Summary
Mouse embryos on day 9 of gestation were exposed in utero to 90 rad X-rays. At different time intervals after treatment the eye primordia were examined for cell death. The irradiation caused an altered necrosis pattern compared with day 8, and massive cell killing during a limited time period. The rapid recovery from the pronounced damage points to a high restitution efficiency of the involved tissue.
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Supported by the Swiss National Foundation for Scientific Research. The technical assistance of Mrs E. Frei is gratefully acknowledged.
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Balla, I., Michel, C. & Fritz-Niggli, H. Cellular damage and recovery of the early developing mouse eye following low dose irradiation. II. X-Rays on day 9 of gestation. Experientia 39, 95–96 (1983). https://doi.org/10.1007/BF01960648
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DOI: https://doi.org/10.1007/BF01960648