Fluorescent light induces malignant transformation in mouse embryo cell cultures

Science. 1980 Mar 14;207(4436):1209-11. doi: 10.1126/science.7355282.

Abstract

Fluorescent light induced a dose-dependent malignant transformation in mouse C3H10T1/2 cells. A plateau in the dose-response curve for transformation was correlated with that observed with ultraviolet light exposure. The similarity in the two dose-response patterns suggests that similar molecular processes may be involved in the induction of malignant transformation by the two types of radiation.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Cell Survival / radiation effects
  • Cell Transformation, Neoplastic / radiation effects*
  • Cells, Cultured
  • DNA / radiation effects
  • Dose-Response Relationship, Radiation
  • Embryo, Mammalian / radiation effects
  • Fluorescence
  • Light*
  • Mice
  • Pyrimidine Dimers / radiation effects
  • Ultraviolet Rays

Substances

  • Pyrimidine Dimers
  • DNA