Skip to main content
Log in

Cellular damage and recovery of the early developing mouse eye following low dose irradiation. II. X-Rays on day 9 of gestation

  • Short Communications
  • Genetics, Developmental Biology, Aging
  • Published:
Experientia Aims and scope Submit manuscript

Summary

Mouse embryos on day 9 of gestation were exposed in utero to 90 rad X-rays. At different time intervals after treatment the eye primordia were examined for cell death. The irradiation caused an altered necrosis pattern compared with day 8, and massive cell killing during a limited time period. The rapid recovery from the pronounced damage points to a high restitution efficiency of the involved tissue.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Refences

  1. Balla, I., Michel, C., and Fritz-Niggli, H., Experientia37 (1981) 1105.

    Article  CAS  PubMed  Google Scholar 

  2. Saunders, Jr, J.W., Science154 (1966) 604.

    Article  PubMed  Google Scholar 

  3. Hughes, A.F.W., Biol. Rev.51, (1976) 143.

    Article  CAS  PubMed  Google Scholar 

  4. Brent, R.L., Teratology21 (1980) 281.

    Article  CAS  PubMed  Google Scholar 

  5. Rugh, R., Radiology99 (1971) 433.

    Article  CAS  PubMed  Google Scholar 

  6. Fränz, J., in: Malformations congénitales des mammifères, p. 151. Ed. H. Tuchmann-Duplessis. Masson, Paris 1971.

    Google Scholar 

  7. Wendler, D., Acta hist. leopold.8 (1972) 7.

    Google Scholar 

  8. Michel, C., and Fritz-Niggli, H., in: Late biological effects of ionizing radiation, vol. 2, p. 397. International Atomic Energy Agency, Vienna 1978.

    Google Scholar 

  9. Silver, J., and Hughes, A.F.W., J. comp. Neurol.157 (1974) 281.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Supported by the Swiss National Foundation for Scientific Research. The technical assistance of Mrs E. Frei is gratefully acknowledged.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Balla, I., Michel, C. & Fritz-Niggli, H. Cellular damage and recovery of the early developing mouse eye following low dose irradiation. II. X-Rays on day 9 of gestation. Experientia 39, 95–96 (1983). https://doi.org/10.1007/BF01960648

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01960648

Keywords

Navigation