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X-irradiation of mice in early fetal period influences dose-dependently sex ratio of offspring until weaning

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Summary

Fractionated X-irradiation of mouse fetuses on gestation days 11–13 resulted in a significantly increased postnatal mortality of female litters. This occurred only at 3×110 rad, which was the threshold for the formation of typical neuroepithelial, rosette-like malformations.

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Authors and Affiliations

  1. Abteilung Nuklearbiologie und Abteilung Zellchemie der Gesellschaft für Strahlen- und Umweltforschung, D-8042 Neuherberg, München, Federal Republic of Germany

    W. Schmahl, E. Senft, L. Weber & H. Kriegel

Authors
  1. W. Schmahl
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  2. E. Senft
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  3. L. Weber
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  4. H. Kriegel
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Additional information

We are greatly indebted for the technical assistance of Miss C. Gutmann, Mrs I. Hempfling and Mrs K. Pfaff.

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Schmahl, W., Senft, E., Weber, L. et al. X-irradiation of mice in early fetal period influences dose-dependently sex ratio of offspring until weaning. Experientia 35, 541–543 (1979). https://doi.org/10.1007/BF01922758

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  • DOI: https://doi.org/10.1007/BF01922758

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