Chromosomal assignment of the endogenous proto-oncogene C-abl

Science. 1982 Dec 24;218(4579):1317-9. doi: 10.1126/science.6293057.

Abstract

Abelson murine leukemia virus (A-MuLV) is a replication-defective retrovirus that transforms lymphocytes of the B-cell lineage. This virus is a recombinant between the parental Moloney murine leukemia virus and a cellular gene termed C-abl. By analysis of a series of mouse x Chinese hamster hybrid celllines containing various mouse chromosomes, we have mapped the C-abl gene to mouse chromosome 2.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Abelson murine leukemia virus / genetics*
  • Animals
  • B-Lymphocytes
  • Cell Transformation, Viral
  • Chromosome Mapping
  • Cricetinae
  • Cricetulus
  • Hybrid Cells / analysis
  • Leukemia Virus, Murine / genetics*
  • Mice
  • Oncogenes*