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Prolonged action of drugs in rats with flavonoid-deficiency

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Summary

In flavonoid-deficient Wistar-rats, the action of caffeine, harmine, hexobarbital, morphine and pentobarbital is enhanced. In contrast, the thiopental sleeping time is shortened. These observations may indicate impaired drug metabolism as a consequence of the flavonoid-deficiency state.

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Authors and Affiliations

  1. Abteilung für Pharmakologie der Medizinischen Hochschule, Ratzeburger Allee 160, D-2400, Lübeck, Federal Republic of Germany

    G. Seidel & W. Endell

Authors
  1. G. Seidel
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  2. W. Endell
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Seidel, G., Endell, W. Prolonged action of drugs in rats with flavonoid-deficiency. Experientia 34, 1614–1615 (1978). https://doi.org/10.1007/BF02034708

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  • DOI: https://doi.org/10.1007/BF02034708

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