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Can normal mode analysis reveal the geometry of the L550 chromophore of bacteriorhodopsin?

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Abstract

We discuss to what extent recent vibrational spectra of 14-2H, 15-2H and 14,15-2H isotopically labelled L550 provide evidence for the occurrence of 13-cis, 14-s-trans or 13-cis, 14-s-cis chromophore structures in bacteriorhodopsin's photocycle. The discussion is based on a quantum chemical (MNDO) vibrational analysis of four molecular fragments as models for the retinal chromophore in bacteriorhodopsin.

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Authors and Affiliations

  1. Physik-Department, Technische Universität München, James-Franck-Strasse, D-8046, Garching, Federal Republic of Germany

    M. F. Großjean, P. Tavan & K. Schulten

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  1. M. F. Großjean
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  2. P. Tavan
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  3. K. Schulten
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Großjean, M.F., Tavan, P. & Schulten, K. Can normal mode analysis reveal the geometry of the L550 chromophore of bacteriorhodopsin?. Eur Biophys J 16, 341–349 (1989). https://doi.org/10.1007/BF00257882

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  • DOI: https://doi.org/10.1007/BF00257882

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