A model of airway gas transport during high frequency ventilation. Ann. Biomed. Engng 11, 61.Google Scholar
Paloski, W. H., Slosberg, R. B. & Kamm, R. D. 1987 Effects of gas properties and waveform asymmetry on gas transport in a branching tube network. J. Appl. Physiol. 62, 892901.Google Scholar
Pedley, T. J. & Kamm, R. D. 1988 The effect of secondary motion on axial transport in oscillatory tube flow. J. Fluid Mech. 193, 347367.Google Scholar
Rieke, H., Hook, C. & Meyer, M. 1983 Pulmonary gas exchange during high frequency ventilation in dogs. Respir. Physiol. 54, 117.Google Scholar
Rossing, T. H., Slutsky, A. S., Lehr, J. L., Drinker, P. A., Kamm, R. D. & Drazen, J. M. 1981 Tidal volume and frequency dependence of carbon dioxide elimination by high frequency ventilation. New Engl. J. Med. 305, 13751379.Google Scholar
Sharp, M. K., Kamm, R. D., Shapiro, A. H., Kimmel, E. & Karniadakis, G. E. 1991 Dispersion in a curved tube during oscillatory flow. J. Fluid Mech. 223, 537563.Google Scholar
Simon, B. A., Weinmann, G. G. & Mitzner, W. 1984 Mean airway pressure and alveolar pressure during high-frequency ventilation. J. Appl. Physiol. 57, 10691078.Google Scholar
Slutsky, A. S., Drazen, J. M., Ingram, R. H., Kamm, R. D., Shapiro, A. H., Fredberg, J. J., Loring, S. H. & Lehr, J. 1980 Effective pulmonary ventilation with small-volume oscillations at high frequency. Science 209, 609611.Google Scholar
Tarbell, J. M., Ultman, J. S. & Durlofsky, L. 1982 Oscillatory dispersion in a branching tube network. J. Biomech. Engng 104, 338342.Google Scholar
Watson, E. J. 1983 Diffusion in oscillatory pipe flow. J. Fluid Mech. 133, 233244.Google Scholar