1974 Volume 27 Issue 7 Pages 502-506
A new antibiotic XK-46 is produced optimally at 46°C by a thermophilic Streptomyces sp. MK-46. This antibiotic is a color indicator, red in acidic and blue in alkaline solutions, soluble in organic solvents and slightly soluble in water. XK-46 is active against Gram-positive bacteria and Proteus vulgaris, and strongly inhibits tyrosine hydroxylase activity.