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Reduced-Gravity Experiments Conducted to Help Bioreactor DevelopmentThe NASA Glenn Research Center and the NASA Johnson Space Center are collaborating on fluid dynamic investigations for a future cell science bioreactor to fly on the International Space Station (ISS). Project Manager Steven Gonda from the Cellular Biotechnology Program at Johnson is leading the development of the Hydrodynamic Focusing Bioreactor--Space (HFB-S) for use on the ISS to study tissue growth in microgravity. Glenn is providing microgravity fluid physics expertise to help with the design and evaluation of the HFB-S. These bioreactors are used for three-dimensional tissue culture, which cannot be done in ground-based labs in normal gravity. The bioreactors provide a continual supply of oxygen for cell growth, as well as periodic replacement of cell culture media with nutrients. The bioreactor must provide a uniform distribution of oxygen and nutrients while minimizing the shear stresses on the tissue culture.
Document ID
20050215403
Acquisition Source
Glenn Research Center
Document Type
Other
Authors
Niederhaus, Charles E. (NASA Glenn Research Center Cleveland, OH, United States)
Nahra, Henry K. (NASA Glenn Research Center Cleveland, OH, United States)
Kizito, John P. (National Center for Microgravity Research on Fluids and Combustion Cleveland, OH, United States)
Date Acquired
September 7, 2013
Publication Date
May 1, 2004
Publication Information
Publication: Research and Technology 2003
Subject Category
Life Sciences (General)
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

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