ExLibris header image
SFX Logo
Title: Dual kinase-bromodomain inhibitors for rationally designed polypharmacology
Source:

Nature Chemical Biology [1552-4450] Ciceri, Pietro yr:2014


Collapse list of basic services Basic
Sorry, no full text available...
Please use the document delivery service (see below)  
Holding information
Holdings in library search engine ALBERT GO
Document delivery
Request document via Library/Bibliothek GO
Users interested in this article also expressed an interest in the following:
1. Volkmer, P. "Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family." Cell 149.1 (2012): 214-231. Link to SFX for this item
2. Trusolino, L. "Compensatory pathways in oncogenic kinase signaling and resistance to targeted therapies: six degrees of separation." Cancer discovery 2.10 (2012): 876-880. Link to SFX for this item
3. Schwede, T. "SWISS-MODEL: An automated protein homology-modeling server." Nucleic acids research 31.13 (2003): 3381-5. Link to Full Text for this item Link to SFX for this item
4. Picaud, Sarah E. "PFI-1 - A highly Selective Protein Interaction Inhibitor Targeting BET bromodomains." Cancer research 73.11 (2013): 3336-3346. Link to SFX for this item
5. Knight, Kevan A. "Targeting the cancer kinome through polypharmacology." Nature Reviews. Cancer 10.2 (2010): 130-137. Link to SFX for this item
6. Chi, P. "Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers." Nature Reviews. Cancer 10.7 (2010): 457-469. Link to SFX for this item
7. Filippakopoulos, P. "Targeting bromodomains: epigenetic readers of lysine acetylation." Nature reviews. Drug discovery 13.5 (2014): 337-356. Link to SFX for this item
8. Denis, Gerald V. "BET domain co-regulators in obesity, inflammation and cancer." Nature Reviews. Cancer 12.7 (2012): 465-477. Link to SFX for this item
9. Filippakopoulos, P. "The bromodomain interaction module." FEBS letters 586.17 (2012): 2692-2704. Link to Full Text for this item Link to SFX for this item
10. Arrowsmith, Cheryl H. "Epigenetic protein families: a new frontier for drug discovery." Nature reviews. Drug discovery 11.5 (2012): 384-400. Link to SFX for this item
11. Pujol, A. "Unveiling the role of network and systems biology in drug discovery." Trends in Pharmacological Sciences 31.3 (2010): 115-123. Link to SFX for this item
12. Crommelin, D. "Pharmaceutical sciences in 2020." Nature Reviews. Drug Discovery 9.2 (2010): 99-100. Link to SFX for this item
13. Arnold, K. "The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling." Bioinformatics 22.2 (2006): 195-201. Link to SFX for this item
14. Hewings, David S. "Progress in the Development and Application of Small Molecule Inhibitors of Bromodomain-Acetyl-lysine Interactions." Journal of medicinal chemistry 55.22 (2012): 9393-9413. Link to Full Text for this item Link to SFX for this item
15. Kowal, M. "Nuclei segmentation for computer-aided diagnosis of breast cancer." International Journal of Applied Mathematics and Computer Science 24.1 (2014): 19-31. Link to SFX for this item
16. Wang, S. "Small organic molecules targeting PCAF bromodomain as potent inhibitors of HIV-1 replication." MedChemComm 4.4 (2013): 737-740. Link to Full Text for this item Link to SFX for this item
17. Zhao, L. "Fragment-based Drug Discovery of 2-thiazolidinones as Inhibitors of the Histone Reader BRD4 Bromodomain." Journal of medicinal chemistry 56.10 (2013): 4294967295-3851. Link to Full Text for this item Link to SFX for this item
18. Musselman, Catherine A. "Perceiving the epigenetic landscape through histone readers." Nature structural & molecular biology 19.12 (2012): 1218-1227. Link to SFX for this item
19. Lito, P. "Relief of Profound Feedback Inhibition of Mitogenic Signaling by RAF Inhibitors Attenuates Their Activity in BRAFV600E Melanomas." Cancer cell 22.5 (2012): 668-682. Link to SFX for this item
20. Oronsky, Bryan T. "Six Degrees of Separation: The Oxygen Effect in the Development of Radiosensitizers." Translational oncology 4.4 (2011): 256-265. Link to Full Text for this item Link to SFX for this item
View More...
View Less...
Select All Clear All

Expand list of advanced services Advanced
A service provided by the Library of the Wissenschaftspark Albert Einstein, Potsdam, Germany.
© 2005 SFX by Ex Libris Inc.