The 2023 MDPI Annual Report has
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21 pages, 320 KiB  
Article
Freeing the Will from Neurophilosophy: Voluntary Action in Thomas Aquinas and Libet-Style Experiments
by Daniel D. De Haan
Religions 2024, 15(6), 662; https://doi.org/10.3390/rel15060662 (registering DOI) - 28 May 2024
Abstract
This essay presents a substantive Thomist response to neurophilosophy’s main experimental challenge to free will: the Libet-style experiments on the neural antecedents of conscious voluntary actions. My response to this challenge will disclose that Thomists are rationally justified in rejecting both the conclusions [...] Read more.
This essay presents a substantive Thomist response to neurophilosophy’s main experimental challenge to free will: the Libet-style experiments on the neural antecedents of conscious voluntary actions. My response to this challenge will disclose that Thomists are rationally justified in rejecting both the conclusions of neurophilosophy skeptics of free will, and more fundamentally, the rival philosophical conceptions of voluntary action and free will that were chosen to be operationalized in these neuroscientific experiments. I show how the Thomists’ alternative conception of human action justifies a significantly different interpretation of Libet-style experiments, one which reveals the psychological phenomenon targeted by these experiments is miscategorized as a voluntary action. Full article
(This article belongs to the Special Issue Aquinas and the Sciences: Exploring the Past, Present, and Future)
25 pages, 7555 KiB  
Article
Spatial Heterogeneity and Driving Mechanisms of Cultivated Land Intensive Utilization in the Beibu Gulf Urban Agglomeration, China
by Zhongqiu Zhang, Yufeng Zhang and Xiang Zhang
Sustainability 2024, 16(11), 4565; https://doi.org/10.3390/su16114565 (registering DOI) - 28 May 2024
Abstract
Cultivated land intensive utilization (CLIU) exhibits spatial heterogeneity that is influenced by both natural and anthropogenic factors, with land dissected into different scale systems; however, CLIU has not yet been systematically explored. This study takes the Beibu Gulf urban agglomeration, a national-level model [...] Read more.
Cultivated land intensive utilization (CLIU) exhibits spatial heterogeneity that is influenced by both natural and anthropogenic factors, with land dissected into different scale systems; however, CLIU has not yet been systematically explored. This study takes the Beibu Gulf urban agglomeration, a national-level model area for integrated land and sea development in China, as an example to investigate the spatial heterogeneity of CLIU and explore its driving factors through multiple econometrical and geographical methods, including identifying its underlying mechanisms. The results indicate that (1) the CLIU index is 0.334, its Gini coefficient is 0.183, and its comprehensive level has a low intensity and obvious spatial nonequilibrium characteristics. Hypervariable density (50.33%) and the intraprovincial gap (45.6%) are the main sources. (2) Among the independent effects of single factors, the multiple cropping index (0.57), labor force index (0.489), and intensification of construction land (0.375) exert the most influence on CLIU spatial variation. The interaction effects of two factors primarily manifested as nonlinear enhancements, with the interaction between the labor force index and multiple cropping index being particularly noteworthy (0.859). (3) The geographically weighted regression coefficients reveal that temperature (0.332), multiple cropping index (0.211), and labor force index (0.209) have relatively large and positive impacts on CLIU, while slope (−0.1), precipitation (−0.087), and population urbanization (−0.039) have relatively small and negative impacts; all factors exhibit spatial nonstationarity. The spatial heterogeneity of CLIU in the Beibu Gulf urban agglomeration is characterized by patterns’ nonequilibrium and factors’ nonstationarity. The driving mode of multiple factors on CLIU is manifested as follows: natural factors of cropland utilization provide basic guarantees, internal factors of CLIU provide positive enhancement, and external factors of land intensive utilization provide auxiliary promotion. Full article
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13 pages, 1176 KiB  
Article
Frequent Dietary Multi-Mycotoxin Exposure in UK Children and Its Association with Dietary Intake
by Praosiri Charusalaipong, Margaret-Jane Gordon, Louise Cantlay, Nicosha De Souza, Graham W. Horgan, Ruth Bates and Silvia W. Gratz
Toxins 2024, 16(6), 251; https://doi.org/10.3390/toxins16060251 (registering DOI) - 28 May 2024
Abstract
Mycotoxins are potent fungal toxins that frequently contaminate agricultural crops and foods. Mycotoxin exposure is frequently reported in humans, and children are known to be particularly at risk of exceeding safe levels of exposure. Urinary biomonitoring is used to assess overall dietary exposure [...] Read more.
Mycotoxins are potent fungal toxins that frequently contaminate agricultural crops and foods. Mycotoxin exposure is frequently reported in humans, and children are known to be particularly at risk of exceeding safe levels of exposure. Urinary biomonitoring is used to assess overall dietary exposure to multiple mycotoxins. This study aims to quantify multi-mycotoxin exposure in UK children and to identify major food groups contributing to exposure. Four repeat urine samples were collected from 29 children (13 boys and 16 girls, aged 2.4–6.8 years), and food diaries were recorded to assess their exposure to eleven mycotoxins. Urine samples (n = 114) were hydrolysed with β-glucuronidase, enriched through immunoaffinity columns and analysed by LC-MS/MS for deoxynivalenol (DON), nivalenol (NIV), T-2/HT-2 toxins, zearalenone (ZEN), ochratoxin A (OTA) and aflatoxins. Food diaries were analysed using WinDiet software, and the daily intake of high-risk foods for mycotoxin contamination summarised. The most prevalent mycotoxins found in urine samples were DON (95.6% of all samples), OTA (88.6%), HT-2 toxin (53.5%), ZEN (48.2%) and NIV (26.3%). Intake of total cereal-based foods was strongly positively associated with urinary levels of DON and T-2/HT-2 and oat intake with urinary T-2/HT-2. Average daily mycotoxin excretion ranged from 12.10 µg/d (DON) to 0.03 µg/d (OTA), and co-exposure to three or more mycotoxins was found in 66% of samples. Comparing mycotoxin intake estimates to tolerable daily intakes (TDI) demonstrates frequent TDI exceedances (DON 34.2% of all samples, T-2/HT-2 14.9%, NIV 4.4% and ZEN 5.2%). OTA was frequently detected at low levels. When mean daily OTA intake was compared to the reference value for non-neoplastic lesions, the resulting Margin of Exposure (MoE) of 65 was narrow, indicating a health concern. In conclusion, this study demonstrates frequent exposure of UK children to multiple mycotoxins at levels high enough to pose a health concern if exposure is continuous. Full article
(This article belongs to the Special Issue Human Biomonitoring and Risk Assessment of Mycotoxins)
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12 pages, 262 KiB  
Article
Contact with the Dead in Iceland Past and Present: The Findings of a New Survey of Folk Belief and Experiences of the Supernatural in Iceland
by Terry Gunnell
Religions 2024, 15(6), 661; https://doi.org/10.3390/rel15060661 (registering DOI) - 28 May 2024
Abstract
This article focuses on the figures concerning experiences of and beliefs in possible contacts with the dead amongst Icelandic people that have come to light from three national surveys that were undertaken in 1974, 2006–2007, and 2023, focusing in particular on the most [...] Read more.
This article focuses on the figures concerning experiences of and beliefs in possible contacts with the dead amongst Icelandic people that have come to light from three national surveys that were undertaken in 1974, 2006–2007, and 2023, focusing in particular on the most recent figures. It starts by reviewing the earliest evidence of such beliefs in Iceland (expressed in both Old Icelandic literature and Icelandic folk legends), which evidently laid down the foundations for modern-day beliefs. After listing the main findings of the surveys and noting the changes in belief that appear to have taken place over the last 50 years, the article offers some brief conclusions relating to what seems to have caused not only some obvious gender and age differences in belief and experience, but also differences in figures between urban and rural areas. Full article
(This article belongs to the Special Issue Communication with the Dead)
17 pages, 2089 KiB  
Review
Chronological and Biological Aging in Amyotrophic Lateral Sclerosis and the Potential of Senolytic Therapies
by Anna Roshani Dashtmian, Fereshteh B. Darvishi and William David Arnold
Cells 2024, 13(11), 928; https://doi.org/10.3390/cells13110928 (registering DOI) - 28 May 2024
Abstract
Amyotrophic Lateral Sclerosis (ALS) is a group of sporadic and genetic neurodegenerative disorders that result in losses of upper and lower motor neurons. Treatment of ALS is limited, and survival is 2–5 years after disease onset. While ALS can occur in younger individuals, [...] Read more.
Amyotrophic Lateral Sclerosis (ALS) is a group of sporadic and genetic neurodegenerative disorders that result in losses of upper and lower motor neurons. Treatment of ALS is limited, and survival is 2–5 years after disease onset. While ALS can occur in younger individuals, the risk significantly increases with advancing age. Notably, both sporadic and genetic forms of ALS share pathophysiological features overlapping hallmarks of aging including genome instability/DNA damage, mitochondrial dysfunction, inflammation, proteostasis, and cellular senescence. This review explores chronological and biological aging in the context of ALS onset and progression. Age-related muscle weakness and motor unit loss mirror aspects of ALS pathology and coincide with peak ALS incidence, suggesting a potential link between aging and disease development. Hallmarks of biological aging, including DNA damage, mitochondrial dysfunction, and cellular senescence, are implicated in both aging and ALS, offering insights into shared mechanisms underlying disease pathogenesis. Furthermore, senescence-associated secretory phenotype and senolytic treatments emerge as promising avenues for ALS intervention, with the potential to mitigate neuroinflammation and modify disease progression. Full article
(This article belongs to the Special Issue Genetics and Pathomechanisms of Amyotrophic Lateral Sclerosis (ALS))
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17 pages, 4165 KiB  
Article
Development and Validation of Low-Cost Indoor Air Quality Monitoring System for Swine Buildings
by Elanchezhian Arulmozhi, Anil Bhujel, Nibas Chandra Deb, Niraj Tamrakar, Myeong Yong Kang, Junghoo Kook, Dae Yeong Kang, Eun Wan Seo and Hyeon Tae Kim
Sensors 2024, 24(11), 3468; https://doi.org/10.3390/s24113468 (registering DOI) - 28 May 2024
Abstract
The optimal indoor environment is associated with comfortable temperatures along with favorable indoor air quality. One of the air pollutants, particulate matter (PM), is potentially harmful to animals and humans. Most farms have monitoring systems to identify other hazardous gases rather than PM [...] Read more.
The optimal indoor environment is associated with comfortable temperatures along with favorable indoor air quality. One of the air pollutants, particulate matter (PM), is potentially harmful to animals and humans. Most farms have monitoring systems to identify other hazardous gases rather than PM due to the sensor cost. In recent decades, the application of environmental monitoring systems based on Internet of Things (IoT) devices that incorporate low-cost sensors has elevated extensively. The current study develops a low-cost air quality monitoring system for swine buildings based on Raspberry Pi single-board computers along with a sensor array. The system collects data using 11 types of environmental variables along with temperature, humidity, CO2, light, pressure, and different types of gases, namely PM1, PM2.5, and PM10. The system is designed with a central web server that provides real-time data visualization and data availability through the Internet. It was tested in actual pig barns to ensure stability and functionality. In addition, there was a collocation test conducted by placing the system in two different pig barns to validate the sensor data. The Wilcoxon rank sum test demonstrates that there are no significant differences between the two sensor datasets, as all variables have a p-value greater than 0.05. However, except for carbon monoxide (CO), none of the variables exhibit correlation exceeding 0.5 with PM concentrations. Overall, a scalable, portable, non-complex, low-cost air quality monitoring system was successfully developed within a cost of USD 94. Full article
(This article belongs to the Section Environmental Sensing)
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14 pages, 3474 KiB  
Article
Investigating the Hydrological Relationship between the North Taihang Tunnel and Tianshengqiao Nine Falls
by Xinfeng Wang, Lei Gong, Yuanqing Liu, Yan Wang, Qingang Wang, Mian Song, Pan Xiao and Zheming Shi
Water 2024, 16(11), 1549; https://doi.org/10.3390/w16111549 (registering DOI) - 28 May 2024
Abstract
The impact of a tunnel construction on the groundwater system depends on various parameters and cannot be easily predicted. Along these lines, a deep understanding of the hydrological relationship between tunnels and surface water is considered of vital importance for ensuring safety during [...] Read more.
The impact of a tunnel construction on the groundwater system depends on various parameters and cannot be easily predicted. Along these lines, a deep understanding of the hydrological relationship between tunnels and surface water is considered of vital importance for ensuring safety during railway construction. Upon completion, the North Taihang Tunnel will be one of four extra-long railway tunnels running through the natural ecotope and level-3 protection areas of the Tianshengqiao National Geological Park in Fuping County, Hebei Province. It will be 1 km away from the Tianshengqiao Nine Falls, which is known as a breathtaking landscape feature in Northern China. Local government, societies, and railway design units have raised concerns about whether the construction and operation of the North Taihang Tunnel will affect the Tianshengqiao Nine Falls. To effectively address this issue, in this work, hydrogeological mapping and hydraulic potential-energy calculations were performed in conjunction with hydrochemical and geological structure analyses. The groundwater system units in the study area were divided and the water source of the nine-level waterfall was determined retrospectively. In addition, the recharge of groundwater to the nine-level waterfall was calculated, the hydrogeological properties of the linear structure were analyzed, and the dominant channels of underwater discharge in surface water were compared and studied. The extracted results indicated that: (1) The Tianshengqiao Nine Falls represent a seasonal fall landscape, which is mainly supplied by surface water formed by precipitation and a low proportion of groundwater supply. (2) The water bodies of the North Taihang Tunnel project and Tianshengqiao Nine Falls belong to two independent groundwater systems. (3) No linear structure that connects these two groundwater systems has yet been discovered. It is widely accepted that a minor possibility of hydraulic connection might be present between the North Taihang Tunnel and Tianshengqiao Nine Falls. This work analyzed the water quantity of Nine Falls, determined the hydraulic relationship between the tunnel project and the waterhead of the Nine Falls, and addressed all stakeholder concerns. The conclusions could provide technological support for the scheduled construction projects. Full article
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26 pages, 6159 KiB  
Article
Exploring Oat Husks as Aggregates in Limestone-Based Composites: Effects of Surface Treatments and Binder Selection on Mechanical Performance
by Alysson Larsen Bonifacio and Paul Archbold
Materials 2024, 17(11), 2588; https://doi.org/10.3390/ma17112588 (registering DOI) - 28 May 2024
Abstract
The viability of incorporating agricultural by-products, such as oat husks, not yet explored in limestone-based composites, as more sustainable alternatives for use as novel aggregates may be improved through the adoption of well-known valorisation strategies applied to other plant-based resources. In this context, [...] Read more.
The viability of incorporating agricultural by-products, such as oat husks, not yet explored in limestone-based composites, as more sustainable alternatives for use as novel aggregates may be improved through the adoption of well-known valorisation strategies applied to other plant-based resources. In this context, this work innovates by assessing how treatments on oat husk surfaces and the choice of limestone-based binders impact the mechanical performance of composites. The strategy adopted to achieve these objectives, in addition to carrying out the physical and geometric characterisation of the husks, consists of treating the husks’ surface using washing cycles in water, cement/pozzolan binder, and linseed oil. Furthermore, matrices combining cement, calcium hydroxide Ca(OH)2, and microsilica (SiO2) were used. In conclusion, even though the effects of different binder combinations are inconsistent, coating oat husks—especially with linseed oil—works well in delaying particle degradation and improving mechanical strength compared to untreated particles. Furthermore, when aggregates are substituted with the longer and lamellar particles of oat husk, the impact of the water/cement ratio on mechanical performance and composite workability significantly decreases. Full article
(This article belongs to the Section Construction and Building Materials)
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3 pages, 145 KiB  
Editorial
An Editorial on the Special Issue “Genetic Basis of Human Diseases”
by Mikhail Churnosov
Life 2024, 14(6), 691; https://doi.org/10.3390/life14060691 (registering DOI) - 28 May 2024
Abstract
The role of heredity in the emergence of the overwhelming majority of human diseases is currently considered proven and has significant importance [...] Full article
(This article belongs to the Special Issue Genetic Basis of Human Diseases)
17 pages, 1298 KiB  
Article
ICC-BiFormer: A Deep-Learning Model for Near-Earth Asteroid Detection via Image Compression and Local Feature Extraction
by Yiyang Guo, Yuan Liu and Ru Yang
Electronics 2024, 13(11), 2092; https://doi.org/10.3390/electronics13112092 (registering DOI) - 28 May 2024
Abstract
Detecting near-Earth asteroids (NEAs) is crucial for research in solar system and planetary science. In recent year, deep-learning methods have almost dominated the task. Since NEAs represent only one-thousandth of the pixels in images, we proposed an ICC-BiFormer model that includes an image [...] Read more.
Detecting near-Earth asteroids (NEAs) is crucial for research in solar system and planetary science. In recent year, deep-learning methods have almost dominated the task. Since NEAs represent only one-thousandth of the pixels in images, we proposed an ICC-BiFormer model that includes an image compression and contrast enhancement block and a BiFormer model to capture local features in input images, which is different from previous models based on Convolutional Neural Network (CNN). Furthermore, we utilize a larger input size of the model, which corresponds to the side length of the input image matrix, and design a cropping algorithm to prevent NEAs from being truncated and better divide NEAs and satellites. We apply our ICC-BiFormer model into a dataset of approximately 20,000 streak and 40,000 non-streak images to train a binary classification model. The ICC-BiFormer achieves 99.88% accuracy, which is superior to existing models. Focusing on local features has been proven effective in detecting NEAs. Full article
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12 pages, 1867 KiB  
Article
Genetic Differentiation and Relationship among Castanopsis chinensis, C. qiongbeiensis, and C. glabrifolia (Fagaceae) as Revealed by Nuclear SSR Markers
by Yang Wu, Kai Yang, Xiangying Wen and Ye Sun
Plants 2024, 13(11), 1486; https://doi.org/10.3390/plants13111486 (registering DOI) - 28 May 2024
Abstract
Castanopsis chinensis (Spreng.) Hance is widespread in the subtropical forests of China. Castanopsis qiongbeiensis G.A. Fu and Castanopsis glabrifolia J. Q. Li & Li Chen are limited to the coastal beaches of Wenchang county in the northeast of Hainan Island, and have similar [...] Read more.
Castanopsis chinensis (Spreng.) Hance is widespread in the subtropical forests of China. Castanopsis qiongbeiensis G.A. Fu and Castanopsis glabrifolia J. Q. Li & Li Chen are limited to the coastal beaches of Wenchang county in the northeast of Hainan Island, and have similar morphological characteristics to C. chinensis. It is supposed that C. qiongbeiensis and C. glabrifolia are closely related to C. chinensis. In the present study, the genetic differentiation, gene flow, and genetic relationship of C. chinensis, C. qiongbeiensis, and C. glabrifolia were investigated by using 15 nuclear microsatellite markers; a total of 308 individuals from 17 populations were sampled in the three species. The allelic variation of nuclear microsatellites revealed moderate but significant genetic differentiation (FCT = 0.076) among C. chinensis, C. qiongbeiensis, and C. glabrifolia, and genetic differentiation between C. chinensis and C. glabrifolia was larger than that between C. chinensis and C. qiongbeiensis. Demographic simulations revealed unidirectional gene flow from C. chinensis to C. glabrifolia and C. qiongbeiensis, which highlight dispersal from mainland to island. The isolation effect of Qiongzhou Strait increased the genetic differentiation of species on both sides of the strait; however, the differentiation was diminished by gene flow that occurred during the historical period when Hainan Island was connected to mainland China. Our results supported the argument that C. glabrifolia should be considered an independent species and argued that C. qiongbeiensis should be regarded as an incipient species and independent conservation unit. Full article
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31 pages, 3931 KiB  
Review
Exploring Sustainable Agriculture with Nitrogen-Fixing Cyanobacteria and Nanotechnology
by Taufiq Nawaz, Liping Gu, Shah Fahad, Shah Saud, Bruce Bleakley and Ruanbao Zhou
Molecules 2024, 29(11), 2534; https://doi.org/10.3390/molecules29112534 (registering DOI) - 28 May 2024
Abstract
The symbiotic relationship between nitrogen-fixing cyanobacteria and plants offers a promising avenue for sustainable agricultural practices and environmental remediation. This review paper explores the molecular interactions between nitrogen-fixing cyanobacteria and nanoparticles, shedding light on their potential synergies in agricultural nanotechnology. Delving into the [...] Read more.
The symbiotic relationship between nitrogen-fixing cyanobacteria and plants offers a promising avenue for sustainable agricultural practices and environmental remediation. This review paper explores the molecular interactions between nitrogen-fixing cyanobacteria and nanoparticles, shedding light on their potential synergies in agricultural nanotechnology. Delving into the evolutionary history and specialized adaptations of cyanobacteria, this paper highlights their pivotal role in fixing atmospheric nitrogen, which is crucial for ecosystem productivity. The review discusses the unique characteristics of metal nanoparticles and their emerging applications in agriculture, including improved nutrient delivery, stress tolerance, and disease resistance. It delves into the complex mechanisms of nanoparticle entry into plant cells, intracellular transport, and localization, uncovering the impact on root-shoot translocation and systemic distribution. Furthermore, the paper elucidates cellular responses to nanoparticle exposure, emphasizing oxidative stress, signaling pathways, and enhanced nutrient uptake. The potential of metal nanoparticles as carriers of essential nutrients and their implications for nutrient-use efficiency and crop yield are also explored. Insights into the modulation of plant stress responses, disease resistance, and phytoremediation strategies demonstrate the multifaceted benefits of nanoparticles in agriculture. Current trends, prospects, and challenges in agricultural nanotechnology are discussed, underscoring the need for responsible and safe nanoparticle utilization. By harnessing the power of nitrogen-fixing cyanobacteria and leveraging the unique attributes of nanoparticles, this review paves the way for innovative, sustainable, and efficient agricultural practices. Full article
(This article belongs to the Special Issue Preparation of Innovative Nanomaterials for Water/Air Purification)
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9 pages, 525 KiB  
Article
The Pleural Mesothelioma Cases and Mortality in Portugal in 2014–2020: A Descriptive Study
by Cátia Santos, Ema Sacadura-Leite, Joana Ferreira, Maria dos Anjos Dixe, Philippe Astoul and António Sousa-Uva
Healthcare 2024, 12(11), 1103; https://doi.org/10.3390/healthcare12111103 (registering DOI) - 28 May 2024
Abstract
Background: The incidence and mortality of pleural mesothelioma (PM) reflect the production and consumption of asbestos over time. However, despite the current global concern, these data remain to be known. Objective: Our aim was to carry out a descriptive analysis of PM cases [...] Read more.
Background: The incidence and mortality of pleural mesothelioma (PM) reflect the production and consumption of asbestos over time. However, despite the current global concern, these data remain to be known. Objective: Our aim was to carry out a descriptive analysis of PM cases and mortality from some Portuguese databases between 2014 and 2020. Methods: A retrospective observational study was carried out between 2014 and 2020. Data on the number of PM cases were provided by the Portuguese Cancer Registry, and data on mortality were from the Portuguese Death Certificate Information System. Results: Between 2014 and 2020, 315 cases of PM were reported, with 222 (70.5%) men. The average age of patients was 72.1, with the highest number of cases in patients aged >70 years (n = 198; 62.9%). The highest number of cases was reported in 2018 (n = 62; 19.7%). Regarding mortality, 169 deaths were reported, with 126 (74.6%) men and mostly in individuals aged >70 years (n = 109; 64.5%). It is estimated that around 520 years of potential life were lost. The highest number of deaths occurred in 2015 (n = 33; 19.5%). Conclusion: It is mandatory to reinforce the need for surveillance programs that allow us to gather real and reliable data and eliminate asbestos-related diseases. Full article
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16 pages, 25084 KiB  
Article
SonoNERFs: Neural Radiance Fields Applied to Biological Echolocation Systems Allow 3D Scene Reconstruction through Perceptual Prediction
by Wouter Jansen and Jan Steckel
Biomimetics 2024, 9(6), 321; https://doi.org/10.3390/biomimetics9060321 (registering DOI) - 28 May 2024
Abstract
In this paper, we introduce SonoNERFs, a novel approach that adapts Neural Radiance Fields (NeRFs) to model and understand the echolocation process in bats, focusing on the challenges posed by acoustic data interpretation without phase information. Leveraging insights from the field of optical [...] Read more.
In this paper, we introduce SonoNERFs, a novel approach that adapts Neural Radiance Fields (NeRFs) to model and understand the echolocation process in bats, focusing on the challenges posed by acoustic data interpretation without phase information. Leveraging insights from the field of optical NeRFs, our model, termed SonoNERF, represents the acoustic environment through Neural Reflectivity Fields. This model allows us to reconstruct three-dimensional scenes from echolocation data, obtained by simulating how bats perceive their surroundings through sound. By integrating concepts from biological echolocation and modern computational models, we demonstrate the SonoNERF’s ability to predict echo spectrograms for unseen echolocation poses and effectively reconstruct a mesh-based and energy-based representation of complex scenes. Our work bridges a gap in understanding biological echolocation and proposes a methodological framework that provides a first-order model of how scene understanding might arise in echolocating animals. We demonstrate the efficacy of the SonoNERF model on three scenes of increasing complexity, including some biologically relevant prey–predator interactions. Full article
(This article belongs to the Section Bioinspired Sensorics, Information Processing and Control)
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9 pages, 733 KiB  
Article
Posterior Tibial Artery Blood Flow Velocity Is Increased in Patients with Plantar Heel Pain
by Fumiya Kaneko, Sho Katayama and Shintarou Kudo
J. Clin. Med. 2024, 13(11), 3153; https://doi.org/10.3390/jcm13113153 (registering DOI) - 28 May 2024
Abstract
Background/Objectives: This study aimed to investigate the relationship between posterior tibial artery blood flow velocity and plantar heel pain (PHP). Methods: The PHP group comprised patients diagnosed with plantar fasciitis with plantar heel pain during gait, and the control group comprised [...] Read more.
Background/Objectives: This study aimed to investigate the relationship between posterior tibial artery blood flow velocity and plantar heel pain (PHP). Methods: The PHP group comprised patients diagnosed with plantar fasciitis with plantar heel pain during gait, and the control group comprised healthy participants without plantar heel pain. The peak systolic velocity of the posterior tibial artery was measured using ultrasonography; it was measured three times on each side, and the mean value was calculated. Receiver operating characteristic curve analysis was performed to calculate the peak systolic velocity cutoff value for plantar heel pain. Results: 23 patients (age 58.0 ± 16.5 years; 13 males and 10 females) and 23 healthy participants (age 51.3 ± 17.3 years; 10 males and 13 females) formed the PHP and control groups, respectively. Peak systolic velocity on the affected side was significantly greater in the PHP group (44.1 ± 13.1 cm/s) than in the control group (32.7 ± 5.9 cm/s). No significant difference was observed between the left and right sides in the PHP (7.1 ± 9.8 cm/s) and control (3.7 ± 3.0 cm/s) groups. A cutoff value of 38.2 cm/s was observed on the affected side. Conclusions: We quantified the increase in posterior tibial artery blood flow velocity in patients with plantar heel pain. Peak systolic velocity measurements can aid in quantitatively evaluating these patients. This study was registered as a clinical trial (UMIN000046875) on 1 October 2021. Full article
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15 pages, 1852 KiB  
Article
Aeromonas trota Is Highly Refractory to Acquire Exogenous Genetic Material
by Jorge Erick Otero-Olarra, Gilda Díaz-Cárdenas, Ma Guadalupe Aguilera-Arreola, Everardo Curiel-Quesada and Abigail Pérez-Valdespino
Microorganisms 2024, 12(6), 1091; https://doi.org/10.3390/microorganisms12061091 (registering DOI) - 28 May 2024
Abstract
Aeromonas trota is sensitive to most antibiotics and the sole species of this genus susceptible to ampicillin. This susceptibility profile could be related to its inability to acquire exogenous DNA. In this study, A. trota isolates were analyzed to establish their capacity to [...] Read more.
Aeromonas trota is sensitive to most antibiotics and the sole species of this genus susceptible to ampicillin. This susceptibility profile could be related to its inability to acquire exogenous DNA. In this study, A. trota isolates were analyzed to establish their capacity to incorporate foreign DNA. Fourteen strains were identified as A. trota by multilocus phylogenetic analysis (MLPA). Minimal inhibitory concentrations of antibiotics (MIC) were assessed, confirming the susceptibility to most antibiotics tested. To explore their capacity to be transformed, A. trota strains were used as recipients in different horizontal transfer assays. Results showed that around fifty percent of A. trota strains were able to incorporate pBAMD1-2 and pBBR1MCS-3 plasmids after conjugal transfer. In all instances, conjugation frequencies were very low. Interestingly, several isoforms of plasmid pBBR1MCS-3 were observed in transconjugants. Strains could not receive pAr-32, a native plasmid from A. salmonicida. A. trota strains were unable to receive DNA by means of electroporation, natural transformation or vesiduction. These results confirm that A. trota species are extremely refractory to horizontal gene transfer, which could be associated to plasmid instability resulting from oligomerization or to the presence of defense systems against exogenous genetic material in their genomes. To explain the poor results of horizontal gene transfer (HGT), selected genomes were sequenced and analyzed, revealing the presence of defense systems, which could prevent the stable incorporation of exogenous DNA in A. trota. Full article
(This article belongs to the Special Issue An Update on Aeromonas 2.0)
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16 pages, 858 KiB  
Article
Periodic Transformer Encoder for Multi-Horizon Travel Time Prediction
by Hui-Ting Christine Lin and Vincent S. Tseng
Electronics 2024, 13(11), 2094; https://doi.org/10.3390/electronics13112094 (registering DOI) - 28 May 2024
Abstract
In the domain of Intelligent Transportation Systems (ITS), ensuring reliable travel time predictions is crucial for enhancing the efficiency of transportation management systems and supporting long-term planning. Recent advancements in deep learning have demonstrated the ability to effectively leverage large datasets for accurate [...] Read more.
In the domain of Intelligent Transportation Systems (ITS), ensuring reliable travel time predictions is crucial for enhancing the efficiency of transportation management systems and supporting long-term planning. Recent advancements in deep learning have demonstrated the ability to effectively leverage large datasets for accurate travel time predictions. These innovations are particularly vital as they address both short-term and long-term travel demands, which are essential for effective traffic management and scheduled routing planning. Despite advances in deep learning applications for traffic analysis, the dynamic nature of traffic patterns frequently challenges the forecasting capabilities of existing models, especially when forecasting both immediate and future traffic conditions across various time horizons. Additionally, the area of long-term travel time forecasting still remains not fully explored in current research due to these complexities. In response to these challenges, this study introduces the Periodic Transformer Encoder (PTE). PTE is a Transformer-based model designed to enhance traffic time predictions by effectively capturing temporal dependencies across various horizons. Utilizing attention mechanisms, PTE learns from long-range periodic traffic data for handling both short-term and long-term fluctuations. Furthermore, PTE employs a streamlined encoder-only architecture that eliminates the need for a traditional decoder, thus significantly simplifying the model’s structure and reducing its computational demands. This architecture enhances both the training efficiency and the performance of direct travel time predictions. With these enhancements, PTE effectively tackles the challenges presented by dynamic traffic patterns, significantly improving prediction performance across multiple time horizons. Comprehensive evaluations on an extensive real-world traffic dataset demonstrate PTE’s superior performance in predicting travel times over multiple horizons compared to existing methods. PTE is notably effective in adapting to high-variability road segments and peak traffic hours. These results prove PTE’s effectiveness and robustness across diverse traffic environments, indicating its significant contribution to advancing traffic prediction capabilities within ITS. Full article
(This article belongs to the Special Issue Data-Centric Artificial Intelligence: New Methods for Data Processing)
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9 pages, 1110 KiB  
Article
Relationship between Ball Impact Point, Type of Stroke and Shot Direction in High-Performance Padel
by Jesús Ramón-Llín, Diego Muñoz, Iván Martín-Miguel, José F. Guzmán, Goran Vučković, Rafael Martínez-Gallego and Bernardino Javier Sánchez-Alcaraz
Appl. Sci. 2024, 14(11), 4630; https://doi.org/10.3390/app14114630 (registering DOI) - 28 May 2024
Abstract
This study aimed to analyze the relationship between ball impact point, type of stroke, and shot direction in high-performance padel. A total of 8363 strokes from nine matches of three national tournaments involving a total of 24 male players were subjected to systematic [...] Read more.
This study aimed to analyze the relationship between ball impact point, type of stroke, and shot direction in high-performance padel. A total of 8363 strokes from nine matches of three national tournaments involving a total of 24 male players were subjected to systematic observation. The variables analyzed were type of stroke, shot direction, and ball impact. A descriptive analysis was conducted for each study variable, with a comparison of the variables performed using Pearson’s Chi-Square test, column proportions determined using a Z test according to Bonferroni (p < 0.05), an association established by corrected standardized residuals, and an effect size calculated using Crammer’s V. The results showed that the most-used stroke types were volleys, serves, groundstrokes, and backwall shots (67.6%). The cross-court direction stood out over down-the-line and inside-out directions. Finally, almost two-thirds of the impact point locations were forward. In addition, the type of stroke determined shot direction and ball impact location. Moreover, the ball’s impact location significantly determined shot direction. In conclusion, these results suggest that the ball impact location and the type of stroke provide information from which padel shot direction can be anticipated. Such knowledge may constitute a very important factor affecting performance and success among padel players. Full article
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28 pages, 11761 KiB  
Article
Radiometric Infrared Thermography of Solar Photovoltaic Systems: An Explainable Predictive Maintenance Approach for Remote Aerial Diagnostic Monitoring
by Usamah Rashid Qureshi, Aiman Rashid, Nicola Altini, Vitoantonio Bevilacqua and Massimo La Scala
Smart Cities 2024, 7(3), 1261-1288; https://doi.org/10.3390/smartcities7030053 (registering DOI) - 28 May 2024
Abstract
Solar photovoltaic (SPV) arrays are crucial components of clean and sustainable energy infrastructure. However, SPV panels are susceptible to thermal degradation defects that can impact their performance, thereby necessitating timely and accurate fault detection to maintain optimal energy generation. The considered case study [...] Read more.
Solar photovoltaic (SPV) arrays are crucial components of clean and sustainable energy infrastructure. However, SPV panels are susceptible to thermal degradation defects that can impact their performance, thereby necessitating timely and accurate fault detection to maintain optimal energy generation. The considered case study focuses on an intelligent fault detection and diagnosis (IFDD) system for the analysis of radiometric infrared thermography (IRT) of SPV arrays in a predictive maintenance setting, enabling remote inspection and diagnostic monitoring of the SPV power plant sites. The proposed IFDD system employs a custom-developed deep learning approach which relies on convolutional neural networks for effective multiclass classification of defect types. The diagnosis of SPV panels is a challenging task for issues such as IRT data scarcity, defect-patterns’ complexity, and low thermal image acquisition quality due to noise and calibration issues. Hence, this research carefully prepares a customized high-quality but severely imbalanced six-class thermographic radiometric dataset of SPV panels. With respect to previous approaches, numerical temperature values in floating-point are used to train and validate the predictive models. The trained models display high accuracy for efficient thermal anomaly diagnosis. Finally, to create a trust in the IFDD system, the process underlying the classification model is investigated with perceptive explainability, for portraying the most discriminant image features, and mathematical-structure-based interpretability, to achieve multiclass feature clustering. Full article
(This article belongs to the Special Issue Smart Electronics, Energy, and IoT Infrastructures for Smart Cities)
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19 pages, 10172 KiB  
Review
Synthesis of Thionated Perylenediimides: State of the Art and First Investigations of an Alternative to Lawesson’s Reagent
by Oksana Kharchenko, Anna Hryniuk, Oksana Krupka and Piétrick Hudhomme
Molecules 2024, 29(11), 2538; https://doi.org/10.3390/molecules29112538 (registering DOI) - 28 May 2024
Abstract
Perylenediimides (PDIs) are composed of a central perylene ring, on which are grafted two imide groups at the peri positions. Thionated PDIs are characterized by the substitution of one or more oxygen atoms of these imide functions with sulfur atoms. This structural modification [...] Read more.
Perylenediimides (PDIs) are composed of a central perylene ring, on which are grafted two imide groups at the peri positions. Thionated PDIs are characterized by the substitution of one or more oxygen atoms of these imide functions with sulfur atoms. This structural modification alters the electronic properties with a redshift of the optical absorption accompanied by modification of the charge transport characteristics compared to their non-thionated counterparts. These properties make them suitable candidates for applications in optoelectronic devices, such as organic light-emitting diodes and organic photovoltaics. Moreover, the presence of sulfur atom(s) can favor the promotion of reactive oxygen species production for photodynamic and photothermal therapies. These thionated PDIs can be synthesized through the post-functionalization of PDIs by using a sulfurizing reagent. Nevertheless, the main drawbacks remain the difficulties in adjusting the degree of thionation and obtaining tri- and tetrathionated PDIs. Up to now, this thionation reaction has been described almost exclusively using Lawesson’s reagent. In the current study, we present our first investigations into an alternative reagent to enhance selectivity and achieve a greater degree of thionation. The association of phosphorus pentasulfide with hexamethyldisiloxane (Curphey’s reagent) clearly demonstrated higher reactivity compared with Lawesson’s reagent to attain multi-thionated PDIs. Full article
(This article belongs to the Special Issue Organosulfur and Organoselenium Chemistry)
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19 pages, 12878 KiB  
Article
The Influence of nc-AlCrTiN/α-BN Coatings on Increasing the Durability of WC/Co Cutting Inserts in the Inconel Alloy Machining Process
by Joanna Kacprzyńska-Gołacka, Sylwia Sowa, Rafał Brudnias, Daniel Paćko, Zbigniew Słomka, Artur Piasek, Piotr Wieciński, Witold Habrat, Halina Garbacz, Agnieszka Kopia and Jerzy Smolik
Materials 2024, 17(11), 2587; https://doi.org/10.3390/ma17112587 (registering DOI) - 28 May 2024
Abstract
Anti-wear coatings obtained through PVD methods may significantly increase the durability of cutting tools by impacting their wear mechanisms. This study presents and discusses the results of studies on the impact of the thermal conductivity of PVD coatings on the intensity of the [...] Read more.
Anti-wear coatings obtained through PVD methods may significantly increase the durability of cutting tools by impacting their wear mechanisms. This study presents and discusses the results of studies on the impact of the thermal conductivity of PVD coatings on the intensity of the built-up edge (BUE) and built-up layer (BUL) formation in Inconel 600 alloy machining processes. The authors determine the microstructure, phase structure, mechanical properties (hardness, Young’s modulus, and adhesion), and thermal conductivity of different PVD coatings selected for the purpose of the study and varying in terms of conductivity—i.e., AlCrTiN and AlCrTiN/BN. Machining processes were carried out under controlled conditions using VBGT160404-M3 cutting inserts with AlCrTiN and AlCrTiN/BN coatings deposited on their surface. The authors prove that the adjustment of the thermal conductivity of PVD coatings to the thermal conductivity of the tool and machined materials can help change the direction of heat flow to cool the cutting zone more effectively. The study results presented in this article show that the deposition of the AlCrTiN/BN coating reduces the friction wear on the tool flank by over 70% and lowers the intensity of BUE and BUL formation processes on the face by 10%, compared to the AlCrTiN coating. Full article
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7 pages, 203 KiB  
Brief Report
Associations between Stress Mindset and Changes in Positive Affect during a Speech Task: A Preliminary Study
by Satoshi Horiuchi, Fumiya Takisawa, Akira Tsuda, Shuntaro Aoki, Hisayoshi Okamura, Suguru Iwano, Mio Takii and Kenichiro Yoneda
Psychol. Int. 2024, 6(2), 644-650; https://doi.org/10.3390/psycholint6020039 (registering DOI) - 28 May 2024
Abstract
A stress mindset is an individual’s belief that stress has either enhancing (stress-is-enhancing mindset: SEM) or debilitating (stress-is-debilitating mindset: SDM) consequences. This study examined the associations between SEM and changes in positive affect during a speech task using a sample of 32 Japanese [...] Read more.
A stress mindset is an individual’s belief that stress has either enhancing (stress-is-enhancing mindset: SEM) or debilitating (stress-is-debilitating mindset: SDM) consequences. This study examined the associations between SEM and changes in positive affect during a speech task using a sample of 32 Japanese college students as participants. It was hypothesized that participants with SEM would show a greater increase in positive affect over time than those with SDM. The participants rested for three minutes, prepared for three minutes, delivered a speech about themselves in front of an evaluator and video camera (task period), and again rested for three minutes. Positive affect was measured immediately after the two resting periods and during the speech. The participants were divided into groups of 17 and 15 in the SEM and SDM groups, respectively, based on their stress mindset scores. Both groups were fairly matched concerning age and male/female ratio. Change patterns of positive affect did not differ between the two groups, which did not support the hypothesis. However, positive affect was significantly higher in the SEM group compared with the SDM group. The present results differed from previous findings reported in North America. Inconsistent results are discussed related to differences in the speech task and cross-cultural variations of happiness and coping with stressors between North America and Japan. Full article
14 pages, 1027 KiB  
Article
Optimal Voltage Recovery Learning Control for Microgrids with N-Distributed Generations via Hybrid Iteration Algorithm
by Lüeshi Li, Ruizhuo Song and Shuqing Dong
Electronics 2024, 13(11), 2093; https://doi.org/10.3390/electronics13112093 (registering DOI) - 28 May 2024
Abstract
Considering that the nonlinearity and uncertainty of the microgrid model complicate the derivation and design of the optimal controller, an adaptive dynamic programming (ADP) algorithm is designed to solve the model-free non-zero-sum game. By combining the advantages of policy iteration and value iteration, [...] Read more.
Considering that the nonlinearity and uncertainty of the microgrid model complicate the derivation and design of the optimal controller, an adaptive dynamic programming (ADP) algorithm is designed to solve the model-free non-zero-sum game. By combining the advantages of policy iteration and value iteration, an optimal learning control scheme based on hybrid iteration is constructed to provide stringent real power sharing for the nonlinear and coupled microgrid systems with N-distributed generations. First, using non-zero-sum differential game strategy, a novel distributed secondary voltage recovery consensus optimal control protocol is built using a hybrid iteration method to realize the voltage recovery of microgrids. Then, the data of the system state and input are gathered along a dynamic system trajectory and a data-driven optimal controller learns the game solution without microgrid physics information, enhancing convenience and efficiency in practical applications. Furthermore, the convergence analysis is given in detail, and it is proved that the control protocol can converge to the optimal solution so as to ensure the stability of the voltage recovery of the microgrid system. Convergence analysis proves the convergence of the the protocol to the optimal solution, ensuring voltage recovery stability. Simulation results validate the feasibility and effectiveness of the proposed scheme. Full article
(This article belongs to the Special Issue Intelligent Mobile Robotic Systems: Decision, Planning and Control)
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