Abstract
Female mice of the C3H strain normally do not reject skin grafts from males of the same strain; however, 40 percent of splenectomized C3H female mice completely rejected C3H male skin grafts applied 2 weeks later. All splenectomized females showed at least transitory signs of graft rejection.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Female
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Graft Rejection*
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Histocompatibility Antigens*
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Immunosuppression Therapy
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Male
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Mice
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Mice, Inbred C3H / immunology
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Skin Transplantation
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Spleen / immunology*
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Transplantation, Homologous
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Y Chromosome
Substances
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Histocompatibility Antigens