PD 116, 152, A NOVEL PHENAZINE ANTITUMOR ANTIBIOTIC
DISCOVERY, FERMENTATION, CULTURE CHARACTERIZATION AND BIOLOGICAL ACTIVITY
1986 Volume 39 Issue 2 Pages 192-197
Details
1986 Volume 39 Issue 2 Pages 192-197
A novel phenazine antitumor antibiotic is described, produced by Streptomyces lomondensis subsp. galanosa NRRL 15738. The antibiotic is selectively active versus the bacterium Streptococcus pneumoniae (MIC <0.46 μg/ml); the antitumor activity versus murine P388 leukemia is T/C 149.
