Gross primary productivity (GPP), representing organic carbon fixation through photosynthesis, is crucial for developing science-based strategies for sustainable development. Given that the tropical region harbors nearly half of all species, it plays a pivotal role in safeguarding the global environment against climate change and preserving global biodiversity. Thus, investigating changes in vegetation productivity within this region holds substantial practical importance for estimating global vegetation productivity. In this study, we employed an enhanced P model to estimate vegetation GPP in the tropical region from 2001 to 2020, based on which we quantified the spatiotemporal changes and associated mechanisms. The results reveal that the annual mean GPP in the tropical region ranged from 2603.9 to 2757.1 g·cm⁻² a⁻¹, demonstrating an overall apparent increasing trend. Inland areas were mainly influenced by precipitation, while coastal areas were primarily influenced by temperature. Land cover changes, especially conversion to cropland, significantly influence GPP, with deciduous—evergreen forest transitions causing notable decreases. Climate change emerges as the dominant factor affecting GPP, as indicated by the contribution rate analysis. This research interprets the spatiotemporal pattern and mechanisms of GPP in the tropics, offering valuable insights for sustainable ecosystem management. Full article

In drug development, it is not uncommon that an active substance exhibits efficacy in vitro but lacks the ability to specifically reach its target in vivo. As a result, targeted drug delivery has become a primary focus in the pharmaceutical sciences. Since the approval of Doxil^® in 1995, liposomes have emerged as a leading nanoparticle in targeted drug delivery. Their low immunogenicity, high versatility, and well-documented efficacy have led to their clinical use against a wide variety of diseases. That being said, every disease is accompanied by a unique set of physiological conditions, and each liposomal product must be formulated with this consideration. There are a multitude of different targeting techniques for liposomes that can be employed depending on the application. Passive techniques such as PEGylation or the enhanced permeation and retention effect can improve general pharmacokinetics, while active techniques such as conjugating targeting molecules to the liposome surface may bring even further specificity. This review aims to summarize the current strategies for targeted liposomes in the treatment of diseases. Full article

Icons are integral to the signature systems within architectural spaces, serving pivotal roles through human–environment interactions. However, previous icon designs often exhibited a considerable randomness and neglected the needs of visually impaired individuals. To address these issues and to overcome the limitations of the computer-aided design methods, such as most of them focusing only on text design which are not compatible with icons, this study presents an intelligent assistance method named “Universal Colour” for icon colour design based on universal design principles. Such a system enables the rapid generation of icon colour schemes and supports visual and quantitative filtering and comparison during the decision-making process for colour scheme optimization. To assess its usability, fifty-two participants conducted icon colour design experiments using this system, resulting in 87% of the design schemes meeting the universality requirements. The results have demonstrated that Universal Colour has the potential to significantly enhance efficiency and cognitive aspects within the decision-making process for users, regardless of their proficiency in icon design, thereby facilitating the generation of universal icon colour schemes in architectural design. Full article

Three approaches for determining the thermodynamic stability of irreversible processes are described in generalized formulations. The simplest is the Gibbs–Duhem theory, specialized to irreversible trajectories, which uses the concept of virtual displacement in the reverse direction. Its only drawback is that even a trajectory leading to an explosion is identified as a thermodynamically stable motion. In the second approach, we use a thermodynamic Lyapunov function and its time rate from the Lyapunov thermodynamic stability theory (LTS, previously known as CTTSIP). In doing so, we demonstrate that the second differential of entropy, a frequently used Lyapunov function, is useful only for investigating the stability of equilibrium states. Nonequilibrium steady states do not qualify. Without using explicit perturbation coordinates, we further identify asymptotic thermodynamic stability and thermodynamic stability under constantly acting disturbances of unperturbed trajectories as well as of nonequilibrium steady states. The third approach is also based on the Lyapunov function from LTS, but here we additionally use the rates of perturbation coordinates, based on the Gibbs relations and without using their explicit expressions, to identify not only asymptotic thermodynamic stability but also thermodynamic stability under constantly acting disturbances. Only those trajectories leading to an infinite rate of entropy production (unstable states) are excluded from this conclusion. Finally, we use these findings to formulate the Fourth Law of thermodynamics based on the thermodynamic stability. It is a comprehensive statement covering all nonequilibrium trajectories, close to as well as far from equilibrium. Unlike previous suggested “fourth laws”, this one meets the same level of generality that is associated with the original zeroth to third laws. The above is illustrated using the Schlögl reaction with its multiple steady states in certain regions of operation. Full article

Venom plays a crucial role in the defense and predation of venomous animals. Spiders (Araneae) are among the most successful predators and have a fascinating venom composition. Their venom mainly contains disulfide-rich peptides and large proteins. Here, we analyzed spider venom protein families, utilizing transcriptomic and genomic data, and highlighted their similarities and differences. We show that spiders have specific combinations of toxins for better predation and defense, typically comprising a core toxin expressed alongside several auxiliary toxins. Among them, the CAP superfamily is widely distributed and highly expressed in web-building Araneoidea spiders. Our analysis of evolutionary relationships revealed four subfamilies (subA-subD) of the CAP superfamily that differ in structure and potential functions. CAP proteins are composed of a conserved CAP domain and diverse C-terminal domains. CAP subC shares similar domains with the snake ion channel regulator svCRISP proteins, while CAP subD possesses a sequence similar to that of insect venom allergen 5 (Ag5). Furthermore, we show that gene duplication and selective expression lead to increased expression of CAP subD, making it a core member of the CAP superfamily. This study sheds light on the functional diversity of CAP subfamilies and their evolutionary history, which has important implications for fully understanding the composition of spider venom proteins and the core toxin components of web-building spiders. Full article

The duration of ice-free periods in different parts of the Arctic Ocean plays a great role in processes in the climate system and defines the most comfortable sea ice conditions for economic activity. Based on satellite-derived sea ice concentration data acquired by passive microwave instruments, we identified the spatial distribution of the dates of sea ice retreat (DOR), dates of sea ice advance (DOA), and the resulting ice-free period duration (IFP) between these days for the Kara and Laptev seas during 1979–2022. The monthly decline in sea ice extent was detected from June to October in both seas, i.e., during the whole ice-free period. The annual mean sea ice extent during 2011–2021 decreased by 19.0% and 12.8% relative to the long-term average during 1981–2010 in the Kara and Laptev seas, respectively. The statistically significant (95% confidence level) positive IFP trends were detected for the majority of areas of the Kara and Laptev seas. Averaged IFP trends were estimated equal to +20.2 day/decade and +16.2 day/decade, respectively. The observed DOR tendency to earlier sea ice melting plays a greater role in the total IFP extension, as compared to later sea ice formation related to the DOA tendency. We reveal that regions of inflow of warm Atlantic waters to the Kara Sea demonstrate the largest long-term trends in DOA, DOR, and IFP associated with the decrease in ice coverage, that highlights the process of atlantification. Also, the Great Siberian Polynya in the Laptev Sea is the area of the largest long-term decreasing trend in DOR. Full article

Electronic devices play an increasingly vital role in modern society, and heat accumulation is a major concern during device development, which causes strong market demand for thermal conductivity materials and components. In this paper, a novel thermal conductive material consisting of polydimethylsiloxane (PDMS) and a binary filler system of h-BN platelets and Al₂O₃ nanoparticles was successfully fabricated using direct ink writing (DIW) 3D printing technology. The addictive manufacturing process not only endows the DIW-printed composites with various geometries but also promotes the construction of a 3D structural thermal conductive network through the shearing force during the printing process. Moreover, the integrity of the thermal conductive network can be optimized by filling the gaps between the BN platelets with Al₂O₃ particles. Resultingly, the configuration of the binary fillers is arranged by the shearing force during the DIW process, fabricating the thermal conductive network of oriented fillers. The DIW-printed BN/Al₂O₃/PDMS with 45 wt% thermal conductive binary filler can reach a thermal conductivity of 0.98 W/(m·K), higher than the 0.62 W/(m·K) of the control sample. In this study, a novel strategy for the thermal conductive performance improvement of composites based on DIW technology is successfully verified, paving a new way for thermal management. Full article

Technological advancements have expanded the range of methods for capturing human body motion, including solutions involving inertial sensors (IMUs) and optical alternatives. However, the rising complexity and costs associated with commercial solutions have prompted the exploration of more cost-effective alternatives. This paper presents a markerless optical motion capture system using a RealSense depth camera and intelligent computer vision algorithms. It facilitates precise posture assessment, the real-time calculation of joint angles, and acquisition of subject-specific anthropometric data for gait analysis. The proposed system stands out for its simplicity and affordability in comparison to complex commercial solutions. The gathered data are stored in comma-separated value (CSV) files, simplifying subsequent analysis and data mining. Preliminary tests, conducted in controlled laboratory environments and employing a commercial MEMS-IMU system as a reference, revealed a maximum relative error of 7.6% in anthropometric measurements, with a maximum absolute error of 4.67 cm at average height. Stride length measurements showed a maximum relative error of 11.2%. Static joint angle tests had a maximum average error of 10.2%, while dynamic joint angle tests showed a maximum average error of 9.06%. The proposed optical system offers sufficient accuracy for potential application in areas such as rehabilitation, sports analysis, and entertainment. Full article

Background/Objectives: There are limited data on the risks and benefits of using Andexanet alfa (AA) compared with four-factor prothrombin complex concentrate (4F-PCC) for the reversal of factor Xa inhibitor-associated intracranial hemorrhage (ICH). Our aim was to describe a compilation of the information available in the literature to date. Methods: PubMed, Embase, Web of Science (Clarivate Analytics) and the Cochrane Central Register of Controlled Trials were searched until December 2023. Following the “Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)” guidelines, our systematic literature review included studies that were retrospective in design and evaluated both drugs to control bleeding and complications (death and thromboembolic events). Two researchers re-examined the studies for relevance, extracted the data and assessed the risk of bias. No meta-analyses were performed for the results. Results: In this limited patient sample, we found no differences between published articles in terms of neuroimaging stability or thrombotic events. However, some studies show significant differences in mortality, suggesting that one of the AAs may be superior to 4F-PCC. Conclusions: Our qualitative analysis shows that AA has a better efficacy profile compared with 4F-PCC. However, further studies monitoring these patients and a multicenter collaborative network dedicated to this topic are needed. Full article

Under the auspice of further developing 5G mobile communication technology and integrating it with the latest advancements in the field of Industrial Internet-of-Things, this study conducts in-depth research and detailed analysis on the combination of 5G with industrial systems based on composite structures, communication network architectures, wireless application scenarios, and communication protocols. The status quo, development trend, and necessity of 5G mobile communication technology are explored and its potential in industrial applications is analyzed. Based on the current practical development level of 5G technology, by considering different requirements for bandwidth, real-time performance, and reliability in communication networks of industrial systems, this study proposes three feasible paths for the integration between 5G and industrial systems, including the method to use 5G in place of field buses. Finally, by introducing real-world cases, this study has successfully demonstrated the integration of 5G and industrial systems by extending 5G terminals as field bus gateways. This study provides valuable references for research and practice in related fields. Full article

Oral vaccines, unlike injected, induce intestinal secretory immunoglobulin A (sIgA) mimicking our natural defense against gut pathogens. We previously observed sIgA responses after administering the Clostridioides difficile colonisation factor CD0873 orally in enteric capsules to hamsters. Enteric-coated capsules are designed to resist dissolution in the stomach and disintegrate only at the higher pH of the small intestine. However, the variable responses between animals led us to speculate suboptimal transit of antigens to the small intestine. The rate of gastric emptying is a controlling factor in the passage of oral drugs for subsequent availability in the small intestine for absorption. Whilst in humans, food delays gastric emptying, in rats, capsules can empty quicker from fed stomachs than from fasted. To test in hamsters if fasting improves the delivery of antigens to the small intestine, as inferred from the immune responses generated, 24 animals were dosed intragastrically with enteric capsules containing recombinant CD0873. Twelve hamsters were fasted for 12 h prior to each dose and the other 12 fed. Significantly higher sIgA titres, with significantly greater bacterial-adherence-blocking activity, were detected in small intestinal lavages in the fasted group. We conclude that fasting in hamsters improves intestinal delivery leading to more robust responses. Full article

South Korea’s Particulate Matter (PM) concentration is among the highest among Organization for Economic Cooperation and Development (OECD) member countries. However, many studies in South Korea primarily focus on housing characteristics and the physical built environment when estimating apartment prices, often neglecting environmental factors. This study investigated factors influencing apartment prices using transaction data for Seoul apartments provided by the Ministry of Land, Infrastructure, and Transport (MOLIT) in 2019. For this purpose, the study compared and analyzed a traditional hedonic price model with a machine learning-based random forest model. The main findings are as follows: First, the evaluation results of the traditional hedonic price model and the machine learning-based random forest model indicated that the random forest model was found to be more suitable for predicting apartment prices. Second, an importance analysis using Explainable Artificial Intelligence (XAI) showed that PM is more important in determining apartment prices than access to education and bus stops, which were considered in this study. Finally, the study found that areas with higher concentrations of PM tend to have higher apartment prices. Therefore, when proposing policies to stabilize apartment prices, it is essential to consider environmental factors. Furthermore, it is necessary to devise measures such as assigning PM labels to apartments during the home purchasing process, enabling buyers to consider PM and obtain relevant information accordingly. Full article

Introduction: A Mediterranean diet has positive effects on the brain in mid-older adults; however, there is scarce information on pregnant individuals. We aimed to evaluate the effect of a structured Mediterranean diet intervention on the cortical structure of the maternal brain during pregnancy. Methods: This study was a secondary analysis of the IMPACT BCN, a randomized clinical trial with 1221 high-risk pregnant women randomly allocated into three groups at 19–23 weeks of gestation: Mediterranean diet intervention, a mindfulness-based stress reduction program, or usual care. Maternal brain magnetic resonance imaging was performed during the third trimester of pregnancy in a random subgroup of participants. For this study, data from the Mediterranean diet and usual groups were analyzed. Maternal dietary intake, adherence to the Mediterranean diet and metabolite biomarkers were evaluated using a food frequency questionnaire, a 17-item dietary screener and plasma/urine samples, respectively. Results: The cluster-wise analysis showed that the Mediterranean diet group participants (n = 34) had significantly larger surface areas in the right precuneus (90%CI: <0.0001–0.0004, p < 0.001) and left superior parietal (90%CI: 0.026–0.033, p = 0.03) lobules compared to the usual care group participants (n = 37). A larger right precuneus area was associated with high improvements in adherence to the Mediterranean diet, a high intake of walnuts and high concentrations of urinary hydroxytyrosol. A larger left superior parietal area was associated with a high intake of walnuts and high concentrations of urinary hydroxytyrosol. Conclusions: The promotion of a Mediterranean diet during pregnancy has a significant effect on maternal brain structure. Full article

The global navigation satellite system reflectometry (GNSS-R) technique has shown promise in retrieving sea levels using signal-to-noise ratio (SNR) data. However, its accuracy and performance are often limited compared to conventional tide gauges, particularly due to constraints in satellite elevation angles. To address these limitations, we propose a methodology integrating Long Short-Term Memory Deep Neural Networks (LSTM-DNN) models, utilising SNR residual sequences as key feature inputs. Our study focuses on the SC02 station, examining elevation angles ranging from 5° to 10°, 5° to 15°, and 5° to 20°. Results reveal notable reductions in root mean square errors (RMSE) of 2.855%, 17.519%, and 15.756%, respectively, showcasing improvements in accuracy across varying elevation angles. Of particular significance is the enhancement in precision observed at higher elevation angles. This underscores the valuable contribution of our approach to nearshore sea level wave height retrieval, promising advancements in the GNSS-R technique. Full article

In this research, the CuFeS₂/MXene-modified polyvinylidene fluoride (PVDF) membrane was prepared to activate peroxymonosulfate (PMS) to remove moxifloxacin (MOX) and its morphology; surface functional groups and hydrophilicity were also studied. The parameters of the catalytic membrane/PMS system were optimized, with an optimal loading of 4 mg/cm² and a PMS dosage of 0.20 mM. High filtration pressure, alkaline conditions, and impurities in water could inhibit MOX removal. After continuous filtration, the removal efficiency of MOX using the catalytic membrane/PMS system and PVDF membrane was 68.2% and 9.9%, respectively. Batch filtration could remove 87.8% MOX by the extra 10 min contact time between the catalytic membrane and solution. During the filtration process, CuFeS₂/MXene on the surface of the catalytic membrane activated PMS to produce SO₄^•−, HO^•, and ¹O₂, and MOX was removed through adsorption and degradation. Taking humic acid (HA) as the model foulant, reversible fouling resistance in the catalytic membrane/PMS system was 22.8% of the PVDF membrane. The catalytic membrane/PMS system weakened the formation of the cake layer by oxidizing HA into smaller pollutants and followed the intermediate blocking cake filtration model. The novelty of this research was to develop a CuFeS₂/MXene–PVDF membrane-activated PMS system and explore its application in antibiotics removal. Full article

Background and aims: This research aimed to evaluate the effects of consecutive intercropping on soil phosphorus (P) partitioning, concentrations, and sensitivity to P fertilizer application, elucidating its impact on soil P bioavailability. Methods: A field experiment investigated soil P fractions and content under continuous wheat and faba bean intercropping. Three P levels (0, 45, and 90 kg P₂O₅ ha⁻¹ denoted as P0, P1, and P2, respectively) and three planting patterns (monocropped wheat (MW), monocropped faba bean (MF), and wheat and faba bean intercropping (W//F)) were established since 2014. Aboveground P uptake by wheat and faba bean was determined. The soil P fractions and content were analyzed after six-, seven-, and eight-year continuous field experiments. Results: Wheat and faba bean intercropping increased wheat aboveground P uptake by 28.3–42.7% compared to MW under P1 and P2 levels and presented a P uptake advantage (LER_Puptake > 1), although W//F had no impact on faba bean P uptake. Consequently, continuous intercropping for 8 years decreased soil available P reserves by 9.0–23.4% in comparison to the weighted average value of MW and MF (It). Faba bean consumed greater non-labile and labile P than wheat with low P input. W//F had nearly no impact on the labile P pool but reduced the non-labile P pool by 5.0–12.1% under all P levels and lowered the moderately labile P pool by 1.7–4.7% at P0 and P1 levels compared to It with consecutive intercropping for 8 years. Consecutive intercropping of wheat and faba bean primarily decreased the proportion of Resin-P in the labile P pool and the proportion of Residual-P in the non-labile P pool. According to the structural equation model, crop P uptake mainly originated from soil available P, which was directly affected by non-labile P (Residual-P and Conc. HCl-P). In addition, intercropping changed the contribution of each P faction to crop P uptake compared to MW and MF, and P uptake in intercropping primarily depended on Conc. HCl- P and Dil. HCl-P. Therefore, consecutive intercropping decreased soil non-labile P and drove soil available P depletion, and intercropping’s increase of P uptake was related to the non-labile P mobilized to moderately labile and labile P. Conclusions: Continuous wheat and faba bean intercropping reduced non-labile P and led to soil available P depletion under low P input. This practice stimulated non-labile P mobilization, enhancing soil P fraction effectiveness and facilitating P uptake in intercropping. Continuous intercropping of wheat and faba bean is as an effective method to maximize the biological availability of soil P and reduce P application rates. Full article

This study aimed to investigate whether non-fasting plasma triglycerides were associated with diabetes mortality. It included 7312 US adult participants. Diabetes mortality data were obtained via the linkage to National Death Index (NDI) records. Hazard ratios of non-fasting plasma triglycerides for diabetes mortality were assessed using Cox proportional hazards models, adjusting for age, gender, ethnicity, obesity, poverty–income ratio, education levels, physical activity, alcohol consumption, cigarette smoking status, survey period, hypercholesterolemia, hypertension, diabetes, and family history of diabetes. Among these participants, 1180 had diabetes. A total of 420 diabetes-caused deaths were recorded during a mean follow-up of 16.8 years. A 1-natural-log-unit increase in non-fasting plasma triglycerides was associated with a 41% higher diabetes mortality risk (hazard ratio, 1.41; 95% confidence interval, 1.19–1.67). Participants with non-fasting plasma triglycerides in the highest quintile, versus those in the lowest quintile, had a 141% higher diabetes mortality risk (hazard ratio, 2.41; 95% confidence interval, 1.46–3.97). The positive association of non-fasting plasma triglycerides with diabetes mortality was independent of diabetes status at the baseline. In conclusion, this study demonstrated that non-fasting plasma triglycerides were positively associated with diabetes mortality, independent of diabetes status at baseline. Non-fasting triglycerides may be a therapeutic target for diabetes-related complications. Full article

Youth work is not unitary, has a diverse history, and draws upon differing traditions; however, the focus of all major youth work traditions has been anthropocentric. This approach is now challenged by young people themselves through the climate justice movement, and institutionally through the United Nations Agenda 2030 resolution, which has developed integrated Sustainable Development Goals, which aim to “balance” social, environmental, and economic imperatives. This article examines what insights can be gained from ecopedagogy that would enable youth work to fully integrate an ecological perspective alongside traditional anthropological concerns. The discussion focuses on the nexus and tensions between ecopedagogy and youth work from a theoretical perspective to draw out insights into how changes need to be made to the aims and purposes of youth work, how this might be achieved, and barriers in the current environment. Full article

The expression and function of podoplanin (PDPN) in the normal human placenta has been debated in placental evaluation. This study emphasizes the importance of a multimodal approach of PDPN expression in normal human placentas. A complete examination is performed using immunohistochemistry, RNAscope and automated Digital Image examination (DIA) interpretation. QuPath DIA-based analysis automatically generated the stromal and histological scores of PDPN expression for immunohistochemistry and RNAscope stains. The umbilical cord’s isolated fibroblasts and luminal structures expressed PDPN protein and PDPN_mRNA. RNAscope detected PDPN_mRNA upregulation in syncytial placental knots trophoblastic cells, but immunohistochemistry did not certify this at the protein level. The study found a significant correlation between the IHC and RNAscope H-Score (p = 0.033) and Allred Score (p = 0.05). A successful multimodal strategy for PDPN assessment in human placentas confirmed PDPN expression heterogeneity in the full-term human normal placenta and umbilical cord at the protein and mRNA level. In placental syncytial knots trophoblastic cells, PDPN showed mRNA overexpression, suggesting a potential role in placenta maturation. Full article

(1) Background: Breast cancer is the leading malignancy worldwide, and in Ghana, it has a poor overall survival rate. However, approximately 50% of cases are cases of early-stage disease, and with advances in breast cancer treatment and improvements in survival, quality of life (QOL) is becoming as important as the treatment of the disease. (2) Methodology: This was a cross-sectional study of survivors who had breast-conserving surgery (BCS), mastectomy only (M) and mastectomy with breast reconstruction (BRS) from 2016 to 2020 at a tertiary hospital in Ghana, comparatively assessing their QOL using EORTC QLQ C-30 and EORTC QLQ BR-23. (3) Results: The study participants had an overall global health status (GHS) median score of 83.3 [IQR: 66.7–91.7] with no significant differences between the surgery types. The BRS group had statistically significant lower median scores for the functional scale (82.8 and 51.0) and the highest scores for the symptomatic scale (15.7 and 16.5). Body image was significantly lowest for the BRS group (83.3) [68.8–91.7] and highest (100) [91.7–100] for the BCS group (p < 0.001). (4) Conclusion: There is a need to develop support systems tailored at improving the QOL of breast cancer survivors taking into consideration the type of surgery performed. Full article

Pearl millet [Pennisetum glaucum (L.) R. Br.] is a subtropical grain and forage crop. It is privileged with several desirable forage attributes. Nevertheless, research on pearl millet is limited, especially as a forage crop, in developing countries. Therefore, the objectives of this study were to investigate the field performance and stability of pearl millet genotypes for forage yield across seven environments. The study was conducted in seven environments (combination of locations and seasons) during the 2016/2017–2018/2019 seasons. Twenty-five pearl millet genotypes, selected based on forage yield from a core collection of 200 accessions, were arranged in an alpha lattice design with three replications. The parameters measured were fresh forage yield, days to flowering, plant height, number of culms m⁻², leaf-to-stem ratio, and stem girth. The combined analysis revealed that environments, genotypes, and their interaction had significant effects on all traits studied except the genotypic effect on stem girth. Across the seven environments, four genotypes (G14, G01, G12, and G22) outyielded the check genotype in fresh matter yield by 20.7, 16.5, 11.0 and 9.8%, respectively. The additive main effects and multiplicative interaction (AMMI) analysis showed that the genotype, environment, and their interaction were highly significant (p ≤ 0.001) for fresh matter yield. The results of AMMI stability values (ASVs) and the genotype selection index (GSI) combined with the AMMI estimate-based selection showed that genotypes G14, G22 and G01 were the most stable and adapted genotypes and were superior to the check genotype. These results indicate that forage pearl millet varieties could be developed directly through evaluating the wealth of available collections or indirectly through hybridization in crop breeding programs. Full article

Soccer is a sport with a high incidence of injuries. The most common injury occurs when the anterior cruciate ligament of the knee has undergone a sprain, strain, or partial or total rupture. Besides fitness factors (e.g., proprioception, balance and strength capabilities), a principal cause of ACL injuries is sport shoes and playing surfaces. Especially with the emergence of artificial surfaces (rubbers, turfs, concrete, asphalt, red turf), the ACL injuries dramatically increase. The cost of ACL injuries is high both in terms of career termination and in social and economic costs. Thus, it is necessary to understand the impact of sport shoes and playing surfaces on the ACL and how it can be mitigated. The present literature review followed the PRISMA methodology to identify the major biomechanical factors influencing the behavior of surfaces and shoes in relation to the ACL damage. Fifty-eight papers were identified. After reviewing the mechanism of injuries, we identified several distinct factors: type of outsole and mechanical arrangement of the outsoles; shear forces; characteristics of artificial turf surfaces; effect of weather on artificial surface aging and change in mechanical characteristics; outsole/ground interface; and the frictional, tractional and rotational forces in the pathogenesis of ACL injuries in soccer. Full article