SFX by Ex Libris Inc.

Title:	Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems
Source:	Molecular Cell [1097-2765] Shmakov, Sergey yr:2015

Basic

Sorry, no full text available...

Please use the document delivery service (see below)

Holding information

Holdings in library search engine ALBERT

Document delivery

Request document via Library/Bibliothek

Users interested in this article also expressed an interest in the following:
description	1.	Chylinski, K. "The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems." RNA biology 10.5 (2013): 726-737.
description	2.	Makarova, Kira S. "An updated evolutionary classification of CRISPR–Cas systems." Nature Reviews Microbiology 13.11 (2015): 722-736.
description	3.	Wei, Y. "Cas9 function and host genome sampling in Type II-A CRISPR-Cas adaptation." Genes & development 29.4 (2015): 356-61.
description	4.	Kim, D. "Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells." Nature Methods 12.3 (2015): 237-243.
description	5.	Cheung, A F. "Complete deletion of Apc results in severe polyposis in mice." Oncogene 29.12 (2009): 1857-1864.
description	6.	Doudna, Jennifer A. "The new frontier of genome engineering with CRISPR-Cas9." Science 346.6213 (2014): 96-1258096.
description	7.	Tsai, Shengdar Q. "CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR–Cas9 nuclease off-targets." Nature Methods 14.6 (2017): 607-614.
description	8.	Kim, D. "Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq." Genome research 26.3 (2016): 406-415.
description	9.	Chylinski, K. "Classification and evolution of type II CRISPR-Cas systems." Nucleic acids research 42.10 (2014): 6091-105.
description	10.	Charpentier, E. "A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity." Science 337.6096 (2012): 816-820.
description	11.	Doudna, Jennifer A. "RNA-guided genetic silencing systems in bacteria and archaea." Nature 482.7385 (2012): 331-338.
description	12.	Hale, Caryn R. "RNA-guided RNA cleavage by a CRISPR RNA-Cas protein complex." Cell 139.5 (2009): 945-56.
description	13.	Horvath, P. "CRISPR/Cas, the immune system of bacteria and archaea." Science 327.5962 (2010): 167-170.
description	14.	Guo, J. "pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner." Science 353.6302 (2016): 929-932.
description	15.	Schlosshauer, Peter W. "APC truncation and increased -catenin levels in a human breast cancer cell line." Carcinogenesis 21.7 (2000): 1453-1456.
description	16.	Wiles, Michael V V. "CRISPR-Cas9-mediated genome editing and guide RNA design." Mammalian genome 26.9-10 (2015): 501-510.
description	17.	Sanchez Rivera, Francisco J. "Applications of the CRISPR–Cas9 system in cancer biology." Nature Reviews. Cancer 15.7 (2015): 387-95.
description	18.	Shwartz, V. "Derivation of novel human ground state naive pluripotent stem cells." Nature 504.7479 (2013): 282-286.
description	19.	Fu, Y. "High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells." Nature biotechnology 31.9 (2013): 822-826.
description	20.	Swarts, Daan C. "CRISPR Interference Directs Strand Specific Spacer Acquisition." PLoS ONE 7.4 (2012): 1-.